MotifTEAD2.H12CORE.0.PSM.A
Gene (human)TEAD2
(GeneCards)
Gene synonyms (human)TEF4
Gene (mouse)Tead2
Gene synonyms (mouse)Etdf, Etf, Tef4
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
A
Motif length13
ConsensusnbRCATTCCWndn
GC content47.61%
Information content (bits; total / per base)13.535 / 1.041
Data sourcesChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words9657

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 1 (6) 0.792 0.81 0.656 0.698 0.776 0.786 2.367 2.406 115.59 135.222
Mouse 1 (7) 0.871 0.893 0.773 0.797 0.85 0.864 2.797 2.829 121.509 243.886

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 2 experiments median 0.998 0.997 0.996 0.994 0.988 0.983
best 0.998 0.998 0.997 0.995 0.99 0.987
Methyl HT-SELEX, 1 experiments median 0.998 0.997 0.995 0.993 0.985 0.98
best 0.998 0.997 0.995 0.993 0.985 0.98
Non-Methyl HT-SELEX, 1 experiments median 0.998 0.998 0.997 0.995 0.99 0.987
best 0.998 0.998 0.997 0.995 0.99 0.987

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.829 0.615 0.818 0.634
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classTEA domain factors {3.6} (TFClass)
TF familyTEF1-related {3.6.1} (TFClass)
TF subfamily {3.6.1.0} (TFClass)
TFClass IDTFClass: 3.6.1.0.3
HGNCHGNC:11715
MGIMGI:104904
EntrezGene (human)GeneID:8463
(SSTAR profile)
EntrezGene (mouse)GeneID:21677
(SSTAR profile)
UniProt ID (human)TEAD2_HUMAN
UniProt ID (mouse)TEAD2_MOUSE
UniProt AC (human)Q15562
(TFClass)
UniProt AC (mouse)P48301
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 1 human, 1 mouse
HT-SELEX 1
Methyl-HT-SELEX 1
PCM
ACGT
012203.03566.01814.02074.0
021094.05428.01277.01858.0
034367.060.05186.044.0
04543.09106.06.02.0
059655.00.01.01.0
060.00.00.09657.0
07185.00.00.09472.0
080.09657.00.00.0
091.09529.02.0125.0
105884.0154.01255.02364.0
112787.02238.01421.03211.0
122878.01497.01610.03672.0
132056.253171.252796.251633.25
PFM
ACGT
010.2280.3690.1880.215
020.1130.5620.1320.192
030.4520.0060.5370.005
040.0560.9430.0010.0
051.00.00.00.0
060.00.00.01.0
070.0190.00.00.981
080.01.00.00.0
090.00.9870.00.013
100.6090.0160.130.245
110.2890.2320.1470.333
120.2980.1550.1670.38
130.2130.3280.290.169
PWM
ACGT
01-0.0910.39-0.286-0.152
02-0.790.81-0.636-0.262
030.592-3.6580.764-3.955
04-1.4891.327-5.675-6.333
051.385-6.96-6.598-6.598
06-6.96-6.96-6.961.386
07-2.557-6.96-6.961.366
08-6.961.386-6.96-6.96
09-6.5981.372-6.333-2.944
100.89-2.738-0.653-0.021
110.143-0.076-0.5290.285
120.176-0.477-0.4050.419
13-0.160.2730.147-0.39
Standard thresholds
P-value Threshold
0.001 1.48046
0.0005 3.15917
0.0001 7.077475