STAT3.H12INVITRO.0.P.D motif - HOmo sapiens COmprehensive MOdel COllection

Motif	STAT3.H12INVITRO.0.P.D
Gene (human)	STAT3 (GeneCards)
Gene synonyms (human)	APRF
Gene (mouse)	Stat3
Gene synonyms (mouse)	Aprf
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	D

Motif length	13
Consensus	bvbTTCCYRKMAv
GC content	48.32%
Information content (bits; total / per base)	11.444 / 0.88
Data sources	ChIP-Seq
Aligned words	1000

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	29 (182)	0.854	0.952	0.779	0.907	0.845	0.939	3.191	4.317	177.663	459.62
Mouse	48 (289)	0.852	0.948	0.743	0.902	0.85	0.948	2.891	4.343	179.481	433.921

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	10.509	5.377	0.248	0.201

TF superclass	Immunoglobulin fold {6} (TFClass)
TF class	STAT domain factors {6.2} (TFClass)
TF family	STAT {6.2.1} (TFClass)
TF subfamily	{6.2.1.0} (TFClass)
TFClass ID	TFClass: 6.2.1.0.3
HGNC	HGNC:11364
MGI	MGI:103038
EntrezGene (human)	GeneID:6774 (SSTAR profile)
EntrezGene (mouse)	GeneID:20848 (SSTAR profile)
UniProt ID (human)	STAT3_HUMAN
UniProt ID (mouse)	STAT3_MOUSE
UniProt AC (human)	P40763 (TFClass)
UniProt AC (mouse)	P42227 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	29 human, 48 mouse
HT-SELEX	0
Methyl-HT-SELEX	0

PCM	STAT3.H12INVITRO.0.P.D.pcm
PWM	STAT3.H12INVITRO.0.P.D.pwm
PFM	STAT3.H12INVITRO.0.P.D.pfm
Alignment	STAT3.H12INVITRO.0.P.D.words.tsv
Threshold to P-value map	STAT3.H12INVITRO.0.P.D.thr
Motif in other formats
JASPAR format	STAT3.H12INVITRO.0.P.D_jaspar_format.txt
MEME format	STAT3.H12INVITRO.0.P.D_meme_format.meme
Transfac format	STAT3.H12INVITRO.0.P.D_transfac_format.txt
Homer format	STAT3.H12INVITRO.0.P.D_homer_format_0.001.txt STAT3.H12INVITRO.0.P.D_homer_format_0.0005.txt STAT3.H12INVITRO.0.P.D_homer_format_0.0001.txt

PCM

	A	C	G	T
01	103.0	456.0	257.0	184.0
02	390.0	221.0	241.0	148.0
03	117.0	313.0	157.0	413.0
04	7.0	8.0	6.0	979.0
05	13.0	5.0	31.0	951.0
06	140.0	818.0	8.0	34.0
07	2.0	820.0	6.0	172.0
08	12.0	592.0	0.0	396.0
09	236.0	23.0	722.0	19.0
10	50.0	30.0	709.0	211.0
11	719.0	250.0	6.0	25.0
12	887.0	47.0	33.0	33.0
13	356.0	176.0	346.0	122.0

PFM

	A	C	G	T
01	0.103	0.456	0.257	0.184
02	0.39	0.221	0.241	0.148
03	0.117	0.313	0.157	0.413
04	0.007	0.008	0.006	0.979
05	0.013	0.005	0.031	0.951
06	0.14	0.818	0.008	0.034
07	0.002	0.82	0.006	0.172
08	0.012	0.592	0.0	0.396
09	0.236	0.023	0.722	0.019
10	0.05	0.03	0.709	0.211
11	0.719	0.25	0.006	0.025
12	0.887	0.047	0.033	0.033
13	0.356	0.176	0.346	0.122

PWM

	A	C	G	T
01	-0.877	0.598	0.027	-0.304
02	0.442	-0.122	-0.036	-0.52
03	-0.752	0.223	-0.461	0.499
04	-3.362	-3.253	-3.484	1.36
05	-2.839	-3.622	-2.04	1.331
06	-0.574	1.181	-3.253	-1.952
07	-4.213	1.183	-3.484	-0.371
08	-2.909	0.858	-4.982	0.457
09	-0.057	-2.32	1.056	-2.497
10	-1.582	-2.071	1.038	-0.168
11	1.052	0.0	-3.484	-2.243
12	1.261	-1.642	-1.981	-1.981
13	0.351	-0.348	0.323	-0.71

Standard thresholds

P-value	Threshold
0.001	4.33951
0.0005	5.31131
0.0001	7.281275