TAL1.H12RSNP.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	TAL1.H12RSNP.0.P.B
Gene (human)	TAL1 (GeneCards)
Gene synonyms (human)	BHLHA17, SCL, TCL5
Gene (mouse)	Tal1
Gene synonyms (mouse)	Scl, Tal-1
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	19
Consensus	bYKbnnnnnnvWGATAAvv
GC content	46.19%
Information content (bits; total / per base)	12.169 / 0.64
Data sources	ChIP-Seq
Aligned words	1054

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	27 (163)	0.917	0.965	0.873	0.935	0.902	0.956	4.191	4.757	214.721	422.509
Mouse	33 (190)	0.897	0.96	0.842	0.923	0.9	0.956	4.036	4.963	203.997	369.149

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	5.135	12.475	0.249	0.197

TF superclass	Basic domains {1} (TFClass)
TF class	Basic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF family	Tal-related {1.2.3} (TFClass)
TF subfamily	TAL-HEN {1.2.3.1} (TFClass)
TFClass ID	TFClass: 1.2.3.1.1
HGNC	HGNC:11556
MGI	MGI:98480
EntrezGene (human)	GeneID:6886 (SSTAR profile)
EntrezGene (mouse)	GeneID:21349 (SSTAR profile)
UniProt ID (human)	TAL1_HUMAN
UniProt ID (mouse)	TAL1_MOUSE
UniProt AC (human)	P17542 (TFClass)
UniProt AC (mouse)	P22091 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	27 human, 33 mouse
HT-SELEX	0
Methyl-HT-SELEX	0

PCM	TAL1.H12RSNP.0.P.B.pcm
PWM	TAL1.H12RSNP.0.P.B.pwm
PFM	TAL1.H12RSNP.0.P.B.pfm
Alignment	TAL1.H12RSNP.0.P.B.words.tsv
Threshold to P-value map	TAL1.H12RSNP.0.P.B.thr
Motif in other formats
JASPAR format	TAL1.H12RSNP.0.P.B_jaspar_format.txt
MEME format	TAL1.H12RSNP.0.P.B_meme_format.meme
Transfac format	TAL1.H12RSNP.0.P.B_transfac_format.txt
Homer format	TAL1.H12RSNP.0.P.B_homer_format_0.001.txt TAL1.H12RSNP.0.P.B_homer_format_0.0005.txt TAL1.H12RSNP.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	96.0	596.0	209.0	153.0
02	48.0	146.0	132.0	728.0
03	10.0	46.0	788.0	210.0
04	84.0	263.0	435.0	272.0
05	238.0	252.0	296.0	268.0
06	258.0	235.0	316.0	245.0
07	263.0	235.0	351.0	205.0
08	268.0	247.0	311.0	228.0
09	242.0	257.0	309.0	246.0
10	371.0	172.0	298.0	213.0
11	168.0	437.0	315.0	134.0
12	670.0	19.0	13.0	352.0
13	2.0	0.0	1052.0	0.0
14	1049.0	0.0	3.0	2.0
15	11.0	7.0	18.0	1018.0
16	967.0	5.0	8.0	74.0
17	888.0	14.0	120.0	32.0
18	199.0	192.0	559.0	104.0
19	382.0	217.0	378.0	77.0

PFM

	A	C	G	T
01	0.091	0.565	0.198	0.145
02	0.046	0.139	0.125	0.691
03	0.009	0.044	0.748	0.199
04	0.08	0.25	0.413	0.258
05	0.226	0.239	0.281	0.254
06	0.245	0.223	0.3	0.232
07	0.25	0.223	0.333	0.194
08	0.254	0.234	0.295	0.216
09	0.23	0.244	0.293	0.233
10	0.352	0.163	0.283	0.202
11	0.159	0.415	0.299	0.127
12	0.636	0.018	0.012	0.334
13	0.002	0.0	0.998	0.0
14	0.995	0.0	0.003	0.002
15	0.01	0.007	0.017	0.966
16	0.917	0.005	0.008	0.07
17	0.843	0.013	0.114	0.03
18	0.189	0.182	0.53	0.099
19	0.362	0.206	0.359	0.073

PWM

	A	C	G	T
01	-0.998	0.813	-0.23	-0.539
02	-1.674	-0.585	-0.685	1.012
03	-3.118	-1.715	1.091	-0.225
04	-1.129	-0.002	0.499	0.032
05	-0.101	-0.044	0.116	0.017
06	-0.021	-0.114	0.181	-0.072
07	-0.002	-0.114	0.285	-0.249
08	0.017	-0.064	0.165	-0.144
09	-0.085	-0.025	0.158	-0.068
10	0.34	-0.423	0.122	-0.211
11	-0.446	0.503	0.177	-0.67
12	0.929	-2.549	-2.89	0.288
13	-4.262	-5.027	1.379	-5.027
14	1.377	-5.027	-4.025	-4.262
15	-3.036	-3.413	-2.598	1.347
16	1.295	-3.673	-3.304	-1.253
17	1.21	-2.824	-0.779	-2.062
18	-0.279	-0.314	0.749	-0.92
19	0.369	-0.193	0.359	-1.214

Standard thresholds

P-value	Threshold
0.001	4.04416
0.0005	5.12106
0.0001	7.28621