TAL1.H12CORE.2.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	TAL1.H12CORE.2.P.B
Gene (human)	TAL1 (GeneCards)
Gene synonyms (human)	BHLHA17, SCL, TCL5
Gene (mouse)	Tal1
Gene synonyms (mouse)	Scl, Tal-1
LOGO
LOGO (reverse complement)
Motif subtype	2
Quality	B

Motif length	14
Consensus	vnRvhRRCAGvTGb
GC content	51.83%
Information content (bits; total / per base)	9.878 / 0.706
Data sources	ChIP-Seq
Aligned words	1020

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	27 (163)	0.669	0.799	0.488	0.736	0.638	0.778	1.559	2.888	29.009	86.092
Mouse	33 (190)	0.632	0.775	0.462	0.675	0.635	0.758	1.589	2.742	25.493	96.854

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	1.336	0.738	0.026	0.052

TF superclass	Basic domains {1} (TFClass)
TF class	Basic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF family	Tal-related {1.2.3} (TFClass)
TF subfamily	TAL-HEN {1.2.3.1} (TFClass)
TFClass ID	TFClass: 1.2.3.1.1
HGNC	HGNC:11556
MGI	MGI:98480
EntrezGene (human)	GeneID:6886 (SSTAR profile)
EntrezGene (mouse)	GeneID:21349 (SSTAR profile)
UniProt ID (human)	TAL1_HUMAN
UniProt ID (mouse)	TAL1_MOUSE
UniProt AC (human)	P17542 (TFClass)
UniProt AC (mouse)	P22091 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	27 human, 33 mouse
HT-SELEX	0
Methyl-HT-SELEX	0

PCM	TAL1.H12CORE.2.P.B.pcm
PWM	TAL1.H12CORE.2.P.B.pwm
PFM	TAL1.H12CORE.2.P.B.pfm
Alignment	TAL1.H12CORE.2.P.B.words.tsv
Threshold to P-value map	TAL1.H12CORE.2.P.B.thr
Motif in other formats
JASPAR format	TAL1.H12CORE.2.P.B_jaspar_format.txt
MEME format	TAL1.H12CORE.2.P.B_meme_format.meme
Transfac format	TAL1.H12CORE.2.P.B_transfac_format.txt
Homer format	TAL1.H12CORE.2.P.B_homer_format_0.001.txt TAL1.H12CORE.2.P.B_homer_format_0.0005.txt TAL1.H12CORE.2.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	277.0	452.0	190.0	101.0
02	604.0	128.0	128.0	160.0
03	210.0	67.0	660.0	83.0
04	295.0	178.0	519.0	28.0
05	606.0	139.0	116.0	159.0
06	687.0	75.0	169.0	89.0
07	496.0	103.0	393.0	28.0
08	16.0	971.0	21.0	12.0
09	969.0	10.0	10.0	31.0
10	22.0	116.0	811.0	71.0
11	372.0	441.0	164.0	43.0
12	90.0	35.0	48.0	847.0
13	73.0	29.0	817.0	101.0
14	86.0	241.0	370.0	323.0

PFM

	A	C	G	T
01	0.272	0.443	0.186	0.099
02	0.592	0.125	0.125	0.157
03	0.206	0.066	0.647	0.081
04	0.289	0.175	0.509	0.027
05	0.594	0.136	0.114	0.156
06	0.674	0.074	0.166	0.087
07	0.486	0.101	0.385	0.027
08	0.016	0.952	0.021	0.012
09	0.95	0.01	0.01	0.03
10	0.022	0.114	0.795	0.07
11	0.365	0.432	0.161	0.042
12	0.088	0.034	0.047	0.83
13	0.072	0.028	0.801	0.099
14	0.084	0.236	0.363	0.317

PWM

	A	C	G	T
01	0.082	0.569	-0.292	-0.916
02	0.858	-0.683	-0.683	-0.462
03	-0.193	-1.318	0.947	-1.109
04	0.145	-0.357	0.707	-2.156
05	0.862	-0.601	-0.78	-0.468
06	0.987	-1.208	-0.408	-1.04
07	0.662	-0.897	0.43	-2.156
08	-2.673	1.332	-2.424	-2.928
09	1.33	-3.086	-3.086	-2.06
10	-2.381	-0.78	1.152	-1.261
11	0.376	0.545	-0.438	-1.747
12	-1.029	-1.944	-1.641	1.196
13	-1.234	-2.123	1.16	-0.916
14	-1.074	-0.056	0.37	0.235

Standard thresholds

P-value	Threshold
0.001	4.72521
0.0005	5.52801
0.0001	7.18246