TBX15.H12RSNP.0.SM.D motif - HOmo sapiens COmprehensive MOdel COllection

Motif	TBX15.H12RSNP.0.SM.D
Gene (human)	TBX15 (GeneCards)
Gene synonyms (human)	TBX14
Gene (mouse)	Tbx15
Gene synonyms (mouse)	Tbx14, Tbx8
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	D

Motif length	13
Consensus	ndAGGTGTbAdnn
GC content	49.98%
Information content (bits; total / per base)	11.139 / 0.857
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	8404

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.971	0.953	0.949	0.924	0.914	0.883
Overall, 2 experiments	best	0.974	0.956	0.956	0.933	0.924	0.895
Methyl HT-SELEX, 1 experiments	median	0.968	0.95	0.942	0.916	0.903	0.87
Methyl HT-SELEX, 1 experiments	best	0.968	0.95	0.942	0.916	0.903	0.87
Non-Methyl HT-SELEX, 1 experiments	median	0.974	0.956	0.956	0.933	0.924	0.895
Non-Methyl HT-SELEX, 1 experiments	best	0.974	0.956	0.956	0.933	0.924	0.895

TF superclass	Immunoglobulin fold {6} (TFClass)
TF class	T-Box factors {6.5} (TFClass)
TF family	TBX1-related {6.5.3} (TFClass)
TF subfamily	{6.5.3.0} (TFClass)
TFClass ID	TFClass: 6.5.3.0.3
HGNC	HGNC:11594
MGI	MGI:1277234
EntrezGene (human)	GeneID:6913 (SSTAR profile)
EntrezGene (mouse)	GeneID:21384 (SSTAR profile)
UniProt ID (human)	TBX15_HUMAN
UniProt ID (mouse)	TBX15_MOUSE
UniProt AC (human)	Q96SF7 (TFClass)
UniProt AC (mouse)	O70306 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	TBX15.H12RSNP.0.SM.D.pcm
PWM	TBX15.H12RSNP.0.SM.D.pwm
PFM	TBX15.H12RSNP.0.SM.D.pfm
Alignment	TBX15.H12RSNP.0.SM.D.words.tsv
Threshold to P-value map	TBX15.H12RSNP.0.SM.D.thr
Motif in other formats
JASPAR format	TBX15.H12RSNP.0.SM.D_jaspar_format.txt
MEME format	TBX15.H12RSNP.0.SM.D_meme_format.meme
Transfac format	TBX15.H12RSNP.0.SM.D_transfac_format.txt
Homer format	TBX15.H12RSNP.0.SM.D_homer_format_0.001.txt TBX15.H12RSNP.0.SM.D_homer_format_0.0005.txt TBX15.H12RSNP.0.SM.D_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1787.5	1679.5	2259.5	2677.5
02	3336.0	677.0	2375.0	2016.0
03	6703.0	66.0	1054.0	581.0
04	99.0	291.0	8000.0	14.0
05	1.0	0.0	8403.0	0.0
06	0.0	2046.0	0.0	6358.0
07	0.0	0.0	8404.0	0.0
08	754.0	570.0	52.0	7028.0
09	140.0	1882.0	3916.0	2466.0
10	7027.0	31.0	1172.0	174.0
11	3423.0	1372.0	1573.0	2036.0
12	2218.75	1663.75	3113.75	1407.75
13	1869.0	1152.0	2856.0	2527.0

PFM

	A	C	G	T
01	0.213	0.2	0.269	0.319
02	0.397	0.081	0.283	0.24
03	0.798	0.008	0.125	0.069
04	0.012	0.035	0.952	0.002
05	0.0	0.0	1.0	0.0
06	0.0	0.243	0.0	0.757
07	0.0	0.0	1.0	0.0
08	0.09	0.068	0.006	0.836
09	0.017	0.224	0.466	0.293
10	0.836	0.004	0.139	0.021
11	0.407	0.163	0.187	0.242
12	0.264	0.198	0.371	0.168
13	0.222	0.137	0.34	0.301

PWM

	A	C	G	T
01	-0.161	-0.224	0.073	0.242
02	0.462	-1.13	0.122	-0.041
03	1.159	-3.428	-0.689	-1.283
04	-3.034	-1.97	1.336	-4.863
05	-6.47	-6.836	1.385	-6.836
06	-6.836	-0.026	-6.836	1.107
07	-6.836	-6.836	1.385	-6.836
08	-1.023	-1.302	-3.657	1.207
09	-2.694	-0.11	0.622	0.16
10	1.207	-4.147	-0.583	-2.479
11	0.488	-0.426	-0.289	-0.031
12	0.054	-0.233	0.393	-0.4
13	-0.117	-0.6	0.307	0.184

Standard thresholds

P-value	Threshold
0.001	4.38406
0.0005	5.505765
0.0001	7.52482