MotifTBX5.H12INVITRO.2.S.B
Gene (human)TBX5
(GeneCards)
Gene synonyms (human)
Gene (mouse)Tbx5
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype2
Quality
B
Motif length26
ConsensusnnbdRAGGTGTKAndddhvRMRYYYn
GC content45.66%
Information content (bits; total / per base)19.813 / 0.762
Data sourcesHT-SELEX
Aligned words269

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 8 (52) 0.609 0.641 0.415 0.439 0.574 0.599 1.25 1.36 13.0 26.409
Mouse 9 (57) 0.728 0.842 0.578 0.75 0.68 0.8 1.904 3.004 43.658 109.119

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Non-Methyl HT-SELEX, 2 experiments median 0.743 0.733 0.645 0.64 0.587 0.589
best 0.811 0.805 0.688 0.685 0.613 0.618
TF superclassImmunoglobulin fold {6} (TFClass)
TF classT-Box factors {6.5} (TFClass)
TF familyTBX2-related {6.5.4} (TFClass)
TF subfamily {6.5.4.0} (TFClass)
TFClass IDTFClass: 6.5.4.0.4
HGNCHGNC:11604
MGIMGI:102541
EntrezGene (human)GeneID:6910
(SSTAR profile)
EntrezGene (mouse)GeneID:21388
(SSTAR profile)
UniProt ID (human)TBX5_HUMAN
UniProt ID (mouse)TBX5_MOUSE
UniProt AC (human)Q99593
(TFClass)
UniProt AC (mouse)P70326
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 8 human, 9 mouse
HT-SELEX 2
Methyl-HT-SELEX 0
PCM
ACGT
0145.2564.2598.2561.25
0276.548.590.553.5
0322.066.0118.063.0
0493.027.066.083.0
05162.04.061.042.0
06264.00.05.00.0
070.01.0268.00.0
080.00.0269.00.0
090.00.01.0268.0
100.00.0269.00.0
115.02.09.0253.0
121.011.0164.093.0
13244.06.08.011.0
1476.052.057.084.0
15157.024.047.041.0
1692.010.046.0121.0
1762.028.075.0104.0
1846.037.030.0156.0
1997.098.049.025.0
20175.030.034.030.0
2136.0199.023.011.0
22183.033.037.016.0
2321.0201.023.024.0
247.0165.042.055.0
2524.540.530.5173.5
2659.080.046.084.0
PFM
ACGT
010.1680.2390.3650.228
020.2840.180.3360.199
030.0820.2450.4390.234
040.3460.10.2450.309
050.6020.0150.2270.156
060.9810.00.0190.0
070.00.0040.9960.0
080.00.01.00.0
090.00.00.0040.996
100.00.01.00.0
110.0190.0070.0330.941
120.0040.0410.610.346
130.9070.0220.030.041
140.2830.1930.2120.312
150.5840.0890.1750.152
160.3420.0370.1710.45
170.230.1040.2790.387
180.1710.1380.1120.58
190.3610.3640.1820.093
200.6510.1120.1260.112
210.1340.740.0860.041
220.680.1230.1380.059
230.0780.7470.0860.089
240.0260.6130.1560.204
250.0910.1510.1130.645
260.2190.2970.1710.312
PWM
ACGT
01-0.386-0.0450.373-0.091
020.126-0.3190.292-0.224
03-1.076-0.0180.553-0.064
040.319-0.883-0.0180.207
050.867-2.543-0.095-0.459
061.352-3.893-2.373-3.893
07-3.893-3.3541.367-3.893
08-3.893-3.8931.371-3.893
09-3.893-3.893-3.3541.367
10-3.893-3.8931.371-3.893
11-2.373-3.006-1.8871.31
12-3.354-1.7110.8790.319
131.274-2.228-1.988-1.711
140.12-0.251-0.1620.218
150.836-0.994-0.35-0.482
160.308-1.796-0.370.578
17-0.08-0.8480.1070.429
18-0.37-0.581-0.7820.83
190.360.37-0.309-0.956
200.944-0.782-0.662-0.782
21-0.6071.071-1.034-1.711
220.988-0.691-0.581-1.373
23-1.121.081-1.034-0.994
24-2.1010.885-0.459-0.197
25-0.975-0.494-0.7660.935
26-0.1280.17-0.370.218
Standard thresholds
P-value Threshold
0.001 0.99816
0.0005 2.36791
0.0001 5.25871