TBX5.H12CORE.0.PS.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	TBX5.H12CORE.0.PS.A
Gene (human)	TBX5 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Tbx5
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	9
Consensus	vRRGTGYbd
GC content	54.35%
Information content (bits; total / per base)	7.502 / 0.834
Data sources	ChIP-Seq + HT-SELEX
Aligned words	1001

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	8 (52)	0.746	0.775	0.568	0.61	0.64	0.672	1.471	1.607	68.707	92.658
Mouse	9 (57)	0.855	0.927	0.732	0.831	0.799	0.891	2.341	3.095	127.137	207.174

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 2 experiments	median	0.742	0.717	0.649	0.635	0.594	0.589
Non-Methyl HT-SELEX, 2 experiments	best	0.805	0.784	0.684	0.675	0.616	0.614

TF superclass	Immunoglobulin fold {6} (TFClass)
TF class	T-Box factors {6.5} (TFClass)
TF family	TBX2-related {6.5.4} (TFClass)
TF subfamily	{6.5.4.0} (TFClass)
TFClass ID	TFClass: 6.5.4.0.4
HGNC	HGNC:11604
MGI	MGI:102541
EntrezGene (human)	GeneID:6910 (SSTAR profile)
EntrezGene (mouse)	GeneID:21388 (SSTAR profile)
UniProt ID (human)	TBX5_HUMAN
UniProt ID (mouse)	TBX5_MOUSE
UniProt AC (human)	Q99593 (TFClass)
UniProt AC (mouse)	P70326 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	8 human, 9 mouse
HT-SELEX	2
Methyl-HT-SELEX	0

PCM	TBX5.H12CORE.0.PS.A.pcm
PWM	TBX5.H12CORE.0.PS.A.pwm
PFM	TBX5.H12CORE.0.PS.A.pfm
Alignment	TBX5.H12CORE.0.PS.A.words.tsv
Threshold to P-value map	TBX5.H12CORE.0.PS.A.thr
Motif in other formats
JASPAR format	TBX5.H12CORE.0.PS.A_jaspar_format.txt
MEME format	TBX5.H12CORE.0.PS.A_meme_format.meme
Transfac format	TBX5.H12CORE.0.PS.A_transfac_format.txt
Homer format	TBX5.H12CORE.0.PS.A_homer_format_0.001.txt TBX5.H12CORE.0.PS.A_homer_format_0.0005.txt TBX5.H12CORE.0.PS.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	306.0	159.0	385.0	151.0
02	677.0	23.0	219.0	82.0
03	183.0	27.0	738.0	53.0
04	6.0	131.0	858.0	6.0
05	13.0	78.0	9.0	901.0
06	7.0	4.0	986.0	4.0
07	134.0	170.0	74.0	623.0
08	13.0	418.0	304.0	266.0
09	508.0	50.0	263.0	180.0

PFM

	A	C	G	T
01	0.306	0.159	0.385	0.151
02	0.676	0.023	0.219	0.082
03	0.183	0.027	0.737	0.053
04	0.006	0.131	0.857	0.006
05	0.013	0.078	0.009	0.9
06	0.007	0.004	0.985	0.004
07	0.134	0.17	0.074	0.622
08	0.013	0.418	0.304	0.266
09	0.507	0.05	0.263	0.18

PWM

	A	C	G	T
01	0.2	-0.45	0.428	-0.501
02	0.991	-2.321	-0.132	-1.102
03	-0.31	-2.171	1.077	-1.527
04	-3.485	-0.641	1.227	-3.485
05	-2.84	-1.151	-3.157	1.276
06	-3.363	-3.784	1.366	-3.784
07	-0.619	-0.383	-1.202	0.908
08	-2.84	0.51	0.193	0.061
09	0.705	-1.583	0.049	-0.327

Standard thresholds

P-value	Threshold
0.001	5.18078
0.0005	5.842455
0.0001	6.992235