STAT1.H12INVIVO.1.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	STAT1.H12INVIVO.1.P.B
Gene (human)	STAT1 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Stat1
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	18
Consensus	hWhRGTTTCdnTTTCYnn
GC content	38.71%
Information content (bits; total / per base)	16.911 / 0.94
Data sources	ChIP-Seq
Aligned words	305

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	10 (65)	0.478	0.967	0.35	0.953	0.564	0.977	1.445	6.842	0.004	305.886
Mouse	38 (214)	0.717	0.902	0.629	0.866	0.776	0.937	3.088	5.343	49.153	202.398

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	0.824	0.464	0.002	-0.015

TF superclass	Immunoglobulin fold {6} (TFClass)
TF class	STAT domain factors {6.2} (TFClass)
TF family	STAT {6.2.1} (TFClass)
TF subfamily	{6.2.1.0} (TFClass)
TFClass ID	TFClass: 6.2.1.0.1
HGNC	HGNC:11362
MGI	MGI:103063
EntrezGene (human)	GeneID:6772 (SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)	STAT1_HUMAN
UniProt ID (mouse)	STAT1_MOUSE
UniProt AC (human)	P42224 (TFClass)
UniProt AC (mouse)	P42225 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	10 human, 38 mouse
HT-SELEX	0
Methyl-HT-SELEX	0

PCM	STAT1.H12INVIVO.1.P.B.pcm
PWM	STAT1.H12INVIVO.1.P.B.pwm
PFM	STAT1.H12INVIVO.1.P.B.pfm
Alignment	STAT1.H12INVIVO.1.P.B.words.tsv
Threshold to P-value map	STAT1.H12INVIVO.1.P.B.thr
Motif in other formats
JASPAR format	STAT1.H12INVIVO.1.P.B_jaspar_format.txt
MEME format	STAT1.H12INVIVO.1.P.B_meme_format.meme
Transfac format	STAT1.H12INVIVO.1.P.B_transfac_format.txt
Homer format	STAT1.H12INVIVO.1.P.B_homer_format_0.001.txt STAT1.H12INVIVO.1.P.B_homer_format_0.0005.txt STAT1.H12INVIVO.1.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	48.0	64.0	37.0	156.0
02	36.0	32.0	31.0	206.0
03	76.0	117.0	45.0	67.0
04	222.0	4.0	64.0	15.0
05	4.0	70.0	227.0	4.0
06	2.0	3.0	2.0	298.0
07	1.0	2.0	2.0	300.0
08	2.0	8.0	4.0	291.0
09	0.0	296.0	1.0	8.0
10	127.0	32.0	103.0	43.0
11	64.0	61.0	62.0	118.0
12	2.0	7.0	3.0	293.0
13	0.0	1.0	0.0	304.0
14	2.0	93.0	0.0	210.0
15	5.0	234.0	5.0	61.0
16	11.0	190.0	23.0	81.0
17	31.0	130.0	31.0	113.0
18	79.0	84.0	57.0	85.0

PFM

	A	C	G	T
01	0.157	0.21	0.121	0.511
02	0.118	0.105	0.102	0.675
03	0.249	0.384	0.148	0.22
04	0.728	0.013	0.21	0.049
05	0.013	0.23	0.744	0.013
06	0.007	0.01	0.007	0.977
07	0.003	0.007	0.007	0.984
08	0.007	0.026	0.013	0.954
09	0.0	0.97	0.003	0.026
10	0.416	0.105	0.338	0.141
11	0.21	0.2	0.203	0.387
12	0.007	0.023	0.01	0.961
13	0.0	0.003	0.0	0.997
14	0.007	0.305	0.0	0.689
15	0.016	0.767	0.016	0.2
16	0.036	0.623	0.075	0.266
17	0.102	0.426	0.102	0.37
18	0.259	0.275	0.187	0.279

PWM

	A	C	G	T
01	-0.452	-0.172	-0.704	0.706
02	-0.73	-0.843	-0.874	0.982
03	-0.003	0.422	-0.515	-0.127
04	1.056	-2.661	-0.172	-1.553
05	-2.661	-0.084	1.079	-2.661
06	-3.12	-2.864	-3.12	1.349
07	-3.465	-3.12	-3.12	1.356
08	-3.12	-2.109	-2.661	1.326
09	-3.995	1.343	-3.465	-2.109
10	0.503	-0.843	0.296	-0.559
11	-0.172	-0.219	-0.203	0.43
12	-3.12	-2.221	-2.864	1.332
13	-3.995	-3.465	-3.995	1.369
14	-3.12	0.195	-3.995	1.001
15	-2.492	1.109	-2.492	-0.219
16	-1.832	0.902	-1.157	0.059
17	-0.874	0.526	-0.874	0.387
18	0.035	0.095	-0.285	0.107

Standard thresholds

P-value	Threshold
0.001	2.20536
0.0005	3.46401
0.0001	6.12201