TEAD3.H12INVIVO.1.S.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	TEAD3.H12INVIVO.1.S.B
Gene (human)	TEAD3 (GeneCards)
Gene synonyms (human)	TEAD5, TEF5
Gene (mouse)	Tead3
Gene synonyms (mouse)	Tcf13r2, Tef5
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	18
Consensus	nRCATTCCdndMRWWYYn
GC content	44.94%
Information content (bits; total / per base)	15.221 / 0.846
Data sources	HT-SELEX
Aligned words	2493

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (7)	0.819	0.826	0.714	0.729	0.82	0.829	3.035	3.198	226.229	266.886

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 2 experiments	median	0.998	0.998	0.973	0.971	0.891	0.896
Non-Methyl HT-SELEX, 2 experiments	best	1.0	1.0	1.0	0.999	0.978	0.978

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	TEA domain factors {3.6} (TFClass)
TF family	TEF1-related {3.6.1} (TFClass)
TF subfamily	{3.6.1.0} (TFClass)
TFClass ID	TFClass: 3.6.1.0.4
HGNC	HGNC:11716
MGI	MGI:109241
EntrezGene (human)	GeneID:7005 (SSTAR profile)
EntrezGene (mouse)	GeneID:21678 (SSTAR profile)
UniProt ID (human)	TEAD3_HUMAN
UniProt ID (mouse)	TEAD3_MOUSE
UniProt AC (human)	Q99594 (TFClass)
UniProt AC (mouse)	P70210 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 0 mouse
HT-SELEX	2
Methyl-HT-SELEX	0

PCM	TEAD3.H12INVIVO.1.S.B.pcm
PWM	TEAD3.H12INVIVO.1.S.B.pwm
PFM	TEAD3.H12INVIVO.1.S.B.pfm
Alignment	TEAD3.H12INVIVO.1.S.B.words.tsv
Threshold to P-value map	TEAD3.H12INVIVO.1.S.B.thr
Motif in other formats
JASPAR format	TEAD3.H12INVIVO.1.S.B_jaspar_format.txt
MEME format	TEAD3.H12INVIVO.1.S.B_meme_format.meme
Transfac format	TEAD3.H12INVIVO.1.S.B_transfac_format.txt
Homer format	TEAD3.H12INVIVO.1.S.B_homer_format_0.001.txt TEAD3.H12INVIVO.1.S.B_homer_format_0.0005.txt TEAD3.H12INVIVO.1.S.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	468.0	815.0	438.0	772.0
02	1220.0	85.0	1101.0	87.0
03	274.0	2178.0	35.0	6.0
04	2467.0	5.0	19.0	2.0
05	6.0	3.0	3.0	2481.0
06	160.0	5.0	20.0	2308.0
07	4.0	2439.0	25.0	25.0
08	14.0	2204.0	25.0	250.0
09	1006.0	144.0	359.0	984.0
10	633.0	626.0	553.0	681.0
11	928.0	258.0	999.0	308.0
12	528.0	1607.0	244.0	114.0
13	1879.0	212.0	220.0	182.0
14	258.0	233.0	153.0	1849.0
15	429.0	238.0	260.0	1566.0
16	243.0	1791.0	178.0	281.0
17	254.25	1634.25	158.25	446.25
18	847.25	449.25	450.25	746.25

PFM

	A	C	G	T
01	0.188	0.327	0.176	0.31
02	0.489	0.034	0.442	0.035
03	0.11	0.874	0.014	0.002
04	0.99	0.002	0.008	0.001
05	0.002	0.001	0.001	0.995
06	0.064	0.002	0.008	0.926
07	0.002	0.978	0.01	0.01
08	0.006	0.884	0.01	0.1
09	0.404	0.058	0.144	0.395
10	0.254	0.251	0.222	0.273
11	0.372	0.103	0.401	0.124
12	0.212	0.645	0.098	0.046
13	0.754	0.085	0.088	0.073
14	0.103	0.093	0.061	0.742
15	0.172	0.095	0.104	0.628
16	0.097	0.718	0.071	0.113
17	0.102	0.656	0.063	0.179
18	0.34	0.18	0.181	0.299

PWM

	A	C	G	T
01	-0.285	0.268	-0.351	0.213
02	0.67	-1.973	0.568	-1.95
03	-0.818	1.249	-2.828	-4.364
04	1.373	-4.499	-3.396	-5.063
05	-4.364	-4.838	-4.838	1.379
06	-1.351	-4.499	-3.349	1.307
07	-4.654	1.362	-3.144	-3.144
08	-3.668	1.261	-3.144	-0.909
09	0.478	-1.455	-0.549	0.456
10	0.015	0.004	-0.119	0.088
11	0.397	-0.878	0.471	-0.702
12	-0.165	0.945	-0.933	-1.685
13	1.101	-1.072	-1.036	-1.223
14	-0.878	-0.979	-1.395	1.085
15	-0.372	-0.958	-0.87	0.919
16	-0.937	1.054	-1.245	-0.793
17	-0.892	0.962	-1.362	-0.333
18	0.306	-0.326	-0.324	0.18

Standard thresholds

P-value	Threshold
0.001	2.73571
0.0005	3.97046
0.0001	6.52166