STAT1.H12RSNP.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	STAT1.H12RSNP.0.P.B
Gene (human)	STAT1 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Stat1
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	18
Consensus	nnnnnbbnYTTCCYRKAA
GC content	45.84%
Information content (bits; total / per base)	11.792 / 0.655
Data sources	ChIP-Seq
Aligned words	1017

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	10 (65)	0.878	0.974	0.813	0.954	0.87	0.967	3.623	5.701	182.77	498.745
Mouse	38 (214)	0.819	0.932	0.729	0.852	0.813	0.924	2.904	3.853	105.325	355.276

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	1.492	1.478	0.064	0.029

TF superclass	Immunoglobulin fold {6} (TFClass)
TF class	STAT domain factors {6.2} (TFClass)
TF family	STAT {6.2.1} (TFClass)
TF subfamily	{6.2.1.0} (TFClass)
TFClass ID	TFClass: 6.2.1.0.1
HGNC	HGNC:11362
MGI	MGI:103063
EntrezGene (human)	GeneID:6772 (SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)	STAT1_HUMAN
UniProt ID (mouse)	STAT1_MOUSE
UniProt AC (human)	P42224 (TFClass)
UniProt AC (mouse)	P42225 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	10 human, 38 mouse
HT-SELEX	0
Methyl-HT-SELEX	0

PCM	STAT1.H12RSNP.0.P.B.pcm
PWM	STAT1.H12RSNP.0.P.B.pwm
PFM	STAT1.H12RSNP.0.P.B.pfm
Alignment	STAT1.H12RSNP.0.P.B.words.tsv
Threshold to P-value map	STAT1.H12RSNP.0.P.B.thr
Motif in other formats
JASPAR format	STAT1.H12RSNP.0.P.B_jaspar_format.txt
MEME format	STAT1.H12RSNP.0.P.B_meme_format.meme
Transfac format	STAT1.H12RSNP.0.P.B_transfac_format.txt
Homer format	STAT1.H12RSNP.0.P.B_homer_format_0.001.txt STAT1.H12RSNP.0.P.B_homer_format_0.0005.txt STAT1.H12RSNP.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	244.0	327.0	163.0	283.0
02	239.0	379.0	192.0	207.0
03	260.0	280.0	160.0	317.0
04	243.0	270.0	222.0	282.0
05	202.0	322.0	233.0	260.0
06	142.0	360.0	187.0	328.0
07	124.0	452.0	259.0	182.0
08	377.0	264.0	195.0	181.0
09	103.0	308.0	44.0	562.0
10	11.0	15.0	5.0	986.0
11	6.0	3.0	27.0	981.0
12	73.0	920.0	5.0	19.0
13	13.0	876.0	3.0	125.0
14	148.0	421.0	18.0	430.0
15	379.0	36.0	530.0	72.0
16	53.0	31.0	707.0	226.0
17	861.0	127.0	11.0	18.0
18	946.0	12.0	28.0	31.0

PFM

	A	C	G	T
01	0.24	0.322	0.16	0.278
02	0.235	0.373	0.189	0.204
03	0.256	0.275	0.157	0.312
04	0.239	0.265	0.218	0.277
05	0.199	0.317	0.229	0.256
06	0.14	0.354	0.184	0.323
07	0.122	0.444	0.255	0.179
08	0.371	0.26	0.192	0.178
09	0.101	0.303	0.043	0.553
10	0.011	0.015	0.005	0.97
11	0.006	0.003	0.027	0.965
12	0.072	0.905	0.005	0.019
13	0.013	0.861	0.003	0.123
14	0.146	0.414	0.018	0.423
15	0.373	0.035	0.521	0.071
16	0.052	0.03	0.695	0.222
17	0.847	0.125	0.011	0.018
18	0.93	0.012	0.028	0.03

PWM

	A	C	G	T
01	-0.041	0.25	-0.441	0.106
02	-0.061	0.397	-0.279	-0.204
03	0.022	0.096	-0.459	0.219
04	-0.045	0.06	-0.135	0.103
05	-0.228	0.235	-0.087	0.022
06	-0.577	0.346	-0.305	0.253
07	-0.711	0.572	0.018	-0.332
08	0.392	0.037	-0.263	-0.337
09	-0.894	0.191	-1.722	0.789
10	-3.001	-2.728	-3.638	1.35
11	-3.5	-3.991	-2.187	1.345
12	-1.231	1.281	-3.638	-2.513
13	-2.855	1.232	-3.991	-0.703
14	-0.536	0.502	-2.563	0.523
15	0.397	-1.915	0.731	-1.245
16	-1.543	-2.057	1.018	-0.117
17	1.215	-0.687	-3.001	-2.563
18	1.309	-2.925	-2.153	-2.057

Standard thresholds

P-value	Threshold
0.001	4.21246
0.0005	5.19821
0.0001	7.21821