TAL1.H12CORE.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	TAL1.H12CORE.0.P.B
Gene (human)	TAL1 (GeneCards)
Gene synonyms (human)	BHLHA17, SCL, TCL5
Gene (mouse)	Tal1
Gene synonyms (mouse)	Scl, Tal-1
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	19
Consensus	bbKbnnnnnvvWGATAASv
GC content	48.78%
Information content (bits; total / per base)	12.215 / 0.643
Data sources	ChIP-Seq
Aligned words	1001

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	27 (163)	0.92	0.974	0.876	0.951	0.9	0.96	4.094	4.694	237.0	428.161
Mouse	33 (190)	0.907	0.969	0.855	0.938	0.903	0.963	4.034	4.826	215.994	392.174

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	4.177	9.823	0.245	0.189

TF superclass	Basic domains {1} (TFClass)
TF class	Basic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF family	Tal-related {1.2.3} (TFClass)
TF subfamily	TAL-HEN {1.2.3.1} (TFClass)
TFClass ID	TFClass: 1.2.3.1.1
HGNC	HGNC:11556
MGI	MGI:98480
EntrezGene (human)	GeneID:6886 (SSTAR profile)
EntrezGene (mouse)	GeneID:21349 (SSTAR profile)
UniProt ID (human)	TAL1_HUMAN
UniProt ID (mouse)	TAL1_MOUSE
UniProt AC (human)	P17542 (TFClass)
UniProt AC (mouse)	P22091 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	27 human, 33 mouse
HT-SELEX	0
Methyl-HT-SELEX	0

PCM	TAL1.H12CORE.0.P.B.pcm
PWM	TAL1.H12CORE.0.P.B.pwm
PFM	TAL1.H12CORE.0.P.B.pfm
Alignment	TAL1.H12CORE.0.P.B.words.tsv
Threshold to P-value map	TAL1.H12CORE.0.P.B.thr
Motif in other formats
JASPAR format	TAL1.H12CORE.0.P.B_jaspar_format.txt
MEME format	TAL1.H12CORE.0.P.B_meme_format.meme
Transfac format	TAL1.H12CORE.0.P.B_transfac_format.txt
Homer format	TAL1.H12CORE.0.P.B_homer_format_0.001.txt TAL1.H12CORE.0.P.B_homer_format_0.0005.txt TAL1.H12CORE.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	87.0	499.0	241.0	174.0
02	65.0	207.0	154.0	575.0
03	31.0	57.0	632.0	281.0
04	84.0	218.0	505.0	194.0
05	179.0	253.0	309.0	260.0
06	213.0	234.0	297.0	257.0
07	208.0	259.0	357.0	177.0
08	209.0	277.0	312.0	203.0
09	210.0	281.0	278.0	232.0
10	335.0	172.0	347.0	147.0
11	153.0	426.0	322.0	100.0
12	663.0	13.0	17.0	308.0
13	2.0	0.0	999.0	0.0
14	991.0	4.0	2.0	4.0
15	2.0	15.0	6.0	978.0
16	942.0	5.0	8.0	46.0
17	852.0	16.0	117.0	16.0
18	121.0	229.0	593.0	58.0
19	342.0	227.0	390.0	42.0

PFM

	A	C	G	T
01	0.087	0.499	0.241	0.174
02	0.065	0.207	0.154	0.574
03	0.031	0.057	0.631	0.281
04	0.084	0.218	0.504	0.194
05	0.179	0.253	0.309	0.26
06	0.213	0.234	0.297	0.257
07	0.208	0.259	0.357	0.177
08	0.209	0.277	0.312	0.203
09	0.21	0.281	0.278	0.232
10	0.335	0.172	0.347	0.147
11	0.153	0.426	0.322	0.1
12	0.662	0.013	0.017	0.308
13	0.002	0.0	0.998	0.0
14	0.99	0.004	0.002	0.004
15	0.002	0.015	0.006	0.977
16	0.941	0.005	0.008	0.046
17	0.851	0.016	0.117	0.016
18	0.121	0.229	0.592	0.058
19	0.342	0.227	0.39	0.042

PWM

	A	C	G	T
01	-1.044	0.687	-0.037	-0.36
02	-1.329	-0.188	-0.481	0.828
03	-2.041	-1.456	0.922	0.115
04	-1.078	-0.137	0.699	-0.253
05	-0.332	0.011	0.21	0.038
06	-0.16	-0.067	0.17	0.026
07	-0.184	0.034	0.353	-0.343
08	-0.179	0.101	0.219	-0.208
09	-0.174	0.115	0.104	-0.075
10	0.29	-0.372	0.325	-0.527
11	-0.488	0.529	0.251	-0.907
12	0.97	-2.84	-2.599	0.206
13	-4.214	-4.983	1.379	-4.983
14	1.371	-3.784	-4.214	-3.784
15	-4.214	-2.712	-3.485	1.358
16	1.32	-3.623	-3.254	-1.664
17	1.22	-2.654	-0.753	-2.654
18	-0.719	-0.088	0.859	-1.44
19	0.311	-0.097	0.441	-1.751

Standard thresholds

P-value	Threshold
0.001	4.00561
0.0005	5.09096
0.0001	7.29436