SUH.H12RSNP.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	SUH.H12RSNP.0.P.B
Gene (human)	RBPJ (GeneCards)
Gene synonyms (human)	IGKJRB, IGKJRB1, RBPJK, RBPSUH
Gene (mouse)	Rbpj
Gene synonyms (mouse)	Igkjrb1, Igkrsbp, Rbpsuh
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	12
Consensus	bnSYSTGGGAAM
GC content	55.22%
Information content (bits; total / per base)	10.738 / 0.895
Data sources	ChIP-Seq
Aligned words	83

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	21 (128)	0.663	0.866	0.571	0.791	0.681	0.887	2.107	3.594	41.989	283.921
Mouse	11 (56)	0.695	0.867	0.599	0.786	0.727	0.881	2.306	3.821	57.748	276.409

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	2.923	2.315	0.133	0.067

TF superclass	Immunoglobulin fold {6} (TFClass)
TF class	Rel homology region (RHR) factors {6.1} (TFClass)
TF family	CSL-related {6.1.4} (TFClass)
TF subfamily	M {6.1.4.1} (TFClass)
TFClass ID	TFClass: 6.1.4.1.1
HGNC	HGNC:5724
MGI	MGI:96522
EntrezGene (human)	GeneID:3516 (SSTAR profile)
EntrezGene (mouse)	GeneID:19664 (SSTAR profile)
UniProt ID (human)	SUH_HUMAN
UniProt ID (mouse)	SUH_MOUSE
UniProt AC (human)	Q06330 (TFClass)
UniProt AC (mouse)	P31266 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	21 human, 11 mouse
HT-SELEX	0
Methyl-HT-SELEX	0

PCM	SUH.H12RSNP.0.P.B.pcm
PWM	SUH.H12RSNP.0.P.B.pwm
PFM	SUH.H12RSNP.0.P.B.pfm
Alignment	SUH.H12RSNP.0.P.B.words.tsv
Threshold to P-value map	SUH.H12RSNP.0.P.B.thr
Motif in other formats
JASPAR format	SUH.H12RSNP.0.P.B_jaspar_format.txt
MEME format	SUH.H12RSNP.0.P.B_meme_format.meme
Transfac format	SUH.H12RSNP.0.P.B_transfac_format.txt
Homer format	SUH.H12RSNP.0.P.B_homer_format_0.001.txt SUH.H12RSNP.0.P.B_homer_format_0.0005.txt SUH.H12RSNP.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	9.0	21.0	37.0	16.0
02	27.0	10.0	27.0	19.0
03	2.0	37.0	32.0	12.0
04	10.0	46.0	2.0	25.0
05	5.0	23.0	50.0	5.0
06	7.0	0.0	0.0	76.0
07	6.0	1.0	76.0	0.0
08	18.0	1.0	62.0	2.0
09	0.0	1.0	81.0	1.0
10	72.0	2.0	2.0	7.0
11	70.0	1.0	12.0	0.0
12	39.0	26.0	0.0	18.0

PFM

	A	C	G	T
01	0.108	0.253	0.446	0.193
02	0.325	0.12	0.325	0.229
03	0.024	0.446	0.386	0.145
04	0.12	0.554	0.024	0.301
05	0.06	0.277	0.602	0.06
06	0.084	0.0	0.0	0.916
07	0.072	0.012	0.916	0.0
08	0.217	0.012	0.747	0.024
09	0.0	0.012	0.976	0.012
10	0.867	0.024	0.024	0.084
11	0.843	0.012	0.145	0.0
12	0.47	0.313	0.0	0.217

PWM

	A	C	G	T
01	-0.771	0.011	0.556	-0.245
02	0.252	-0.677	0.252	-0.083
03	-1.951	0.556	0.415	-0.511
04	-0.677	0.768	-1.951	0.178
05	-1.275	0.098	0.849	-1.275
06	-0.992	-2.985	-2.985	1.261
07	-1.124	-2.34	1.261	-2.985
08	-0.134	-2.34	1.06	-1.951
09	-2.985	-2.34	1.324	-2.34
10	1.207	-1.951	-1.951	-0.992
11	1.18	-2.34	-0.511	-2.985
12	0.607	0.215	-2.985	-0.134

Standard thresholds

P-value	Threshold
0.001	4.81227
0.0005	5.61976
0.0001	7.271615