| Motif | TBX5.H12INVIVO.0.PS.A |
| Gene (human) | TBX5 (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Tbx5 |
| Gene synonyms (mouse) | |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | A |
| Motif | TBX5.H12INVIVO.0.PS.A |
| Gene (human) | TBX5 (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Tbx5 |
| Gene synonyms (mouse) | |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | A |
| Motif length | 9 |
| Consensus | vRRGTGYbd |
| GC content | 54.35% |
| Information content (bits; total / per base) | 7.502 / 0.834 |
| Data sources | ChIP-Seq + HT-SELEX |
| Aligned words | 1001 |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | 8 (52) | 0.746 | 0.775 | 0.568 | 0.61 | 0.64 | 0.672 | 1.471 | 1.607 | 68.707 | 92.658 |
| Mouse | 9 (57) | 0.855 | 0.927 | 0.732 | 0.831 | 0.799 | 0.891 | 2.341 | 3.095 | 127.137 | 207.174 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Non-Methyl HT-SELEX, 2 experiments | median | 0.742 | 0.717 | 0.649 | 0.635 | 0.594 | 0.589 |
| best | 0.805 | 0.784 | 0.684 | 0.675 | 0.616 | 0.614 | |
| TF superclass | Immunoglobulin fold {6} (TFClass) |
| TF class | T-Box factors {6.5} (TFClass) |
| TF family | TBX2-related {6.5.4} (TFClass) |
| TF subfamily | {6.5.4.0} (TFClass) |
| TFClass ID | TFClass: 6.5.4.0.4 |
| HGNC | HGNC:11604 |
| MGI | MGI:102541 |
| EntrezGene (human) | GeneID:6910 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:21388 (SSTAR profile) |
| UniProt ID (human) | TBX5_HUMAN |
| UniProt ID (mouse) | TBX5_MOUSE |
| UniProt AC (human) | Q99593 (TFClass) |
| UniProt AC (mouse) | P70326 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 8 human, 9 mouse |
| HT-SELEX | 2 |
| Methyl-HT-SELEX | 0 |
| PCM | TBX5.H12INVIVO.0.PS.A.pcm |
| PWM | TBX5.H12INVIVO.0.PS.A.pwm |
| PFM | TBX5.H12INVIVO.0.PS.A.pfm |
| Alignment | TBX5.H12INVIVO.0.PS.A.words.tsv |
| Threshold to P-value map | TBX5.H12INVIVO.0.PS.A.thr |
| Motif in other formats | |
| JASPAR format | TBX5.H12INVIVO.0.PS.A_jaspar_format.txt |
| MEME format | TBX5.H12INVIVO.0.PS.A_meme_format.meme |
| Transfac format | TBX5.H12INVIVO.0.PS.A_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 306.0 | 159.0 | 385.0 | 151.0 |
| 02 | 677.0 | 23.0 | 219.0 | 82.0 |
| 03 | 183.0 | 27.0 | 738.0 | 53.0 |
| 04 | 6.0 | 131.0 | 858.0 | 6.0 |
| 05 | 13.0 | 78.0 | 9.0 | 901.0 |
| 06 | 7.0 | 4.0 | 986.0 | 4.0 |
| 07 | 134.0 | 170.0 | 74.0 | 623.0 |
| 08 | 13.0 | 418.0 | 304.0 | 266.0 |
| 09 | 508.0 | 50.0 | 263.0 | 180.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.306 | 0.159 | 0.385 | 0.151 |
| 02 | 0.676 | 0.023 | 0.219 | 0.082 |
| 03 | 0.183 | 0.027 | 0.737 | 0.053 |
| 04 | 0.006 | 0.131 | 0.857 | 0.006 |
| 05 | 0.013 | 0.078 | 0.009 | 0.9 |
| 06 | 0.007 | 0.004 | 0.985 | 0.004 |
| 07 | 0.134 | 0.17 | 0.074 | 0.622 |
| 08 | 0.013 | 0.418 | 0.304 | 0.266 |
| 09 | 0.507 | 0.05 | 0.263 | 0.18 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.2 | -0.45 | 0.428 | -0.501 |
| 02 | 0.991 | -2.321 | -0.132 | -1.102 |
| 03 | -0.31 | -2.171 | 1.077 | -1.527 |
| 04 | -3.485 | -0.641 | 1.227 | -3.485 |
| 05 | -2.84 | -1.151 | -3.157 | 1.276 |
| 06 | -3.363 | -3.784 | 1.366 | -3.784 |
| 07 | -0.619 | -0.383 | -1.202 | 0.908 |
| 08 | -2.84 | 0.51 | 0.193 | 0.061 |
| 09 | 0.705 | -1.583 | 0.049 | -0.327 |
| P-value | Threshold |
|---|---|
| 0.001 | 5.18078 |
| 0.0005 | 5.842455 |
| 0.0001 | 6.992235 |