STF1.H12INVITRO.0.PSM.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	STF1.H12INVITRO.0.PSM.A
Gene (human)	NR5A1 (GeneCards)
Gene synonyms (human)	AD4BP, FTZF1, SF1
Gene (mouse)	Nr5a1
Gene synonyms (mouse)	Ftzf1
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	12
Consensus	nbCAAGGYCRnn
GC content	52.24%
Information content (bits; total / per base)	12.436 / 1.036
Data sources	ChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words	9896

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	4 (10)	0.684	0.827	0.621	0.808	0.613	0.793	2.142	3.677	10.0	90.041
Mouse	1 (7)	0.847	0.862	0.774	0.795	0.875	0.885	3.568	3.63	49.337	86.18

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.994	0.989	0.99	0.983	0.979	0.969
Overall, 2 experiments	best	0.994	0.99	0.99	0.984	0.981	0.972
Methyl HT-SELEX, 1 experiments	median	0.994	0.989	0.989	0.983	0.976	0.966
Methyl HT-SELEX, 1 experiments	best	0.994	0.989	0.989	0.983	0.976	0.966
Non-Methyl HT-SELEX, 1 experiments	median	0.994	0.99	0.99	0.984	0.981	0.972
Non-Methyl HT-SELEX, 1 experiments	best	0.994	0.99	0.99	0.984	0.981	0.972

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	Nuclear receptors with C4 zinc fingers {2.1} (TFClass)
TF family	FTZF1-related (NR5A) {2.1.5} (TFClass)
TF subfamily	{2.1.5.0} (TFClass)
TFClass ID	TFClass: 2.1.5.0.1
HGNC	HGNC:7983
MGI	MGI:1346833
EntrezGene (human)	GeneID:2516 (SSTAR profile)
EntrezGene (mouse)	GeneID:26423 (SSTAR profile)
UniProt ID (human)	STF1_HUMAN
UniProt ID (mouse)	STF1_MOUSE
UniProt AC (human)	Q13285 (TFClass)
UniProt AC (mouse)	P33242 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	4 human, 1 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	STF1.H12INVITRO.0.PSM.A.pcm
PWM	STF1.H12INVITRO.0.PSM.A.pwm
PFM	STF1.H12INVITRO.0.PSM.A.pfm
Alignment	STF1.H12INVITRO.0.PSM.A.words.tsv
Threshold to P-value map	STF1.H12INVITRO.0.PSM.A.thr
Motif in other formats
JASPAR format	STF1.H12INVITRO.0.PSM.A_jaspar_format.txt
MEME format	STF1.H12INVITRO.0.PSM.A_meme_format.meme
Transfac format	STF1.H12INVITRO.0.PSM.A_transfac_format.txt
Homer format	STF1.H12INVITRO.0.PSM.A_homer_format_0.001.txt STF1.H12INVITRO.0.PSM.A_homer_format_0.0005.txt STF1.H12INVITRO.0.PSM.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2064.5	1976.5	3539.5	2315.5
02	1215.5	2138.5	1383.5	5158.5
03	34.0	8936.0	786.0	140.0
04	9698.0	1.0	194.0	3.0
05	9895.0	0.0	0.0	1.0
06	0.0	0.0	9896.0	0.0
07	0.0	0.0	9896.0	0.0
08	886.0	1765.0	195.0	7050.0
09	179.0	8397.0	247.0	1073.0
10	6596.0	351.0	2317.0	632.0
11	2569.5	2759.5	1318.5	3248.5
12	1868.75	2275.75	3658.75	2092.75

PFM

	A	C	G	T
01	0.209	0.2	0.358	0.234
02	0.123	0.216	0.14	0.521
03	0.003	0.903	0.079	0.014
04	0.98	0.0	0.02	0.0
05	1.0	0.0	0.0	0.0
06	0.0	0.0	1.0	0.0
07	0.0	0.0	1.0	0.0
08	0.09	0.178	0.02	0.712
09	0.018	0.849	0.025	0.108
10	0.667	0.035	0.234	0.064
11	0.26	0.279	0.133	0.328
12	0.189	0.23	0.37	0.211

PWM

	A	C	G	T
01	-0.181	-0.224	0.358	-0.066
02	-0.71	-0.146	-0.58	0.734
03	-4.223	1.284	-1.145	-2.857
04	1.365	-6.621	-2.535	-6.147
05	1.385	-6.982	-6.982	-6.621
06	-6.982	-6.982	1.386	-6.982
07	-6.982	-6.982	1.386	-6.982
08	-1.025	-0.337	-2.53	1.047
09	-2.614	1.221	-2.296	-0.834
10	0.98	-1.947	-0.066	-1.362
11	0.038	0.109	-0.629	0.272
12	-0.28	-0.083	0.391	-0.167

Standard thresholds

P-value	Threshold
0.001	3.47287
0.0005	4.90282
0.0001	7.39922