| Motif | TEAD1.H12INVITRO.2.S.C |
| Gene (human) | TEAD1 (GeneCards) |
| Gene synonyms (human) | TCF13, TEF1 |
| Gene (mouse) | Tead1 |
| Gene synonyms (mouse) | Tcf13, Tef-1, Tef1 |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 2 |
| Quality | C |
| Motif | TEAD1.H12INVITRO.2.S.C |
| Gene (human) | TEAD1 (GeneCards) |
| Gene synonyms (human) | TCF13, TEF1 |
| Gene (mouse) | Tead1 |
| Gene synonyms (mouse) | Tcf13, Tef-1, Tef1 |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 2 |
| Quality | C |
| Motif length | 19 |
| Consensus | nRCATTCCdnRCATTCChn |
| GC content | 42.78% |
| Information content (bits; total / per base) | 21.339 / 1.123 |
| Data sources | HT-SELEX |
| Aligned words | 299 |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | 12 (82) | 0.698 | 0.828 | 0.62 | 0.741 | 0.729 | 0.87 | 2.781 | 3.846 | 129.114 | 340.301 |
| Mouse | 5 (31) | 0.651 | 0.801 | 0.534 | 0.737 | 0.651 | 0.822 | 2.047 | 3.54 | 128.721 | 236.854 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 4 experiments | median | 0.84 | 0.823 | 0.772 | 0.755 | 0.713 | 0.7 |
| best | 0.965 | 0.944 | 0.93 | 0.902 | 0.869 | 0.839 | |
| Methyl HT-SELEX, 1 experiments | median | 0.965 | 0.944 | 0.93 | 0.902 | 0.869 | 0.839 |
| best | 0.965 | 0.944 | 0.93 | 0.902 | 0.869 | 0.839 | |
| Non-Methyl HT-SELEX, 3 experiments | median | 0.725 | 0.713 | 0.625 | 0.623 | 0.568 | 0.575 |
| best | 0.956 | 0.932 | 0.919 | 0.886 | 0.858 | 0.824 | |
| rSNP benchmarking, ADASTRA | odds-ratio | -log-Fisher's P | Pearson r | Kendall tau |
|---|---|---|---|---|
| # | 6.509 | 1.978 | 0.238 | 0.086 |
| rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
|---|---|---|---|---|
| batch 2 | 0.72 | 0.39 | 0.704 | 0.512 |
| TF superclass | Helix-turn-helix domains {3} (TFClass) |
| TF class | TEA domain factors {3.6} (TFClass) |
| TF family | TEF1-related {3.6.1} (TFClass) |
| TF subfamily | {3.6.1.0} (TFClass) |
| TFClass ID | TFClass: 3.6.1.0.1 |
| HGNC | HGNC:11714 |
| MGI | MGI:101876 |
| EntrezGene (human) | GeneID:7003 (SSTAR profile) |
| EntrezGene (mouse) | |
| UniProt ID (human) | TEAD1_HUMAN |
| UniProt ID (mouse) | TEAD1_MOUSE |
| UniProt AC (human) | P28347 (TFClass) |
| UniProt AC (mouse) | P30051 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 12 human, 5 mouse |
| HT-SELEX | 3 |
| Methyl-HT-SELEX | 1 |
| PCM | TEAD1.H12INVITRO.2.S.C.pcm |
| PWM | TEAD1.H12INVITRO.2.S.C.pwm |
| PFM | TEAD1.H12INVITRO.2.S.C.pfm |
| Alignment | TEAD1.H12INVITRO.2.S.C.words.tsv |
| Threshold to P-value map | TEAD1.H12INVITRO.2.S.C.thr |
| Motif in other formats | |
| JASPAR format | TEAD1.H12INVITRO.2.S.C_jaspar_format.txt |
| MEME format | TEAD1.H12INVITRO.2.S.C_meme_format.meme |
| Transfac format | TEAD1.H12INVITRO.2.S.C_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 51.0 | 69.0 | 75.0 | 104.0 |
| 02 | 151.5 | 7.5 | 131.5 | 8.5 |
| 03 | 59.0 | 231.0 | 3.0 | 6.0 |
| 04 | 292.0 | 1.0 | 0.0 | 6.0 |
| 05 | 1.0 | 5.0 | 0.0 | 293.0 |
| 06 | 8.0 | 3.0 | 6.0 | 282.0 |
| 07 | 0.0 | 286.0 | 3.0 | 10.0 |
| 08 | 4.0 | 254.0 | 2.0 | 39.0 |
| 09 | 101.0 | 23.0 | 32.0 | 143.0 |
| 10 | 64.0 | 71.0 | 73.0 | 91.0 |
| 11 | 148.0 | 8.0 | 136.0 | 7.0 |
| 12 | 67.0 | 229.0 | 3.0 | 0.0 |
| 13 | 297.0 | 0.0 | 2.0 | 0.0 |
| 14 | 0.0 | 0.0 | 0.0 | 299.0 |
| 15 | 13.0 | 0.0 | 6.0 | 280.0 |
| 16 | 1.0 | 294.0 | 0.0 | 4.0 |
| 17 | 4.0 | 263.0 | 0.0 | 32.0 |
| 18 | 133.25 | 51.25 | 39.25 | 75.25 |
| 19 | 100.5 | 81.5 | 41.5 | 75.5 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.171 | 0.231 | 0.251 | 0.348 |
| 02 | 0.507 | 0.025 | 0.44 | 0.028 |
| 03 | 0.197 | 0.773 | 0.01 | 0.02 |
| 04 | 0.977 | 0.003 | 0.0 | 0.02 |
| 05 | 0.003 | 0.017 | 0.0 | 0.98 |
| 06 | 0.027 | 0.01 | 0.02 | 0.943 |
| 07 | 0.0 | 0.957 | 0.01 | 0.033 |
| 08 | 0.013 | 0.849 | 0.007 | 0.13 |
| 09 | 0.338 | 0.077 | 0.107 | 0.478 |
| 10 | 0.214 | 0.237 | 0.244 | 0.304 |
| 11 | 0.495 | 0.027 | 0.455 | 0.023 |
| 12 | 0.224 | 0.766 | 0.01 | 0.0 |
| 13 | 0.993 | 0.0 | 0.007 | 0.0 |
| 14 | 0.0 | 0.0 | 0.0 | 1.0 |
| 15 | 0.043 | 0.0 | 0.02 | 0.936 |
| 16 | 0.003 | 0.983 | 0.0 | 0.013 |
| 17 | 0.013 | 0.88 | 0.0 | 0.107 |
| 18 | 0.446 | 0.171 | 0.131 | 0.252 |
| 19 | 0.336 | 0.273 | 0.139 | 0.253 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.374 | -0.078 | 0.003 | 0.325 |
| 02 | 0.697 | -2.144 | 0.557 | -2.038 |
| 03 | -0.232 | 1.116 | -2.846 | -2.328 |
| 04 | 1.349 | -3.447 | -3.979 | -2.328 |
| 05 | -3.447 | -2.473 | -3.979 | 1.352 |
| 06 | -2.09 | -2.846 | -2.328 | 1.314 |
| 07 | -3.979 | 1.328 | -2.846 | -1.897 |
| 08 | -2.642 | 1.21 | -3.102 | -0.634 |
| 09 | 0.296 | -1.137 | -0.824 | 0.64 |
| 10 | -0.152 | -0.05 | -0.023 | 0.193 |
| 11 | 0.674 | -2.09 | 0.59 | -2.202 |
| 12 | -0.107 | 1.107 | -2.846 | -3.979 |
| 13 | 1.365 | -3.979 | -3.102 | -3.979 |
| 14 | -3.979 | -3.979 | -3.979 | 1.372 |
| 15 | -1.664 | -3.979 | -2.328 | 1.307 |
| 16 | -3.447 | 1.355 | -3.979 | -2.642 |
| 17 | -2.642 | 1.245 | -3.979 | -0.824 |
| 18 | 0.57 | -0.369 | -0.627 | 0.007 |
| 19 | 0.291 | 0.085 | -0.574 | 0.01 |
| P-value | Threshold |
|---|---|
| 0.001 | -0.38259 |
| 0.0005 | 1.11111 |
| 0.0001 | 4.27956 |