TEAD3.H12INVITRO.1.S.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	TEAD3.H12INVITRO.1.S.B
Gene (human)	TEAD3 (GeneCards)
Gene synonyms (human)	TEAD5, TEF5
Gene (mouse)	Tead3
Gene synonyms (mouse)	Tcf13r2, Tef5
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	18
Consensus	nRCATTCCdnRCATWCCd
GC content	44.19%
Information content (bits; total / per base)	19.592 / 1.088
Data sources	HT-SELEX
Aligned words	7183

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (7)	0.723	0.735	0.624	0.643	0.731	0.746	2.745	2.941	135.292	165.018

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 2 experiments	median	0.999	0.999	0.974	0.972	0.888	0.895
Non-Methyl HT-SELEX, 2 experiments	best	1.0	1.0	1.0	1.0	0.977	0.977

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	TEA domain factors {3.6} (TFClass)
TF family	TEF1-related {3.6.1} (TFClass)
TF subfamily	{3.6.1.0} (TFClass)
TFClass ID	TFClass: 3.6.1.0.4
HGNC	HGNC:11716
MGI	MGI:109241
EntrezGene (human)	GeneID:7005 (SSTAR profile)
EntrezGene (mouse)	GeneID:21678 (SSTAR profile)
UniProt ID (human)	TEAD3_HUMAN
UniProt ID (mouse)	TEAD3_MOUSE
UniProt AC (human)	Q99594 (TFClass)
UniProt AC (mouse)	P70210 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 0 mouse
HT-SELEX	2
Methyl-HT-SELEX	0

PCM	TEAD3.H12INVITRO.1.S.B.pcm
PWM	TEAD3.H12INVITRO.1.S.B.pwm
PFM	TEAD3.H12INVITRO.1.S.B.pfm
Alignment	TEAD3.H12INVITRO.1.S.B.words.tsv
Threshold to P-value map	TEAD3.H12INVITRO.1.S.B.thr
Motif in other formats
JASPAR format	TEAD3.H12INVITRO.1.S.B_jaspar_format.txt
MEME format	TEAD3.H12INVITRO.1.S.B_meme_format.meme
Transfac format	TEAD3.H12INVITRO.1.S.B_transfac_format.txt
Homer format	TEAD3.H12INVITRO.1.S.B_homer_format_0.001.txt TEAD3.H12INVITRO.1.S.B_homer_format_0.0005.txt TEAD3.H12INVITRO.1.S.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1460.0	2467.0	1202.0	2054.0
02	3599.5	164.5	3205.5	213.5
03	849.0	6221.0	97.0	16.0
04	7132.0	11.0	39.0	1.0
05	2.0	4.0	4.0	7173.0
06	608.0	7.0	93.0	6475.0
07	33.0	7059.0	53.0	38.0
08	50.0	6163.0	48.0	922.0
09	2591.0	418.0	938.0	3236.0
10	1901.0	2000.0	1609.0	1673.0
11	3126.0	214.0	3454.0	389.0
12	1347.0	5557.0	228.0	51.0
13	6827.0	90.0	223.0	43.0
14	108.0	132.0	55.0	6888.0
15	1272.0	94.0	381.0	5436.0
16	196.0	6545.0	185.0	257.0
17	257.25	5850.25	169.25	906.25
18	2708.5	831.5	1319.5	2323.5

PFM

	A	C	G	T
01	0.203	0.343	0.167	0.286
02	0.501	0.023	0.446	0.03
03	0.118	0.866	0.014	0.002
04	0.993	0.002	0.005	0.0
05	0.0	0.001	0.001	0.999
06	0.085	0.001	0.013	0.901
07	0.005	0.983	0.007	0.005
08	0.007	0.858	0.007	0.128
09	0.361	0.058	0.131	0.451
10	0.265	0.278	0.224	0.233
11	0.435	0.03	0.481	0.054
12	0.188	0.774	0.032	0.007
13	0.95	0.013	0.031	0.006
14	0.015	0.018	0.008	0.959
15	0.177	0.013	0.053	0.757
16	0.027	0.911	0.026	0.036
17	0.036	0.814	0.024	0.126
18	0.377	0.116	0.184	0.323

PWM

	A	C	G	T
01	-0.207	0.317	-0.401	0.134
02	0.695	-2.378	0.579	-2.12
03	-0.748	1.242	-2.897	-4.592
04	1.378	-4.913	-3.775	-6.325
05	-6.055	-5.667	-5.667	1.384
06	-1.081	-5.273	-2.938	1.282
07	-3.933	1.368	-3.483	-3.8
08	-3.539	1.232	-3.578	-0.665
09	0.366	-1.454	-0.648	0.588
10	0.057	0.108	-0.11	-0.071
11	0.554	-2.118	0.654	-1.525
12	-0.287	1.129	-2.055	-3.52
13	1.335	-2.97	-2.077	-3.683
14	-2.792	-2.595	-3.448	1.343
15	-0.344	-2.928	-1.546	1.107
16	-2.205	1.292	-2.262	-1.937
17	-1.936	1.18	-2.35	-0.683
18	0.411	-0.769	-0.308	0.257

Standard thresholds

P-value	Threshold
0.001	-0.26569
0.0005	1.27781
0.0001	4.51586