TAL1.H12RSNP.2.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	TAL1.H12RSNP.2.P.B
Gene (human)	TAL1 (GeneCards)
Gene synonyms (human)	BHLHA17, SCL, TCL5
Gene (mouse)	Tal1
Gene synonyms (mouse)	Scl, Tal-1
LOGO
LOGO (reverse complement)
Motif subtype	2
Quality	B

Motif length	14
Consensus	nnvRvWRvCAGvWR
GC content	52.02%
Information content (bits; total / per base)	8.02 / 0.573
Data sources	ChIP-Seq
Aligned words	1003

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	27 (163)	0.652	0.773	0.469	0.652	0.648	0.757	1.568	2.41	15.229	61.143
Mouse	33 (190)	0.631	0.742	0.451	0.611	0.651	0.748	1.607	2.406	20.32	78.658

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	1.367	0.819	0.048	0.046

TF superclass	Basic domains {1} (TFClass)
TF class	Basic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF family	Tal-related {1.2.3} (TFClass)
TF subfamily	TAL-HEN {1.2.3.1} (TFClass)
TFClass ID	TFClass: 1.2.3.1.1
HGNC	HGNC:11556
MGI	MGI:98480
EntrezGene (human)	GeneID:6886 (SSTAR profile)
EntrezGene (mouse)	GeneID:21349 (SSTAR profile)
UniProt ID (human)	TAL1_HUMAN
UniProt ID (mouse)	TAL1_MOUSE
UniProt AC (human)	P17542 (TFClass)
UniProt AC (mouse)	P22091 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	27 human, 33 mouse
HT-SELEX	0
Methyl-HT-SELEX	0

PCM	TAL1.H12RSNP.2.P.B.pcm
PWM	TAL1.H12RSNP.2.P.B.pwm
PFM	TAL1.H12RSNP.2.P.B.pfm
Alignment	TAL1.H12RSNP.2.P.B.words.tsv
Threshold to P-value map	TAL1.H12RSNP.2.P.B.thr
Motif in other formats
JASPAR format	TAL1.H12RSNP.2.P.B_jaspar_format.txt
MEME format	TAL1.H12RSNP.2.P.B_meme_format.meme
Transfac format	TAL1.H12RSNP.2.P.B_transfac_format.txt
Homer format	TAL1.H12RSNP.2.P.B_homer_format_0.001.txt TAL1.H12RSNP.2.P.B_homer_format_0.0005.txt TAL1.H12RSNP.2.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	345.0	204.0	270.0	184.0
02	294.0	267.0	291.0	151.0
03	436.0	152.0	271.0	144.0
04	330.0	46.0	535.0	92.0
05	240.0	284.0	453.0	26.0
06	682.0	47.0	75.0	199.0
07	433.0	69.0	465.0	36.0
08	441.0	160.0	380.0	22.0
09	74.0	809.0	111.0	9.0
10	839.0	14.0	8.0	142.0
11	26.0	72.0	822.0	83.0
12	296.0	467.0	201.0	39.0
13	241.0	12.0	39.0	711.0
14	121.0	38.0	742.0	102.0

PFM

	A	C	G	T
01	0.344	0.203	0.269	0.183
02	0.293	0.266	0.29	0.151
03	0.435	0.152	0.27	0.144
04	0.329	0.046	0.533	0.092
05	0.239	0.283	0.452	0.026
06	0.68	0.047	0.075	0.198
07	0.432	0.069	0.464	0.036
08	0.44	0.16	0.379	0.022
09	0.074	0.807	0.111	0.009
10	0.836	0.014	0.008	0.142
11	0.026	0.072	0.82	0.083
12	0.295	0.466	0.2	0.039
13	0.24	0.012	0.039	0.709
14	0.121	0.038	0.74	0.102

PWM

	A	C	G	T
01	0.317	-0.205	0.073	-0.307
02	0.158	0.062	0.148	-0.503
03	0.55	-0.496	0.077	-0.55
04	0.273	-1.666	0.754	-0.991
05	-0.044	0.124	0.588	-2.209
06	0.996	-1.645	-1.191	-0.229
07	0.543	-1.272	0.614	-1.901
08	0.562	-0.445	0.413	-2.365
09	-1.204	1.167	-0.806	-3.158
10	1.203	-2.776	-3.256	-0.563
11	-2.209	-1.231	1.183	-1.092
12	0.165	0.619	-0.219	-1.824
13	-0.039	-2.912	-1.824	1.038
14	-0.721	-1.849	1.08	-0.89

Standard thresholds

P-value	Threshold
0.001	4.97171
0.0005	5.65811
0.0001	7.05396