STAT1.H12INVITRO.1.P.D motif - HOmo sapiens COmprehensive MOdel COllection

Motif	STAT1.H12INVITRO.1.P.D
Gene (human)	STAT1 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Stat1
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	D

Motif length	18
Consensus	hhKhRGTTTCddTTTCYh
GC content	38.45%
Information content (bits; total / per base)	17.123 / 0.951
Data sources	ChIP-Seq
Aligned words	304

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	10 (65)	0.478	0.962	0.346	0.943	0.573	0.977	1.484	6.893	0	298.638
Mouse	38 (214)	0.716	0.897	0.624	0.862	0.779	0.939	3.159	5.465	49.473	191.495

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	0.877	0.288	0.019	-0.003

TF superclass	Immunoglobulin fold {6} (TFClass)
TF class	STAT domain factors {6.2} (TFClass)
TF family	STAT {6.2.1} (TFClass)
TF subfamily	{6.2.1.0} (TFClass)
TFClass ID	TFClass: 6.2.1.0.1
HGNC	HGNC:11362
MGI	MGI:103063
EntrezGene (human)	GeneID:6772 (SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)	STAT1_HUMAN
UniProt ID (mouse)	STAT1_MOUSE
UniProt AC (human)	P42224 (TFClass)
UniProt AC (mouse)	P42225 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	10 human, 38 mouse
HT-SELEX	0
Methyl-HT-SELEX	0

PCM	STAT1.H12INVITRO.1.P.D.pcm
PWM	STAT1.H12INVITRO.1.P.D.pwm
PFM	STAT1.H12INVITRO.1.P.D.pfm
Alignment	STAT1.H12INVITRO.1.P.D.words.tsv
Threshold to P-value map	STAT1.H12INVITRO.1.P.D.thr
Motif in other formats
JASPAR format	STAT1.H12INVITRO.1.P.D_jaspar_format.txt
MEME format	STAT1.H12INVITRO.1.P.D_meme_format.meme
Transfac format	STAT1.H12INVITRO.1.P.D_transfac_format.txt
Homer format	STAT1.H12INVITRO.1.P.D_homer_format_0.001.txt STAT1.H12INVITRO.1.P.D_homer_format_0.0005.txt STAT1.H12INVITRO.1.P.D_homer_format_0.0001.txt

PCM

	A	C	G	T
01	55.0	78.0	39.0	132.0
02	44.0	64.0	37.0	159.0
03	32.0	32.0	33.0	207.0
04	73.0	126.0	43.0	62.0
05	218.0	3.0	64.0	19.0
06	3.0	73.0	224.0	4.0
07	1.0	4.0	1.0	298.0
08	0.0	2.0	1.0	301.0
09	2.0	12.0	4.0	286.0
10	0.0	287.0	1.0	16.0
11	115.0	39.0	107.0	43.0
12	65.0	55.0	57.0	127.0
13	1.0	7.0	3.0	293.0
14	0.0	0.0	1.0	303.0
15	1.0	92.0	0.0	211.0
16	4.0	239.0	5.0	56.0
17	11.0	194.0	16.0	83.0
18	33.0	131.0	30.0	110.0

PFM

	A	C	G	T
01	0.181	0.257	0.128	0.434
02	0.145	0.211	0.122	0.523
03	0.105	0.105	0.109	0.681
04	0.24	0.414	0.141	0.204
05	0.717	0.01	0.211	0.063
06	0.01	0.24	0.737	0.013
07	0.003	0.013	0.003	0.98
08	0.0	0.007	0.003	0.99
09	0.007	0.039	0.013	0.941
10	0.0	0.944	0.003	0.053
11	0.378	0.128	0.352	0.141
12	0.214	0.181	0.188	0.418
13	0.003	0.023	0.01	0.964
14	0.0	0.0	0.003	0.997
15	0.003	0.303	0.0	0.694
16	0.013	0.786	0.016	0.184
17	0.036	0.638	0.053	0.273
18	0.109	0.431	0.099	0.362

PWM

	A	C	G	T
01	-0.316	0.026	-0.65	0.544
02	-0.533	-0.168	-0.701	0.728
03	-0.84	-0.84	-0.81	0.99
04	-0.04	0.498	-0.555	-0.199
05	1.042	-2.861	-0.168	-1.332
06	-2.861	-0.04	1.069	-2.658
07	-3.462	-2.658	-3.462	1.353
08	-3.992	-3.117	-3.462	1.362
09	-3.117	-1.752	-2.658	1.312
10	-3.992	1.315	-3.462	-1.491
11	0.408	-0.65	0.337	-0.555
12	-0.153	-0.316	-0.282	0.506
13	-3.462	-2.218	-2.861	1.336
14	-3.992	-3.992	-3.462	1.369
15	-3.462	0.188	-3.992	1.009
16	-2.658	1.133	-2.489	-0.299
17	-1.829	0.926	-1.491	0.087
18	-0.81	0.537	-0.902	0.364

Standard thresholds

P-value	Threshold
0.001	2.09986
0.0005	3.37726
0.0001	6.06506