STAT1.H12INVITRO.0.P.D motif - HOmo sapiens COmprehensive MOdel COllection

Motif	STAT1.H12INVITRO.0.P.D
Gene (human)	STAT1 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Stat1
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	D

Motif length	20
Consensus	vhbbYbhYTTCCYdKMAvhn
GC content	44.18%
Information content (bits; total / per base)	12.245 / 0.612
Data sources	ChIP-Seq
Aligned words	986

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	10 (65)	0.855	0.959	0.769	0.92	0.853	0.952	3.194	4.456	179.886	474.041
Mouse	38 (214)	0.853	0.934	0.763	0.872	0.867	0.941	3.401	4.643	124.28	389.553

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	1.145	0.287	0.025	0.018

TF superclass	Immunoglobulin fold {6} (TFClass)
TF class	STAT domain factors {6.2} (TFClass)
TF family	STAT {6.2.1} (TFClass)
TF subfamily	{6.2.1.0} (TFClass)
TFClass ID	TFClass: 6.2.1.0.1
HGNC	HGNC:11362
MGI	MGI:103063
EntrezGene (human)	GeneID:6772 (SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)	STAT1_HUMAN
UniProt ID (mouse)	STAT1_MOUSE
UniProt AC (human)	P42224 (TFClass)
UniProt AC (mouse)	P42225 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	10 human, 38 mouse
HT-SELEX	0
Methyl-HT-SELEX	0

PCM	STAT1.H12INVITRO.0.P.D.pcm
PWM	STAT1.H12INVITRO.0.P.D.pwm
PFM	STAT1.H12INVITRO.0.P.D.pfm
Alignment	STAT1.H12INVITRO.0.P.D.words.tsv
Threshold to P-value map	STAT1.H12INVITRO.0.P.D.thr
Motif in other formats
JASPAR format	STAT1.H12INVITRO.0.P.D_jaspar_format.txt
MEME format	STAT1.H12INVITRO.0.P.D_meme_format.meme
Transfac format	STAT1.H12INVITRO.0.P.D_transfac_format.txt
Homer format	STAT1.H12INVITRO.0.P.D_homer_format_0.001.txt STAT1.H12INVITRO.0.P.D_homer_format_0.0005.txt STAT1.H12INVITRO.0.P.D_homer_format_0.0001.txt

PCM

	A	C	G	T
01	168.0	309.0	367.0	142.0
02	215.0	169.0	150.0	452.0
03	81.0	211.0	208.0	486.0
04	56.0	304.0	148.0	478.0
05	44.0	462.0	93.0	387.0
06	110.0	449.0	241.0	186.0
07	430.0	171.0	164.0	221.0
08	102.0	190.0	95.0	599.0
09	3.0	3.0	2.0	978.0
10	3.0	8.0	4.0	971.0
11	26.0	900.0	3.0	57.0
12	11.0	720.0	3.0	252.0
13	65.0	424.0	63.0	434.0
14	345.0	72.0	427.0	142.0
15	78.0	32.0	560.0	316.0
16	717.0	180.0	34.0	55.0
17	885.0	46.0	23.0	32.0
18	477.0	146.0	230.0	133.0
19	136.0	336.0	129.0	385.0
20	166.0	353.0	283.0	184.0

PFM

	A	C	G	T
01	0.17	0.313	0.372	0.144
02	0.218	0.171	0.152	0.458
03	0.082	0.214	0.211	0.493
04	0.057	0.308	0.15	0.485
05	0.045	0.469	0.094	0.392
06	0.112	0.455	0.244	0.189
07	0.436	0.173	0.166	0.224
08	0.103	0.193	0.096	0.608
09	0.003	0.003	0.002	0.992
10	0.003	0.008	0.004	0.985
11	0.026	0.913	0.003	0.058
12	0.011	0.73	0.003	0.256
13	0.066	0.43	0.064	0.44
14	0.35	0.073	0.433	0.144
15	0.079	0.032	0.568	0.32
16	0.727	0.183	0.034	0.056
17	0.898	0.047	0.023	0.032
18	0.484	0.148	0.233	0.135
19	0.138	0.341	0.131	0.39
20	0.168	0.358	0.287	0.187

PWM

	A	C	G	T
01	-0.38	0.225	0.396	-0.546
02	-0.136	-0.374	-0.492	0.603
03	-1.099	-0.154	-0.169	0.675
04	-1.459	0.208	-0.506	0.659
05	-1.692	0.625	-0.963	0.449
06	-0.798	0.597	-0.022	-0.279
07	0.553	-0.363	-0.404	-0.108
08	-0.873	-0.258	-0.942	0.884
09	-3.962	-3.962	-4.2	1.373
10	-3.962	-3.24	-3.77	1.366
11	-2.192	1.29	-3.962	-1.441
12	-2.971	1.067	-3.962	0.022
13	-1.314	0.539	-1.344	0.563
14	0.334	-1.214	0.546	-0.546
15	-1.136	-1.996	0.817	0.247
16	1.063	-0.312	-1.939	-1.476
17	1.273	-1.649	-2.307	-1.996
18	0.657	-0.519	-0.069	-0.611
19	-0.589	0.308	-0.641	0.443
20	-0.392	0.357	0.137	-0.29

Standard thresholds

P-value	Threshold
0.001	4.13626
0.0005	5.13391
0.0001	7.16356