MotifTEAD1.H12CORE.2.S.C
Gene (human)TEAD1
(GeneCards)
Gene synonyms (human)TCF13, TEF1
Gene (mouse)Tead1
Gene synonyms (mouse)Tcf13, Tef-1, Tef1
LOGO
LOGO (reverse complement)
Motif subtype2
Quality
C
Motif length19
ConsensusnRCATTCCdnRCATTCChn
GC content42.78%
Information content (bits; total / per base)21.339 / 1.123
Data sourcesHT-SELEX
Aligned words299

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 12 (82) 0.698 0.828 0.62 0.741 0.729 0.87 2.781 3.846 129.114 340.301
Mouse 5 (31) 0.651 0.801 0.534 0.737 0.651 0.822 2.047 3.54 128.721 236.854

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.84 0.823 0.772 0.755 0.713 0.7
best 0.965 0.944 0.93 0.902 0.869 0.839
Methyl HT-SELEX, 1 experiments median 0.965 0.944 0.93 0.902 0.869 0.839
best 0.965 0.944 0.93 0.902 0.869 0.839
Non-Methyl HT-SELEX, 3 experiments median 0.725 0.713 0.625 0.623 0.568 0.575
best 0.956 0.932 0.919 0.886 0.858 0.824

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 6.509 1.978 0.238 0.086

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.72 0.39 0.704 0.512
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classTEA domain factors {3.6} (TFClass)
TF familyTEF1-related {3.6.1} (TFClass)
TF subfamily {3.6.1.0} (TFClass)
TFClass IDTFClass: 3.6.1.0.1
HGNCHGNC:11714
MGIMGI:101876
EntrezGene (human)GeneID:7003
(SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)TEAD1_HUMAN
UniProt ID (mouse)TEAD1_MOUSE
UniProt AC (human)P28347
(TFClass)
UniProt AC (mouse)P30051
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 12 human, 5 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
0151.069.075.0104.0
02151.57.5131.58.5
0359.0231.03.06.0
04292.01.00.06.0
051.05.00.0293.0
068.03.06.0282.0
070.0286.03.010.0
084.0254.02.039.0
09101.023.032.0143.0
1064.071.073.091.0
11148.08.0136.07.0
1267.0229.03.00.0
13297.00.02.00.0
140.00.00.0299.0
1513.00.06.0280.0
161.0294.00.04.0
174.0263.00.032.0
18133.2551.2539.2575.25
19100.581.541.575.5
PFM
ACGT
010.1710.2310.2510.348
020.5070.0250.440.028
030.1970.7730.010.02
040.9770.0030.00.02
050.0030.0170.00.98
060.0270.010.020.943
070.00.9570.010.033
080.0130.8490.0070.13
090.3380.0770.1070.478
100.2140.2370.2440.304
110.4950.0270.4550.023
120.2240.7660.010.0
130.9930.00.0070.0
140.00.00.01.0
150.0430.00.020.936
160.0030.9830.00.013
170.0130.880.00.107
180.4460.1710.1310.252
190.3360.2730.1390.253
PWM
ACGT
01-0.374-0.0780.0030.325
020.697-2.1440.557-2.038
03-0.2321.116-2.846-2.328
041.349-3.447-3.979-2.328
05-3.447-2.473-3.9791.352
06-2.09-2.846-2.3281.314
07-3.9791.328-2.846-1.897
08-2.6421.21-3.102-0.634
090.296-1.137-0.8240.64
10-0.152-0.05-0.0230.193
110.674-2.090.59-2.202
12-0.1071.107-2.846-3.979
131.365-3.979-3.102-3.979
14-3.979-3.979-3.9791.372
15-1.664-3.979-2.3281.307
16-3.4471.355-3.979-2.642
17-2.6421.245-3.979-0.824
180.57-0.369-0.6270.007
190.2910.085-0.5740.01
Standard thresholds
P-value Threshold
0.001 -0.38259
0.0005 1.11111
0.0001 4.27956