| Motif | TBX2.H12CORE.0.SM.B |
| Gene (human) | TBX2 (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Tbx2 |
| Gene synonyms (mouse) | |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | B |
| Motif | TBX2.H12CORE.0.SM.B |
| Gene (human) | TBX2 (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Tbx2 |
| Gene synonyms (mouse) | |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | B |
| Motif length | 10 |
| Consensus | nRGGTGWbdn |
| GC content | 49.43% |
| Information content (bits; total / per base) | 8.605 / 0.86 |
| Data sources | HT-SELEX + Methyl-HT-SELEX |
| Aligned words | 9694 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 5 experiments | median | 0.848 | 0.807 | 0.804 | 0.742 | 0.76 | 0.704 |
| best | 0.945 | 0.914 | 0.915 | 0.876 | 0.865 | 0.824 | |
| Methyl HT-SELEX, 2 experiments | median | 0.896 | 0.849 | 0.859 | 0.809 | 0.812 | 0.764 |
| best | 0.945 | 0.914 | 0.915 | 0.876 | 0.865 | 0.824 | |
| Non-Methyl HT-SELEX, 3 experiments | median | 0.84 | 0.807 | 0.725 | 0.704 | 0.637 | 0.634 |
| best | 0.884 | 0.824 | 0.853 | 0.791 | 0.804 | 0.749 | |
| rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
|---|---|---|---|---|
| batch 1 | 0.992 | 0.539 | 0.958 | 0.651 |
| batch 2 | 0.637 | 0.213 | 0.651 | 0.465 |
| TF superclass | Immunoglobulin fold {6} (TFClass) |
| TF class | T-Box factors {6.5} (TFClass) |
| TF family | TBX2-related {6.5.4} (TFClass) |
| TF subfamily | {6.5.4.0} (TFClass) |
| TFClass ID | TFClass: 6.5.4.0.1 |
| HGNC | HGNC:11597 |
| MGI | MGI:98494 |
| EntrezGene (human) | GeneID:6909 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:21385 (SSTAR profile) |
| UniProt ID (human) | TBX2_HUMAN |
| UniProt ID (mouse) | TBX2_MOUSE |
| UniProt AC (human) | Q13207 (TFClass) |
| UniProt AC (mouse) | Q60707 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 0 human, 0 mouse |
| HT-SELEX | 3 |
| Methyl-HT-SELEX | 2 |
| PCM | TBX2.H12CORE.0.SM.B.pcm |
| PWM | TBX2.H12CORE.0.SM.B.pwm |
| PFM | TBX2.H12CORE.0.SM.B.pfm |
| Alignment | TBX2.H12CORE.0.SM.B.words.tsv |
| Threshold to P-value map | TBX2.H12CORE.0.SM.B.thr |
| Motif in other formats | |
| JASPAR format | TBX2.H12CORE.0.SM.B_jaspar_format.txt |
| MEME format | TBX2.H12CORE.0.SM.B_meme_format.meme |
| Transfac format | TBX2.H12CORE.0.SM.B_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 3486.75 | 1343.75 | 2477.75 | 2385.75 |
| 02 | 6871.0 | 501.0 | 1483.0 | 839.0 |
| 03 | 664.0 | 810.0 | 8021.0 | 199.0 |
| 04 | 36.0 | 38.0 | 9611.0 | 9.0 |
| 05 | 7.0 | 358.0 | 17.0 | 9312.0 |
| 06 | 33.0 | 5.0 | 9634.0 | 22.0 |
| 07 | 1421.0 | 691.0 | 529.0 | 7053.0 |
| 08 | 1096.0 | 2038.0 | 3172.0 | 3388.0 |
| 09 | 4918.0 | 1202.0 | 1835.0 | 1739.0 |
| 10 | 3180.25 | 1925.25 | 2221.25 | 2367.25 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.36 | 0.139 | 0.256 | 0.246 |
| 02 | 0.709 | 0.052 | 0.153 | 0.087 |
| 03 | 0.068 | 0.084 | 0.827 | 0.021 |
| 04 | 0.004 | 0.004 | 0.991 | 0.001 |
| 05 | 0.001 | 0.037 | 0.002 | 0.961 |
| 06 | 0.003 | 0.001 | 0.994 | 0.002 |
| 07 | 0.147 | 0.071 | 0.055 | 0.728 |
| 08 | 0.113 | 0.21 | 0.327 | 0.349 |
| 09 | 0.507 | 0.124 | 0.189 | 0.179 |
| 10 | 0.328 | 0.199 | 0.229 | 0.244 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.363 | -0.589 | 0.022 | -0.016 |
| 02 | 1.041 | -1.573 | -0.491 | -1.059 |
| 03 | -1.292 | -1.094 | 1.196 | -2.489 |
| 04 | -4.149 | -4.098 | 1.377 | -5.37 |
| 05 | -5.564 | -1.907 | -4.834 | 1.345 |
| 06 | -4.23 | -5.807 | 1.379 | -4.604 |
| 07 | -0.533 | -1.252 | -1.519 | 1.068 |
| 08 | -0.792 | -0.173 | 0.269 | 0.335 |
| 09 | 0.707 | -0.7 | -0.278 | -0.332 |
| 10 | 0.272 | -0.23 | -0.087 | -0.023 |
| P-value | Threshold |
|---|---|
| 0.001 | 5.174765 |
| 0.0005 | 5.89494 |
| 0.0001 | 7.29012 |