| Motif | TBXT.H12INVITRO.0.PS.A |
| Gene (human) | TBXT (GeneCards) |
| Gene synonyms (human) | T |
| Gene (mouse) | Tbxt |
| Gene synonyms (mouse) | T |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | A |
| Motif | TBXT.H12INVITRO.0.PS.A |
| Gene (human) | TBXT (GeneCards) |
| Gene synonyms (human) | T |
| Gene (mouse) | Tbxt |
| Gene synonyms (mouse) | T |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | A |
| Motif length | 20 |
| Consensus | YvRCAYvWRbGTGTGAWhhh |
| GC content | 44.56% |
| Information content (bits; total / per base) | 17.872 / 0.894 |
| Data sources | ChIP-Seq + HT-SELEX |
| Aligned words | 7736 |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | 2 (14) | 0.789 | 0.81 | 0.685 | 0.705 | 0.764 | 0.812 | 2.767 | 2.97 | 98.355 | 139.444 |
| Mouse | 6 (36) | 0.775 | 0.924 | 0.707 | 0.872 | 0.756 | 0.914 | 3.001 | 4.499 | 163.148 | 381.721 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 6 experiments | median | 0.997 | 0.996 | 0.993 | 0.99 | 0.976 | 0.97 |
| best | 1.0 | 0.999 | 0.998 | 0.997 | 0.988 | 0.985 | |
| Methyl HT-SELEX, 2 experiments | median | 0.998 | 0.996 | 0.993 | 0.99 | 0.98 | 0.973 |
| best | 0.999 | 0.998 | 0.994 | 0.992 | 0.983 | 0.976 | |
| Non-Methyl HT-SELEX, 4 experiments | median | 0.994 | 0.994 | 0.896 | 0.904 | 0.816 | 0.83 |
| best | 1.0 | 0.999 | 0.998 | 0.997 | 0.988 | 0.985 | |
| TF superclass | Immunoglobulin fold {6} (TFClass) |
| TF class | T-Box factors {6.5} (TFClass) |
| TF family | Brachyury-related {6.5.1} (TFClass) |
| TF subfamily | {6.5.1.0} (TFClass) |
| TFClass ID | TFClass: 6.5.1.0.1 |
| HGNC | HGNC:11515 |
| MGI | MGI:98472 |
| EntrezGene (human) | GeneID:6862 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:20997 (SSTAR profile) |
| UniProt ID (human) | TBXT_HUMAN |
| UniProt ID (mouse) | TBXT_MOUSE |
| UniProt AC (human) | O15178 (TFClass) |
| UniProt AC (mouse) | P20293 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 2 human, 6 mouse |
| HT-SELEX | 4 |
| Methyl-HT-SELEX | 2 |
| PCM | TBXT.H12INVITRO.0.PS.A.pcm |
| PWM | TBXT.H12INVITRO.0.PS.A.pwm |
| PFM | TBXT.H12INVITRO.0.PS.A.pfm |
| Alignment | TBXT.H12INVITRO.0.PS.A.words.tsv |
| Threshold to P-value map | TBXT.H12INVITRO.0.PS.A.thr |
| Motif in other formats | |
| JASPAR format | TBXT.H12INVITRO.0.PS.A_jaspar_format.txt |
| MEME format | TBXT.H12INVITRO.0.PS.A_meme_format.meme |
| Transfac format | TBXT.H12INVITRO.0.PS.A_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 497.75 | 682.75 | 529.75 | 6025.75 |
| 02 | 2335.5 | 2988.5 | 1858.5 | 553.5 |
| 03 | 4240.0 | 94.0 | 2802.0 | 600.0 |
| 04 | 120.0 | 7352.0 | 113.0 | 151.0 |
| 05 | 6669.0 | 87.0 | 866.0 | 114.0 |
| 06 | 512.0 | 5081.0 | 391.0 | 1752.0 |
| 07 | 1914.0 | 2901.0 | 2006.0 | 915.0 |
| 08 | 681.0 | 519.0 | 498.0 | 6038.0 |
| 09 | 6041.0 | 147.0 | 896.0 | 652.0 |
| 10 | 808.0 | 1002.0 | 4436.0 | 1490.0 |
| 11 | 687.0 | 44.0 | 6877.0 | 128.0 |
| 12 | 12.0 | 153.0 | 20.0 | 7551.0 |
| 13 | 16.0 | 1.0 | 7712.0 | 7.0 |
| 14 | 222.0 | 1144.0 | 33.0 | 6337.0 |
| 15 | 103.0 | 375.0 | 6045.0 | 1213.0 |
| 16 | 7645.0 | 20.0 | 44.0 | 27.0 |
| 17 | 5127.0 | 773.0 | 505.0 | 1331.0 |
| 18 | 3139.0 | 2123.0 | 646.0 | 1828.0 |
| 19 | 1559.5 | 2304.5 | 646.5 | 3225.5 |
| 20 | 1353.25 | 2966.25 | 1254.25 | 2162.25 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.064 | 0.088 | 0.068 | 0.779 |
| 02 | 0.302 | 0.386 | 0.24 | 0.072 |
| 03 | 0.548 | 0.012 | 0.362 | 0.078 |
| 04 | 0.016 | 0.95 | 0.015 | 0.02 |
| 05 | 0.862 | 0.011 | 0.112 | 0.015 |
| 06 | 0.066 | 0.657 | 0.051 | 0.226 |
| 07 | 0.247 | 0.375 | 0.259 | 0.118 |
| 08 | 0.088 | 0.067 | 0.064 | 0.781 |
| 09 | 0.781 | 0.019 | 0.116 | 0.084 |
| 10 | 0.104 | 0.13 | 0.573 | 0.193 |
| 11 | 0.089 | 0.006 | 0.889 | 0.017 |
| 12 | 0.002 | 0.02 | 0.003 | 0.976 |
| 13 | 0.002 | 0.0 | 0.997 | 0.001 |
| 14 | 0.029 | 0.148 | 0.004 | 0.819 |
| 15 | 0.013 | 0.048 | 0.781 | 0.157 |
| 16 | 0.988 | 0.003 | 0.006 | 0.003 |
| 17 | 0.663 | 0.1 | 0.065 | 0.172 |
| 18 | 0.406 | 0.274 | 0.084 | 0.236 |
| 19 | 0.202 | 0.298 | 0.084 | 0.417 |
| 20 | 0.175 | 0.383 | 0.162 | 0.28 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -1.354 | -1.039 | -1.292 | 1.136 |
| 02 | 0.188 | 0.435 | -0.04 | -1.248 |
| 03 | 0.784 | -3.002 | 0.37 | -1.168 |
| 04 | -2.763 | 1.335 | -2.821 | -2.537 |
| 05 | 1.237 | -3.077 | -0.802 | -2.813 |
| 06 | -1.326 | 0.965 | -1.594 | -0.099 |
| 07 | -0.01 | 0.405 | 0.037 | -0.747 |
| 08 | -1.042 | -1.312 | -1.353 | 1.138 |
| 09 | 1.138 | -2.563 | -0.768 | -1.085 |
| 10 | -0.871 | -0.657 | 0.83 | -0.26 |
| 11 | -1.033 | -3.735 | 1.268 | -2.699 |
| 12 | -4.913 | -2.524 | -4.467 | 1.361 |
| 13 | -4.665 | -6.393 | 1.382 | -5.345 |
| 14 | -2.156 | -0.524 | -4.006 | 1.186 |
| 15 | -2.912 | -1.636 | 1.139 | -0.466 |
| 16 | 1.374 | -4.467 | -3.735 | -4.193 |
| 17 | 0.974 | -0.915 | -1.34 | -0.373 |
| 18 | 0.484 | 0.093 | -1.094 | -0.056 |
| 19 | -0.215 | 0.175 | -1.093 | 0.511 |
| 20 | -0.357 | 0.427 | -0.432 | 0.111 |
| P-value | Threshold |
|---|---|
| 0.001 | 1.40666 |
| 0.0005 | 2.76441 |
| 0.0001 | 5.59886 |