TBX5.H12CORE.1.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	TBX5.H12CORE.1.P.B
Gene (human)	TBX5 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Tbx5
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	13
Consensus	ddSWGnTGAMAKv
GC content	52.85%
Information content (bits; total / per base)	10.513 / 0.809
Data sources	ChIP-Seq
Aligned words	1000

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	8 (52)	0.83	0.868	0.724	0.775	0.789	0.822	2.581	2.845	116.704	172.678
Mouse	9 (57)	0.681	0.816	0.519	0.718	0.65	0.779	1.695	2.642	23.921	113.18

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 2 experiments	median	0.512	0.505	0.514	0.507	0.514	0.507
Non-Methyl HT-SELEX, 2 experiments	best	0.516	0.508	0.52	0.509	0.521	0.51

TF superclass	Immunoglobulin fold {6} (TFClass)
TF class	T-Box factors {6.5} (TFClass)
TF family	TBX2-related {6.5.4} (TFClass)
TF subfamily	{6.5.4.0} (TFClass)
TFClass ID	TFClass: 6.5.4.0.4
HGNC	HGNC:11604
MGI	MGI:102541
EntrezGene (human)	GeneID:6910 (SSTAR profile)
EntrezGene (mouse)	GeneID:21388 (SSTAR profile)
UniProt ID (human)	TBX5_HUMAN
UniProt ID (mouse)	TBX5_MOUSE
UniProt AC (human)	Q99593 (TFClass)
UniProt AC (mouse)	P70326 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	8 human, 9 mouse
HT-SELEX	2
Methyl-HT-SELEX	0

PCM	TBX5.H12CORE.1.P.B.pcm
PWM	TBX5.H12CORE.1.P.B.pwm
PFM	TBX5.H12CORE.1.P.B.pfm
Alignment	TBX5.H12CORE.1.P.B.words.tsv
Threshold to P-value map	TBX5.H12CORE.1.P.B.thr
Motif in other formats
JASPAR format	TBX5.H12CORE.1.P.B_jaspar_format.txt
MEME format	TBX5.H12CORE.1.P.B_meme_format.meme
Transfac format	TBX5.H12CORE.1.P.B_transfac_format.txt
Homer format	TBX5.H12CORE.1.P.B_homer_format_0.001.txt TBX5.H12CORE.1.P.B_homer_format_0.0005.txt TBX5.H12CORE.1.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	329.0	122.0	342.0	207.0
02	335.0	93.0	423.0	149.0
03	74.0	308.0	542.0	76.0
04	167.0	43.0	47.0	743.0
05	23.0	33.0	923.0	21.0
06	213.0	355.0	226.0	206.0
07	37.0	6.0	50.0	907.0
08	21.0	4.0	971.0	4.0
09	828.0	18.0	80.0	74.0
10	144.0	720.0	101.0	35.0
11	884.0	4.0	29.0	83.0
12	109.0	26.0	740.0	125.0
13	228.0	269.0	395.0	108.0

PFM

	A	C	G	T
01	0.329	0.122	0.342	0.207
02	0.335	0.093	0.423	0.149
03	0.074	0.308	0.542	0.076
04	0.167	0.043	0.047	0.743
05	0.023	0.033	0.923	0.021
06	0.213	0.355	0.226	0.206
07	0.037	0.006	0.05	0.907
08	0.021	0.004	0.971	0.004
09	0.828	0.018	0.08	0.074
10	0.144	0.72	0.101	0.035
11	0.884	0.004	0.029	0.083
12	0.109	0.026	0.74	0.125
13	0.228	0.269	0.395	0.108

PWM

	A	C	G	T
01	0.273	-0.71	0.312	-0.187
02	0.291	-0.977	0.523	-0.513
03	-1.201	0.207	0.77	-1.175
04	-0.4	-1.728	-1.642	1.085
05	-2.32	-1.981	1.301	-2.405
06	-0.159	0.349	-0.1	-0.192
07	-1.872	-3.484	-1.582	1.284
08	-2.405	-3.783	1.352	-3.783
09	1.193	-2.546	-1.125	-1.201
10	-0.547	1.053	-0.896	-1.925
11	1.258	-3.783	-2.103	-1.089
12	-0.821	-2.206	1.081	-0.686
13	-0.091	0.073	0.455	-0.83

Standard thresholds

P-value	Threshold
0.001	4.60501
0.0005	5.46606
0.0001	7.23207