STF1.H12CORE.0.PSM.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	STF1.H12CORE.0.PSM.A
Gene (human)	NR5A1 (GeneCards)
Gene synonyms (human)	AD4BP, FTZF1, SF1
Gene (mouse)	Nr5a1
Gene synonyms (mouse)	Ftzf1
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	12
Consensus	nbbYCAAGGYCR
GC content	54.39%
Information content (bits; total / per base)	12.734 / 1.061
Data sources	ChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words	997

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	4 (10)	0.732	0.829	0.653	0.817	0.662	0.803	2.419	3.848	12.854	90.658
Mouse	1 (7)	0.845	0.86	0.736	0.762	0.879	0.9	3.961	4.134	53.77	95.854

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.991	0.985	0.984	0.975	0.96	0.947
Overall, 2 experiments	best	0.992	0.986	0.984	0.975	0.962	0.949
Methyl HT-SELEX, 1 experiments	median	0.991	0.985	0.984	0.975	0.962	0.949
Methyl HT-SELEX, 1 experiments	best	0.991	0.985	0.984	0.975	0.962	0.949
Non-Methyl HT-SELEX, 1 experiments	median	0.992	0.986	0.984	0.975	0.958	0.944
Non-Methyl HT-SELEX, 1 experiments	best	0.992	0.986	0.984	0.975	0.958	0.944

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	Nuclear receptors with C4 zinc fingers {2.1} (TFClass)
TF family	FTZF1-related (NR5A) {2.1.5} (TFClass)
TF subfamily	{2.1.5.0} (TFClass)
TFClass ID	TFClass: 2.1.5.0.1
HGNC	HGNC:7983
MGI	MGI:1346833
EntrezGene (human)	GeneID:2516 (SSTAR profile)
EntrezGene (mouse)	GeneID:26423 (SSTAR profile)
UniProt ID (human)	STF1_HUMAN
UniProt ID (mouse)	STF1_MOUSE
UniProt AC (human)	Q13285 (TFClass)
UniProt AC (mouse)	P33242 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	4 human, 1 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	STF1.H12CORE.0.PSM.A.pcm
PWM	STF1.H12CORE.0.PSM.A.pwm
PFM	STF1.H12CORE.0.PSM.A.pfm
Alignment	STF1.H12CORE.0.PSM.A.words.tsv
Threshold to P-value map	STF1.H12CORE.0.PSM.A.thr
Motif in other formats
JASPAR format	STF1.H12CORE.0.PSM.A_jaspar_format.txt
MEME format	STF1.H12CORE.0.PSM.A_meme_format.meme
Transfac format	STF1.H12CORE.0.PSM.A_transfac_format.txt
Homer format	STF1.H12CORE.0.PSM.A_homer_format_0.001.txt STF1.H12CORE.0.PSM.A_homer_format_0.0005.txt STF1.H12CORE.0.PSM.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	388.0	156.0	213.0	240.0
02	141.0	189.0	477.0	190.0
03	58.0	335.0	224.0	380.0
04	30.0	375.0	22.0	570.0
05	5.0	943.0	43.0	6.0
06	952.0	30.0	11.0	4.0
07	945.0	6.0	36.0	10.0
08	10.0	3.0	980.0	4.0
09	6.0	11.0	978.0	2.0
10	95.0	395.0	22.0	485.0
11	11.0	898.0	12.0	76.0
12	770.0	30.0	118.0	79.0

PFM

	A	C	G	T
01	0.389	0.156	0.214	0.241
02	0.141	0.19	0.478	0.191
03	0.058	0.336	0.225	0.381
04	0.03	0.376	0.022	0.572
05	0.005	0.946	0.043	0.006
06	0.955	0.03	0.011	0.004
07	0.948	0.006	0.036	0.01
08	0.01	0.003	0.983	0.004
09	0.006	0.011	0.981	0.002
10	0.095	0.396	0.022	0.486
11	0.011	0.901	0.012	0.076
12	0.772	0.03	0.118	0.079

PWM

	A	C	G	T
01	0.44	-0.464	-0.156	-0.038
02	-0.564	-0.275	0.646	-0.269
03	-1.436	0.294	-0.106	0.419
04	-2.068	0.406	-2.359	0.823
05	-3.619	1.326	-1.725	-3.481
06	1.335	-2.068	-2.982	-3.78
07	1.328	-3.481	-1.895	-3.064
08	-3.064	-3.972	1.364	-3.78
09	-3.481	-2.982	1.362	-4.21
10	-0.953	0.458	-2.359	0.662
11	-2.982	1.277	-2.906	-1.172
12	1.123	-2.068	-0.74	-1.134

Standard thresholds

P-value	Threshold
0.001	3.76056
0.0005	4.86945
0.0001	7.111195