MotifTBXT.H12INVITRO.1.PSM.A
Gene (human)TBXT
(GeneCards)
Gene synonyms (human)T
Gene (mouse)Tbxt
Gene synonyms (mouse)T
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
A
Motif length12
ConsensusnRbGTGYKAddd
GC content44.49%
Information content (bits; total / per base)10.118 / 0.843
Data sourcesChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words9117

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 2 (14) 0.758 0.793 0.626 0.667 0.761 0.804 2.246 2.467 55.513 97.222
Mouse 6 (36) 0.725 0.831 0.606 0.722 0.715 0.808 2.17 2.823 90.206 205.229

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 6 experiments median 0.983 0.972 0.972 0.957 0.949 0.928
best 0.999 0.998 0.997 0.996 0.993 0.99
Methyl HT-SELEX, 2 experiments median 0.987 0.978 0.978 0.966 0.962 0.946
best 0.998 0.997 0.996 0.994 0.991 0.988
Non-Methyl HT-SELEX, 4 experiments median 0.976 0.969 0.895 0.891 0.817 0.822
best 0.999 0.998 0.997 0.996 0.993 0.99
TF superclassImmunoglobulin fold {6} (TFClass)
TF classT-Box factors {6.5} (TFClass)
TF familyBrachyury-related {6.5.1} (TFClass)
TF subfamily {6.5.1.0} (TFClass)
TFClass IDTFClass: 6.5.1.0.1
HGNCHGNC:11515
MGIMGI:98472
EntrezGene (human)GeneID:6862
(SSTAR profile)
EntrezGene (mouse)GeneID:20997
(SSTAR profile)
UniProt ID (human)TBXT_HUMAN
UniProt ID (mouse)TBXT_MOUSE
UniProt AC (human)O15178
(TFClass)
UniProt AC (mouse)P20293
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 2 human, 6 mouse
HT-SELEX 4
Methyl-HT-SELEX 2
PCM
ACGT
012400.751507.752136.753071.75
025773.5393.51780.51169.5
03970.01751.05328.01068.0
041089.039.07931.058.0
050.01091.00.08026.0
060.00.09117.00.0
07417.02022.014.06664.0
0878.0519.06587.01933.0
098956.06.0151.04.0
104851.01178.01323.01765.0
114052.751329.751754.751979.75
122384.01257.01461.04015.0
PFM
ACGT
010.2630.1650.2340.337
020.6330.0430.1950.128
030.1060.1920.5840.117
040.1190.0040.870.006
050.00.120.00.88
060.00.01.00.0
070.0460.2220.0020.731
080.0090.0570.7220.212
090.9820.0010.0170.0
100.5320.1290.1450.194
110.4450.1460.1920.217
120.2610.1380.160.44
PWM
ACGT
010.052-0.413-0.0640.298
020.929-1.752-0.247-0.666
03-0.853-0.2630.849-0.757
04-0.737-4.0121.246-3.634
05-6.909-0.736-6.9091.258
06-6.909-6.9091.386-6.909
07-1.694-0.12-4.9431.072
08-3.347-1.4761.061-0.165
091.368-5.619-2.7-5.895
100.755-0.659-0.543-0.255
110.575-0.538-0.261-0.141
120.045-0.594-0.4440.566
Standard thresholds
P-value Threshold
0.001 4.88776
0.0005 5.785565
0.0001 7.424145