MotifTCF21.H12INVIVO.0.PS.A
Gene (human)TCF21
(GeneCards)
Gene synonyms (human)BHLHA23, POD1
Gene (mouse)Tcf21
Gene synonyms (mouse)Pod1
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
A
Motif length12
ConsensusdvvvCAGCTGSv
GC content57.32%
Information content (bits; total / per base)12.263 / 1.022
Data sourcesChIP-Seq + HT-SELEX
Aligned words1000

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 3 (9) 0.928 0.934 0.857 0.864 0.896 0.902 3.281 3.356 557.0 712.854

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 5 experiments median 0.872 0.826 0.777 0.741 0.67 0.662
best 0.924 0.891 0.872 0.831 0.739 0.732
Methyl HT-SELEX, 1 experiments median 0.924 0.891 0.872 0.831 0.739 0.732
best 0.924 0.891 0.872 0.831 0.739 0.732
Non-Methyl HT-SELEX, 4 experiments median 0.793 0.753 0.697 0.674 0.619 0.615
best 0.899 0.861 0.836 0.793 0.72 0.706

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.708 0.135 0.762 0.463
TF superclassBasic domains {1} (TFClass)
TF classBasic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF familyTal-related {1.2.3} (TFClass)
TF subfamilyMESP {1.2.3.3} (TFClass)
TFClass IDTFClass: 1.2.3.3.5
HGNCHGNC:11632
MGIMGI:1202715
EntrezGene (human)GeneID:6943
(SSTAR profile)
EntrezGene (mouse)GeneID:21412
(SSTAR profile)
UniProt ID (human)TCF21_HUMAN
UniProt ID (mouse)TCF21_MOUSE
UniProt AC (human)O43680
(TFClass)
UniProt AC (mouse)O35437
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 3 human, 0 mouse
HT-SELEX 4
Methyl-HT-SELEX 1
PCM
ACGT
01372.0126.0355.0147.0
02381.0191.0299.0129.0
03557.0197.0200.046.0
04516.0200.0227.057.0
051.0998.01.00.0
06995.00.02.03.0
0724.013.0878.085.0
0864.0920.010.06.0
098.03.01.0988.0
103.01.0983.013.0
118.0192.0642.0158.0
12401.0192.0247.0160.0
PFM
ACGT
010.3720.1260.3550.147
020.3810.1910.2990.129
030.5570.1970.20.046
040.5160.20.2270.057
050.0010.9980.0010.0
060.9950.00.0020.003
070.0240.0130.8780.085
080.0640.920.010.006
090.0080.0030.0010.988
100.0030.0010.9830.013
110.0080.1920.6420.158
120.4010.1920.2470.16
PWM
ACGT
010.395-0.6780.349-0.526
020.419-0.2670.178-0.655
030.797-0.236-0.221-1.663
040.721-0.221-0.096-1.455
05-4.5251.379-4.525-4.982
061.376-4.982-4.213-3.975
07-2.281-2.8391.251-1.066
08-1.3431.298-3.066-3.484
09-3.253-3.975-4.5251.369
10-3.975-4.5251.364-2.839
11-3.253-0.2620.939-0.455
120.47-0.262-0.012-0.442
Standard thresholds
P-value Threshold
0.001 3.80826
0.0005 4.941985
0.0001 7.439305