SRY.H12INVITRO.1.S.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	SRY.H12INVITRO.1.S.B
Gene (human)	SRY (GeneCards)
Gene synonyms (human)	TDF
Gene (mouse)	Sry
Gene synonyms (mouse)	Tdf, Tdy
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	17
Consensus	hMMWWTMhCATTGTYhn
GC content	32.92%
Information content (bits; total / per base)	17.015 / 1.001
Data sources	HT-SELEX
Aligned words	427

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 2 experiments	median	0.769	0.755	0.663	0.655	0.598	0.599
Non-Methyl HT-SELEX, 2 experiments	best	0.811	0.804	0.684	0.682	0.607	0.614

TF superclass	Other all-alpha-helical DNA-binding domains {4} (TFClass)
TF class	High-mobility group (HMG) domain factors {4.1} (TFClass)
TF family	SOX-related {4.1.1} (TFClass)
TF subfamily	Group A {4.1.1.1} (TFClass)
TFClass ID	TFClass: 4.1.1.1.1
HGNC	HGNC:11311
MGI	MGI:98660
EntrezGene (human)	GeneID:6736 (SSTAR profile)
EntrezGene (mouse)	GeneID:21674 (SSTAR profile)
UniProt ID (human)	SRY_HUMAN
UniProt ID (mouse)	SRY_MOUSE
UniProt AC (human)	Q05066 (TFClass)
UniProt AC (mouse)	Q05738 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	2
Methyl-HT-SELEX	0

PCM	SRY.H12INVITRO.1.S.B.pcm
PWM	SRY.H12INVITRO.1.S.B.pwm
PFM	SRY.H12INVITRO.1.S.B.pfm
Alignment	SRY.H12INVITRO.1.S.B.words.tsv
Threshold to P-value map	SRY.H12INVITRO.1.S.B.thr
Motif in other formats
JASPAR format	SRY.H12INVITRO.1.S.B_jaspar_format.txt
MEME format	SRY.H12INVITRO.1.S.B_meme_format.meme
Transfac format	SRY.H12INVITRO.1.S.B_transfac_format.txt
Homer format	SRY.H12INVITRO.1.S.B_homer_format_0.001.txt SRY.H12INVITRO.1.S.B_homer_format_0.0005.txt SRY.H12INVITRO.1.S.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	240.25	98.25	38.25	50.25
02	291.75	71.75	20.75	42.75
03	53.0	317.0	20.0	37.0
04	316.0	42.0	18.0	51.0
05	272.0	34.0	30.0	91.0
06	19.0	25.0	27.0	356.0
07	289.0	54.0	39.0	45.0
08	138.0	106.0	25.0	158.0
09	5.0	416.0	0.0	6.0
10	426.0	1.0	0.0	0.0
11	1.0	0.0	0.0	426.0
12	0.0	0.0	0.0	427.0
13	2.0	29.0	396.0	0.0
14	6.0	15.0	14.0	392.0
15	15.0	45.0	42.0	325.0
16	65.5	201.5	29.5	130.5
17	80.5	123.5	111.5	111.5

PFM

	A	C	G	T
01	0.563	0.23	0.09	0.118
02	0.683	0.168	0.049	0.1
03	0.124	0.742	0.047	0.087
04	0.74	0.098	0.042	0.119
05	0.637	0.08	0.07	0.213
06	0.044	0.059	0.063	0.834
07	0.677	0.126	0.091	0.105
08	0.323	0.248	0.059	0.37
09	0.012	0.974	0.0	0.014
10	0.998	0.002	0.0	0.0
11	0.002	0.0	0.0	0.998
12	0.0	0.0	0.0	1.0
13	0.005	0.068	0.927	0.0
14	0.014	0.035	0.033	0.918
15	0.035	0.105	0.098	0.761
16	0.153	0.472	0.069	0.306
17	0.189	0.289	0.261	0.261

PWM

	A	C	G	T
01	0.803	-0.082	-1.002	-0.738
02	0.996	-0.391	-1.582	-0.894
03	-0.686	1.079	-1.616	-1.034
04	1.076	-0.911	-1.713	-0.723
05	0.927	-1.115	-1.234	-0.157
06	-1.663	-1.407	-1.334	1.195
07	0.987	-0.668	-0.983	-0.845
08	0.254	-0.007	-1.407	0.388
09	-2.811	1.35	-4.27	-2.668
10	1.373	-3.763	-4.27	-4.27
11	-3.763	-4.27	-4.27	1.373
12	-4.27	-4.27	-4.27	1.376
13	-3.428	-1.266	1.301	-4.27
14	-2.668	-1.88	-1.943	1.291
15	-1.88	-0.845	-0.911	1.104
16	-0.48	0.629	-1.25	0.198
17	-0.278	0.144	0.043	0.043

Standard thresholds

P-value	Threshold
0.001	2.17861
0.0005	3.45471
0.0001	6.11441