STAT3.H12RSNP.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	STAT3.H12RSNP.0.P.B
Gene (human)	STAT3 (GeneCards)
Gene synonyms (human)	APRF
Gene (mouse)	Stat3
Gene synonyms (mouse)	Aprf
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	11
Consensus	hTTCCCRKMAv
GC content	45.92%
Information content (bits; total / per base)	10.989 / 0.999
Data sources	ChIP-Seq
Aligned words	1003

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	29 (182)	0.839	0.947	0.755	0.914	0.839	0.938	3.022	4.102	175.563	436.284
Mouse	48 (289)	0.841	0.94	0.727	0.89	0.84	0.943	2.746	4.076	176.367	422.658

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	17.203	6.603	0.263	0.2

TF superclass	Immunoglobulin fold {6} (TFClass)
TF class	STAT domain factors {6.2} (TFClass)
TF family	STAT {6.2.1} (TFClass)
TF subfamily	{6.2.1.0} (TFClass)
TFClass ID	TFClass: 6.2.1.0.3
HGNC	HGNC:11364
MGI	MGI:103038
EntrezGene (human)	GeneID:6774 (SSTAR profile)
EntrezGene (mouse)	GeneID:20848 (SSTAR profile)
UniProt ID (human)	STAT3_HUMAN
UniProt ID (mouse)	STAT3_MOUSE
UniProt AC (human)	P40763 (TFClass)
UniProt AC (mouse)	P42227 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	29 human, 48 mouse
HT-SELEX	0
Methyl-HT-SELEX	0

PCM	STAT3.H12RSNP.0.P.B.pcm
PWM	STAT3.H12RSNP.0.P.B.pwm
PFM	STAT3.H12RSNP.0.P.B.pfm
Alignment	STAT3.H12RSNP.0.P.B.words.tsv
Threshold to P-value map	STAT3.H12RSNP.0.P.B.thr
Motif in other formats
JASPAR format	STAT3.H12RSNP.0.P.B_jaspar_format.txt
MEME format	STAT3.H12RSNP.0.P.B_meme_format.meme
Transfac format	STAT3.H12RSNP.0.P.B_transfac_format.txt
Homer format	STAT3.H12RSNP.0.P.B_homer_format_0.001.txt STAT3.H12RSNP.0.P.B_homer_format_0.0005.txt STAT3.H12RSNP.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	161.0	335.0	134.0	373.0
02	7.0	13.0	8.0	975.0
03	14.0	8.0	55.0	926.0
04	141.0	818.0	10.0	34.0
05	11.0	779.0	6.0	207.0
06	0.0	629.0	0.0	374.0
07	276.0	27.0	679.0	21.0
08	33.0	34.0	745.0	191.0
09	733.0	232.0	5.0	33.0
10	901.0	39.0	36.0	27.0
11	409.0	158.0	316.0	120.0

PFM

	A	C	G	T
01	0.161	0.334	0.134	0.372
02	0.007	0.013	0.008	0.972
03	0.014	0.008	0.055	0.923
04	0.141	0.816	0.01	0.034
05	0.011	0.777	0.006	0.206
06	0.0	0.627	0.0	0.373
07	0.275	0.027	0.677	0.021
08	0.033	0.034	0.743	0.19
09	0.731	0.231	0.005	0.033
10	0.898	0.039	0.036	0.027
11	0.408	0.158	0.315	0.12

PWM

	A	C	G	T
01	-0.439	0.288	-0.621	0.395
02	-3.365	-2.842	-3.256	1.353
03	-2.776	-3.256	-1.493	1.301
04	-0.57	1.178	-3.069	-1.955
05	-2.988	1.129	-3.487	-0.19
06	-4.985	0.916	-4.985	0.398
07	0.095	-2.173	0.992	-2.408
08	-1.984	-1.955	1.084	-0.27
09	1.068	-0.077	-3.625	-1.984
10	1.274	-1.824	-1.901	-2.173
11	0.487	-0.458	0.23	-0.73

Standard thresholds

P-value	Threshold
0.001	4.48252
0.0005	5.422045
0.0001	7.287085