TBX1.H12CORE.0.S.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	TBX1.H12CORE.0.S.B
Gene (human)	TBX1 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Tbx1
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	15
Consensus	ndRGGTGKGARRddn
GC content	50.02%
Information content (bits; total / per base)	13.743 / 0.916
Data sources	HT-SELEX
Aligned words	5392

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 3 experiments	median	0.718	0.689	0.641	0.621	0.591	0.581
Non-Methyl HT-SELEX, 3 experiments	best	0.823	0.793	0.713	0.693	0.627	0.625

TF superclass	Immunoglobulin fold {6} (TFClass)
TF class	T-Box factors {6.5} (TFClass)
TF family	TBX1-related {6.5.3} (TFClass)
TF subfamily	{6.5.3.0} (TFClass)
TFClass ID	TFClass: 6.5.3.0.1
HGNC	HGNC:11592
MGI	MGI:98493
EntrezGene (human)	GeneID:6899 (SSTAR profile)
EntrezGene (mouse)	GeneID:21380 (SSTAR profile)
UniProt ID (human)	TBX1_HUMAN
UniProt ID (mouse)	TBX1_MOUSE
UniProt AC (human)	O43435 (TFClass)
UniProt AC (mouse)	P70323 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	3
Methyl-HT-SELEX	0

PCM	TBX1.H12CORE.0.S.B.pcm
PWM	TBX1.H12CORE.0.S.B.pwm
PFM	TBX1.H12CORE.0.S.B.pfm
Alignment	TBX1.H12CORE.0.S.B.words.tsv
Threshold to P-value map	TBX1.H12CORE.0.S.B.thr
Motif in other formats
JASPAR format	TBX1.H12CORE.0.S.B_jaspar_format.txt
MEME format	TBX1.H12CORE.0.S.B_meme_format.meme
Transfac format	TBX1.H12CORE.0.S.B_transfac_format.txt
Homer format	TBX1.H12CORE.0.S.B_homer_format_0.001.txt TBX1.H12CORE.0.S.B_homer_format_0.0005.txt TBX1.H12CORE.0.S.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1684.5	893.5	1469.5	1344.5
02	2086.75	571.75	1559.75	1173.75
03	3390.0	97.0	1738.0	167.0
04	219.0	64.0	5008.0	101.0
05	5.0	1.0	5385.0	1.0
06	74.0	136.0	8.0	5174.0
07	4.0	0.0	5388.0	0.0
08	40.0	134.0	1486.0	3732.0
09	11.0	4.0	5295.0	82.0
10	4387.0	712.0	129.0	164.0
11	3825.0	105.0	1017.0	445.0
12	2711.0	253.0	1983.0	445.0
13	1827.0	188.0	1926.0	1451.0
14	1506.0	511.0	1549.0	1826.0
15	1363.25	912.25	1932.25	1184.25

PFM

	A	C	G	T
01	0.312	0.166	0.273	0.249
02	0.387	0.106	0.289	0.218
03	0.629	0.018	0.322	0.031
04	0.041	0.012	0.929	0.019
05	0.001	0.0	0.999	0.0
06	0.014	0.025	0.001	0.96
07	0.001	0.0	0.999	0.0
08	0.007	0.025	0.276	0.692
09	0.002	0.001	0.982	0.015
10	0.814	0.132	0.024	0.03
11	0.709	0.019	0.189	0.083
12	0.503	0.047	0.368	0.083
13	0.339	0.035	0.357	0.269
14	0.279	0.095	0.287	0.339
15	0.253	0.169	0.358	0.22

PWM

	A	C	G	T
01	0.223	-0.41	0.086	-0.003
02	0.436	-0.856	0.146	-0.138
03	0.921	-2.611	0.254	-2.077
04	-1.809	-3.016	1.311	-2.572
05	-5.241	-6.061	1.384	-6.061
06	-2.875	-2.28	-4.891	1.344
07	-5.392	-6.443	1.384	-6.443
08	-3.467	-2.294	0.097	1.017
09	-4.632	-5.392	1.367	-2.775
10	1.179	-0.637	-2.332	-2.095
11	1.042	-2.534	-0.281	-1.105
12	0.698	-1.666	0.385	-1.105
13	0.304	-1.96	0.356	0.074
14	0.111	-0.967	0.139	0.303
15	0.011	-0.39	0.36	-0.129

Standard thresholds

P-value	Threshold
0.001	2.99491
0.0005	4.29231
0.0001	6.90921