TEAD3.H12CORE.0.PS.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	TEAD3.H12CORE.0.PS.A
Gene (human)	TEAD3 (GeneCards)
Gene synonyms (human)	TEAD5, TEF5
Gene (mouse)	Tead3
Gene synonyms (mouse)	Tcf13r2, Tef5
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	13
Consensus	bhRCATTCCWSvv
GC content	51.83%
Information content (bits; total / per base)	12.028 / 0.925
Data sources	ChIP-Seq + HT-SELEX
Aligned words	1000

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (7)	0.907	0.917	0.842	0.863	0.901	0.911	3.87	4.099	374.824	474.796

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 2 experiments	median	0.982	0.969	0.957	0.942	0.88	0.873
Non-Methyl HT-SELEX, 2 experiments	best	0.993	0.988	0.99	0.983	0.965	0.956

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	TEA domain factors {3.6} (TFClass)
TF family	TEF1-related {3.6.1} (TFClass)
TF subfamily	{3.6.1.0} (TFClass)
TFClass ID	TFClass: 3.6.1.0.4
HGNC	HGNC:11716
MGI	MGI:109241
EntrezGene (human)	GeneID:7005 (SSTAR profile)
EntrezGene (mouse)	GeneID:21678 (SSTAR profile)
UniProt ID (human)	TEAD3_HUMAN
UniProt ID (mouse)	TEAD3_MOUSE
UniProt AC (human)	Q99594 (TFClass)
UniProt AC (mouse)	P70210 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 0 mouse
HT-SELEX	2
Methyl-HT-SELEX	0

PCM	TEAD3.H12CORE.0.PS.A.pcm
PWM	TEAD3.H12CORE.0.PS.A.pwm
PFM	TEAD3.H12CORE.0.PS.A.pfm
Alignment	TEAD3.H12CORE.0.PS.A.words.tsv
Threshold to P-value map	TEAD3.H12CORE.0.PS.A.thr
Motif in other formats
JASPAR format	TEAD3.H12CORE.0.PS.A_jaspar_format.txt
MEME format	TEAD3.H12CORE.0.PS.A_meme_format.meme
Transfac format	TEAD3.H12CORE.0.PS.A_transfac_format.txt
Homer format	TEAD3.H12CORE.0.PS.A_homer_format_0.001.txt TEAD3.H12CORE.0.PS.A_homer_format_0.0005.txt TEAD3.H12CORE.0.PS.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	151.0	402.0	177.0	270.0
02	147.0	405.0	131.0	317.0
03	499.0	19.0	424.0	58.0
04	103.0	862.0	35.0	0.0
05	956.0	14.0	22.0	8.0
06	4.0	1.0	9.0	986.0
07	58.0	7.0	33.0	902.0
08	1.0	975.0	9.0	15.0
09	2.0	933.0	0.0	65.0
10	486.0	45.0	40.0	429.0
11	112.0	136.0	634.0	118.0
12	187.0	364.0	331.0	118.0
13	187.0	483.0	247.0	83.0

PFM

	A	C	G	T
01	0.151	0.402	0.177	0.27
02	0.147	0.405	0.131	0.317
03	0.499	0.019	0.424	0.058
04	0.103	0.862	0.035	0.0
05	0.956	0.014	0.022	0.008
06	0.004	0.001	0.009	0.986
07	0.058	0.007	0.033	0.902
08	0.001	0.975	0.009	0.015
09	0.002	0.933	0.0	0.065
10	0.486	0.045	0.04	0.429
11	0.112	0.136	0.634	0.118
12	0.187	0.364	0.331	0.118
13	0.187	0.483	0.247	0.083

PWM

	A	C	G	T
01	-0.5	0.472	-0.342	0.076
02	-0.526	0.48	-0.64	0.236
03	0.688	-2.497	0.525	-1.439
04	-0.877	1.233	-1.925	-4.982
05	1.336	-2.773	-2.362	-3.253
06	-3.783	-4.525	-3.156	1.367
07	-1.439	-3.362	-1.981	1.278
08	-4.525	1.356	-3.156	-2.711
09	-4.213	1.312	-4.982	-1.328
10	0.661	-1.684	-1.797	0.537
11	-0.795	-0.603	0.926	-0.743
12	-0.288	0.374	0.279	-0.743
13	-0.288	0.655	-0.012	-1.089

Standard thresholds

P-value	Threshold
0.001	4.08666
0.0005	5.138065
0.0001	7.258815