STAT1.H12RSNP.1.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	STAT1.H12RSNP.1.P.B
Gene (human)	STAT1 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Stat1
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	18
Consensus	hhbnRSTTTCdnTTYCYb
GC content	40.11%
Information content (bits; total / per base)	13.548 / 0.753
Data sources	ChIP-Seq
Aligned words	1001

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	10 (65)	0.476	0.957	0.341	0.936	0.584	0.975	1.515	6.672	0.066	292.538
Mouse	38 (214)	0.707	0.892	0.612	0.852	0.781	0.936	3.137	5.399	46.24	181.699

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	1.173	0.393	0.023	0.007

TF superclass	Immunoglobulin fold {6} (TFClass)
TF class	STAT domain factors {6.2} (TFClass)
TF family	STAT {6.2.1} (TFClass)
TF subfamily	{6.2.1.0} (TFClass)
TFClass ID	TFClass: 6.2.1.0.1
HGNC	HGNC:11362
MGI	MGI:103063
EntrezGene (human)	GeneID:6772 (SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)	STAT1_HUMAN
UniProt ID (mouse)	STAT1_MOUSE
UniProt AC (human)	P42224 (TFClass)
UniProt AC (mouse)	P42225 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	10 human, 38 mouse
HT-SELEX	0
Methyl-HT-SELEX	0

PCM	STAT1.H12RSNP.1.P.B.pcm
PWM	STAT1.H12RSNP.1.P.B.pwm
PFM	STAT1.H12RSNP.1.P.B.pfm
Alignment	STAT1.H12RSNP.1.P.B.words.tsv
Threshold to P-value map	STAT1.H12RSNP.1.P.B.thr
Motif in other formats
JASPAR format	STAT1.H12RSNP.1.P.B_jaspar_format.txt
MEME format	STAT1.H12RSNP.1.P.B_meme_format.meme
Transfac format	STAT1.H12RSNP.1.P.B_transfac_format.txt
Homer format	STAT1.H12RSNP.1.P.B_homer_format_0.001.txt STAT1.H12RSNP.1.P.B_homer_format_0.0005.txt STAT1.H12RSNP.1.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	163.0	275.0	162.0	401.0
02	151.0	235.0	145.0	470.0
03	125.0	141.0	134.0	601.0
04	231.0	385.0	160.0	225.0
05	652.0	37.0	224.0	88.0
06	26.0	267.0	673.0	35.0
07	20.0	56.0	13.0	912.0
08	21.0	45.0	20.0	915.0
09	21.0	66.0	42.0	872.0
10	10.0	890.0	16.0	85.0
11	391.0	145.0	257.0	208.0
12	173.0	198.0	269.0	361.0
13	21.0	59.0	24.0	897.0
14	7.0	21.0	21.0	952.0
15	12.0	320.0	20.0	649.0
16	38.0	771.0	15.0	177.0
17	74.0	568.0	47.0	312.0
18	100.0	383.0	123.0	395.0

PFM

	A	C	G	T
01	0.163	0.275	0.162	0.401
02	0.151	0.235	0.145	0.47
03	0.125	0.141	0.134	0.6
04	0.231	0.385	0.16	0.225
05	0.651	0.037	0.224	0.088
06	0.026	0.267	0.672	0.035
07	0.02	0.056	0.013	0.911
08	0.021	0.045	0.02	0.914
09	0.021	0.066	0.042	0.871
10	0.01	0.889	0.016	0.085
11	0.391	0.145	0.257	0.208
12	0.173	0.198	0.269	0.361
13	0.021	0.059	0.024	0.896
14	0.007	0.021	0.021	0.951
15	0.012	0.32	0.02	0.648
16	0.038	0.77	0.015	0.177
17	0.074	0.567	0.047	0.312
18	0.1	0.383	0.123	0.395

PWM

	A	C	G	T
01	-0.425	0.094	-0.431	0.469
02	-0.501	-0.062	-0.541	0.627
03	-0.687	-0.568	-0.619	0.872
04	-0.079	0.428	-0.443	-0.106
05	0.953	-1.873	-0.11	-1.033
06	-2.207	0.064	0.985	-1.926
07	-2.451	-1.474	-2.84	1.288
08	-2.406	-1.685	-2.451	1.291
09	-2.406	-1.314	-1.751	1.243
10	-3.067	1.264	-2.654	-1.067
11	0.444	-0.541	0.026	-0.184
12	-0.366	-0.232	0.072	0.364
13	-2.406	-1.423	-2.282	1.272
14	-3.363	-2.406	-2.406	1.331
15	-2.91	0.244	-2.451	0.949
16	-1.847	1.121	-2.712	-0.343
17	-1.202	0.816	-1.643	0.219
18	-0.907	0.423	-0.703	0.454

Standard thresholds

P-value	Threshold
0.001	3.73121
0.0005	4.74401
0.0001	6.87441