TEAD3.H12CORE.1.S.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	TEAD3.H12CORE.1.S.B
Gene (human)	TEAD3 (GeneCards)
Gene synonyms (human)	TEAD5, TEF5
Gene (mouse)	Tead3
Gene synonyms (mouse)	Tcf13r2, Tef5
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	18
Consensus	nRCATTCCdndMRWWYYn
GC content	44.72%
Information content (bits; total / per base)	15.7 / 0.872
Data sources	HT-SELEX
Aligned words	9831

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (7)	0.806	0.813	0.699	0.713	0.811	0.819	3.02	3.18	212.796	243.347

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 2 experiments	median	0.999	0.998	0.974	0.972	0.893	0.898
Non-Methyl HT-SELEX, 2 experiments	best	1.0	1.0	1.0	1.0	0.979	0.979

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	TEA domain factors {3.6} (TFClass)
TF family	TEF1-related {3.6.1} (TFClass)
TF subfamily	{3.6.1.0} (TFClass)
TFClass ID	TFClass: 3.6.1.0.4
HGNC	HGNC:11716
MGI	MGI:109241
EntrezGene (human)	GeneID:7005 (SSTAR profile)
EntrezGene (mouse)	GeneID:21678 (SSTAR profile)
UniProt ID (human)	TEAD3_HUMAN
UniProt ID (mouse)	TEAD3_MOUSE
UniProt AC (human)	Q99594 (TFClass)
UniProt AC (mouse)	P70210 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 0 mouse
HT-SELEX	2
Methyl-HT-SELEX	0

PCM	TEAD3.H12CORE.1.S.B.pcm
PWM	TEAD3.H12CORE.1.S.B.pwm
PFM	TEAD3.H12CORE.1.S.B.pfm
Alignment	TEAD3.H12CORE.1.S.B.words.tsv
Threshold to P-value map	TEAD3.H12CORE.1.S.B.thr
Motif in other formats
JASPAR format	TEAD3.H12CORE.1.S.B_jaspar_format.txt
MEME format	TEAD3.H12CORE.1.S.B_meme_format.meme
Transfac format	TEAD3.H12CORE.1.S.B_transfac_format.txt
Homer format	TEAD3.H12CORE.1.S.B_homer_format_0.001.txt TEAD3.H12CORE.1.S.B_homer_format_0.0005.txt TEAD3.H12CORE.1.S.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1948.5	3354.5	1674.5	2853.5
02	4869.5	206.5	4478.5	276.5
03	1174.0	8508.0	121.0	28.0
04	9746.0	19.0	63.0	3.0
05	6.0	9.0	5.0	9811.0
06	777.0	12.0	148.0	8894.0
07	46.0	9639.0	80.0	66.0
08	72.0	8504.0	83.0	1172.0
09	3605.0	560.0	1398.0	4268.0
10	2561.0	2713.0	2181.0	2376.0
11	3950.0	767.0	4211.0	903.0
12	2081.0	6431.0	912.0	407.0
13	7688.0	722.0	818.0	603.0
14	858.0	833.0	504.0	7636.0
15	2044.0	811.0	921.0	6055.0
16	920.0	7335.0	558.0	1018.0
17	827.25	6581.25	569.25	1853.25
18	3318.25	1650.25	1754.25	3108.25

PFM

	A	C	G	T
01	0.198	0.341	0.17	0.29
02	0.495	0.021	0.456	0.028
03	0.119	0.865	0.012	0.003
04	0.991	0.002	0.006	0.0
05	0.001	0.001	0.001	0.998
06	0.079	0.001	0.015	0.905
07	0.005	0.98	0.008	0.007
08	0.007	0.865	0.008	0.119
09	0.367	0.057	0.142	0.434
10	0.261	0.276	0.222	0.242
11	0.402	0.078	0.428	0.092
12	0.212	0.654	0.093	0.041
13	0.782	0.073	0.083	0.061
14	0.087	0.085	0.051	0.777
15	0.208	0.082	0.094	0.616
16	0.094	0.746	0.057	0.104
17	0.084	0.669	0.058	0.189
18	0.338	0.168	0.178	0.316

PWM

	A	C	G	T
01	-0.232	0.311	-0.383	0.149
02	0.683	-2.467	0.6	-2.177
03	-0.738	1.241	-2.993	-4.397
04	1.377	-4.749	-3.629	-6.141
05	-5.692	-5.383	-5.82	1.384
06	-1.15	-5.148	-2.795	1.285
07	-3.931	1.366	-3.398	-3.584
08	-3.5	1.241	-3.362	-0.74
09	0.383	-1.476	-0.563	0.552
10	0.041	0.099	-0.119	-0.034
11	0.474	-1.162	0.538	-1.0
12	-0.166	0.961	-0.99	-1.793
13	1.14	-1.223	-1.098	-1.402
14	-1.051	-1.08	-1.581	1.133
15	-0.184	-1.107	-0.98	0.901
16	-0.981	1.093	-1.479	-0.88
17	-1.087	0.984	-1.46	-0.282
18	0.3	-0.398	-0.337	0.235

Standard thresholds

P-value	Threshold
0.001	2.38371
0.0005	3.68176
0.0001	6.34506