MotifTCF21.H12INVIVO.1.SM.B
Gene (human)TCF21
(GeneCards)
Gene synonyms (human)BHLHA23, POD1
Gene (mouse)Tcf21
Gene synonyms (mouse)Pod1
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length12
ConsensusndvCATATGGYv
GC content44.38%
Information content (bits; total / per base)14.166 / 1.18
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words4519

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 3 (9) 0.816 0.826 0.593 0.612 0.693 0.702 1.586 1.632 85.31 105.77

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 5 experiments median 0.883 0.837 0.799 0.76 0.692 0.679
best 0.995 0.993 0.947 0.939 0.792 0.807
Methyl HT-SELEX, 1 experiments median 0.995 0.993 0.947 0.939 0.792 0.807
best 0.995 0.993 0.947 0.939 0.792 0.807
Non-Methyl HT-SELEX, 4 experiments median 0.807 0.776 0.711 0.691 0.629 0.627
best 0.966 0.955 0.902 0.881 0.774 0.771

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.767 0.283 0.802 0.458
TF superclassBasic domains {1} (TFClass)
TF classBasic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF familyTal-related {1.2.3} (TFClass)
TF subfamilyMESP {1.2.3.3} (TFClass)
TFClass IDTFClass: 1.2.3.3.5
HGNCHGNC:11632
MGIMGI:1202715
EntrezGene (human)GeneID:6943
(SSTAR profile)
EntrezGene (mouse)GeneID:21412
(SSTAR profile)
UniProt ID (human)TCF21_HUMAN
UniProt ID (mouse)TCF21_MOUSE
UniProt AC (human)O43680
(TFClass)
UniProt AC (mouse)O35437
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 3 human, 0 mouse
HT-SELEX 4
Methyl-HT-SELEX 1
PCM
ACGT
01816.01072.01306.01325.0
021825.75451.751544.75696.75
031873.01383.01088.0175.0
040.04519.00.00.0
054453.00.066.00.0
060.00.0178.04341.0
074361.0158.00.00.0
080.00.00.04519.0
090.00.04519.00.0
100.00.03667.0852.0
11124.01427.048.02920.0
121098.75852.751785.75781.75
PFM
ACGT
010.1810.2370.2890.293
020.4040.10.3420.154
030.4140.3060.2410.039
040.01.00.00.0
050.9850.00.0150.0
060.00.00.0390.961
070.9650.0350.00.0
080.00.00.01.0
090.00.01.00.0
100.00.00.8110.189
110.0270.3160.0110.646
120.2430.1890.3950.173
PWM
ACGT
01-0.325-0.0520.1450.159
020.479-0.9140.312-0.482
030.5050.202-0.038-1.855
04-6.2881.385-6.288-6.288
051.37-6.288-2.811-6.288
06-6.288-6.288-1.8381.345
071.349-1.956-6.288-6.288
08-6.288-6.288-6.2881.385
09-6.288-6.2881.385-6.288
10-6.288-6.2881.176-0.282
11-2.1950.233-3.1180.948
12-0.028-0.2810.457-0.367
Standard thresholds
P-value Threshold
0.001 1.335055
0.0005 2.820385
0.0001 6.645225