TBX20.H12CORE.0.P.C motif - HOmo sapiens COmprehensive MOdel COllection

Motif	TBX20.H12CORE.0.P.C
Gene (human)	TBX20 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Tbx20
Gene synonyms (mouse)	Tbx12
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	C

Motif length	14
Consensus	ndSYGnTGAMAKvh
GC content	52.04%
Information content (bits; total / per base)	11.249 / 0.804
Data sources	ChIP-Seq
Aligned words	793

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Mouse	1 (7)	0.873	0.909	0.832	0.877	0.842	0.882	3.46	3.907	189.495	233.699

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 6 experiments	median	0.549	0.526	0.546	0.525	0.541	0.523
Overall, 6 experiments	best	0.641	0.589	0.62	0.575	0.596	0.562
Methyl HT-SELEX, 2 experiments	median	0.544	0.525	0.535	0.52	0.529	0.517
Methyl HT-SELEX, 2 experiments	best	0.552	0.53	0.541	0.524	0.535	0.521
Non-Methyl HT-SELEX, 4 experiments	median	0.566	0.535	0.564	0.535	0.557	0.532
Non-Methyl HT-SELEX, 4 experiments	best	0.641	0.589	0.62	0.575	0.596	0.562

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.604	0.007	0.364	0.154
batch 2	0.536	0.228	0.222	0.111

TF superclass	Immunoglobulin fold {6} (TFClass)
TF class	T-Box factors {6.5} (TFClass)
TF family	TBX1-related {6.5.3} (TFClass)
TF subfamily	{6.5.3.0} (TFClass)
TFClass ID	TFClass: 6.5.3.0.5
HGNC	HGNC:11598
MGI	MGI:1888496
EntrezGene (human)	GeneID:57057 (SSTAR profile)
EntrezGene (mouse)	GeneID:57246 (SSTAR profile)
UniProt ID (human)	TBX20_HUMAN
UniProt ID (mouse)	TBX20_MOUSE
UniProt AC (human)	Q9UMR3 (TFClass)
UniProt AC (mouse)	Q9ES03 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 1 mouse
HT-SELEX	4
Methyl-HT-SELEX	2

PCM	TBX20.H12CORE.0.P.C.pcm
PWM	TBX20.H12CORE.0.P.C.pwm
PFM	TBX20.H12CORE.0.P.C.pfm
Alignment	TBX20.H12CORE.0.P.C.words.tsv
Threshold to P-value map	TBX20.H12CORE.0.P.C.thr
Motif in other formats
JASPAR format	TBX20.H12CORE.0.P.C_jaspar_format.txt
MEME format	TBX20.H12CORE.0.P.C_meme_format.meme
Transfac format	TBX20.H12CORE.0.P.C_transfac_format.txt
Homer format	TBX20.H12CORE.0.P.C_homer_format_0.001.txt TBX20.H12CORE.0.P.C_homer_format_0.0005.txt TBX20.H12CORE.0.P.C_homer_format_0.0001.txt

PCM

	A	C	G	T
01	277.0	114.0	242.0	160.0
02	208.0	95.0	376.0	114.0
03	52.0	193.0	476.0	72.0
04	61.0	86.0	17.0	629.0
05	21.0	7.0	751.0	14.0
06	178.0	232.0	142.0	241.0
07	23.0	17.0	66.0	687.0
08	30.0	3.0	741.0	19.0
09	753.0	13.0	18.0	9.0
10	127.0	580.0	61.0	25.0
11	711.0	5.0	25.0	52.0
12	88.0	23.0	584.0	98.0
13	109.0	272.0	347.0	65.0
14	225.0	207.0	85.0	276.0

PFM

	A	C	G	T
01	0.349	0.144	0.305	0.202
02	0.262	0.12	0.474	0.144
03	0.066	0.243	0.6	0.091
04	0.077	0.108	0.021	0.793
05	0.026	0.009	0.947	0.018
06	0.224	0.293	0.179	0.304
07	0.029	0.021	0.083	0.866
08	0.038	0.004	0.934	0.024
09	0.95	0.016	0.023	0.011
10	0.16	0.731	0.077	0.032
11	0.897	0.006	0.032	0.066
12	0.111	0.029	0.736	0.124
13	0.137	0.343	0.438	0.082
14	0.284	0.261	0.107	0.348

PWM

	A	C	G	T
01	0.332	-0.547	0.198	-0.212
02	0.048	-0.727	0.636	-0.547
03	-1.315	-0.027	0.871	-0.998
04	-1.16	-0.824	-2.371	1.149
05	-2.177	-3.138	1.326	-2.546
06	-0.107	0.156	-0.33	0.194
07	-2.092	-2.371	-1.083	1.237
08	-1.843	-3.757	1.312	-2.269
09	1.328	-2.612	-2.319	-2.931
10	-0.441	1.068	-1.16	-2.014
11	1.271	-3.4	-2.014	-1.315
12	-0.802	-2.092	1.075	-0.696
13	-0.591	0.314	0.556	-1.098
14	0.126	0.043	-0.836	0.329

Standard thresholds

P-value	Threshold
0.001	4.41786
0.0005	5.31956
0.0001	7.19006