MotifTEAD4.H12INVIVO.1.P.B
Gene (human)TEAD4
(GeneCards)
Gene synonyms (human)RTEF1, TCF13L1, TEF3
Gene (mouse)Tead4
Gene synonyms (mouse)Tcf13r1, Tef3, Tefr1
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length16
ConsensusRMATTCCWRvvMbdbb
GC content47.01%
Information content (bits; total / per base)12.644 / 0.79
Data sourcesChIP-Seq
Aligned words1032

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 27 (163) 0.842 0.951 0.755 0.904 0.83 0.939 3.035 4.612 214.602 601.796
Mouse 17 (104) 0.89 0.957 0.8 0.919 0.861 0.94 3.24 4.539 202.933 447.319

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Non-Methyl HT-SELEX, 2 experiments median 0.83 0.796 0.715 0.697 0.623 0.626
best 0.894 0.867 0.765 0.749 0.654 0.66

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 9.759 16.299 0.125 0.037
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classTEA domain factors {3.6} (TFClass)
TF familyTEF1-related {3.6.1} (TFClass)
TF subfamily {3.6.1.0} (TFClass)
TFClass IDTFClass: 3.6.1.0.2
HGNCHGNC:11717
MGIMGI:106907
EntrezGene (human)GeneID:7004
(SSTAR profile)
EntrezGene (mouse)GeneID:21679
(SSTAR profile)
UniProt ID (human)TEAD4_HUMAN
UniProt ID (mouse)TEAD4_MOUSE
UniProt AC (human)Q15561
(TFClass)
UniProt AC (mouse)Q62296
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 27 human, 17 mouse
HT-SELEX 2
Methyl-HT-SELEX 0
PCM
ACGT
01539.013.0443.037.0
02243.0661.0128.00.0
031023.00.06.03.0
040.04.01.01027.0
0578.07.055.0892.0
063.0988.029.012.0
075.0878.01.0148.0
08375.065.039.0553.0
09152.0128.0628.0124.0
10246.0166.0511.0109.0
11267.0502.0234.029.0
12659.0163.095.0115.0
13117.0149.0146.0620.0
14248.0113.0264.0407.0
15115.0482.0232.0203.0
16101.0472.0159.0300.0
PFM
ACGT
010.5220.0130.4290.036
020.2350.6410.1240.0
030.9910.00.0060.003
040.00.0040.0010.995
050.0760.0070.0530.864
060.0030.9570.0280.012
070.0050.8510.0010.143
080.3630.0630.0380.536
090.1470.1240.6090.12
100.2380.1610.4950.106
110.2590.4860.2270.028
120.6390.1580.0920.111
130.1130.1440.1410.601
140.240.1090.2560.394
150.1110.4670.2250.197
160.0980.4570.1540.291
PWM
ACGT
010.733-2.8690.538-1.903
02-0.0590.937-0.694-5.009
031.373-5.009-3.514-4.005
04-5.009-3.813-4.5541.376
05-1.181-3.392-1.5211.236
06-4.0051.338-2.134-2.94
07-3.6521.22-4.554-0.551
080.372-1.359-1.8530.759
09-0.524-0.6940.886-0.725
10-0.047-0.4370.68-0.853
110.0340.662-0.097-2.134
120.934-0.455-0.988-0.8
13-0.783-0.544-0.5640.873
14-0.039-0.8170.0230.453
15-0.80.622-0.105-0.238
16-0.9280.601-0.480.15
Standard thresholds
P-value Threshold
0.001 3.91861
0.0005 5.01036
0.0001 7.18966