MotifTEAD1.H12CORE.1.P.C
Gene (human)TEAD1
(GeneCards)
Gene synonyms (human)TCF13, TEF1
Gene (mouse)Tead1
Gene synonyms (mouse)Tcf13, Tef-1, Tef1
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
C
Motif length13
ConsensusRMATTCCWddvWK
GC content37.25%
Information content (bits; total / per base)11.484 / 0.883
Data sourcesChIP-Seq
Aligned words1000

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 12 (82) 0.85 0.904 0.742 0.833 0.859 0.91 3.083 4.003 261.927 544.252
Mouse 5 (31) 0.831 0.903 0.717 0.827 0.806 0.884 2.612 3.434 319.959 594.328

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.854 0.827 0.793 0.771 0.743 0.726
best 0.964 0.939 0.946 0.916 0.911 0.877
Methyl HT-SELEX, 1 experiments median 0.964 0.939 0.946 0.916 0.911 0.877
best 0.964 0.939 0.946 0.916 0.911 0.877
Non-Methyl HT-SELEX, 3 experiments median 0.749 0.722 0.646 0.635 0.581 0.584
best 0.959 0.932 0.94 0.907 0.905 0.868

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 17.02 3.625 0.274 0.131

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.796 0.556 0.815 0.589
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classTEA domain factors {3.6} (TFClass)
TF familyTEF1-related {3.6.1} (TFClass)
TF subfamily {3.6.1.0} (TFClass)
TFClass IDTFClass: 3.6.1.0.1
HGNCHGNC:11714
MGIMGI:101876
EntrezGene (human)GeneID:7003
(SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)TEAD1_HUMAN
UniProt ID (mouse)TEAD1_MOUSE
UniProt AC (human)P28347
(TFClass)
UniProt AC (mouse)P30051
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 12 human, 5 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
01610.021.0315.054.0
02290.0666.037.07.0
03979.06.04.011.0
043.06.06.0985.0
0573.08.047.0872.0
064.0873.042.081.0
0713.0665.00.0322.0
08325.058.014.0603.0
09181.0166.0385.0268.0
10322.0119.0418.0141.0
11269.0475.0187.069.0
12709.055.073.0163.0
1398.061.0135.0706.0
PFM
ACGT
010.610.0210.3150.054
020.290.6660.0370.007
030.9790.0060.0040.011
040.0030.0060.0060.985
050.0730.0080.0470.872
060.0040.8730.0420.081
070.0130.6650.00.322
080.3250.0580.0140.603
090.1810.1660.3850.268
100.3220.1190.4180.141
110.2690.4750.1870.069
120.7090.0550.0730.163
130.0980.0610.1350.706
PWM
ACGT
010.888-2.4050.23-1.508
020.1470.976-1.872-3.362
031.36-3.484-3.783-2.985
04-3.975-3.484-3.4841.366
05-1.215-3.253-1.6421.244
06-3.7831.246-1.75-1.113
07-2.8390.974-4.9820.252
080.261-1.439-2.7730.876
09-0.32-0.4060.4290.069
100.252-0.7350.511-0.567
110.0730.639-0.288-1.27
121.038-1.49-1.215-0.424
13-0.926-1.39-0.611.034
Standard thresholds
P-value Threshold
0.001 4.34586
0.0005 5.32116
0.0001 7.28256