MotifSRBP1.H12INVITRO.1.S.C
Gene (human)SREBF1
(GeneCards)
Gene synonyms (human)BHLHD1, SREBP1
Gene (mouse)Srebf1
Gene synonyms (mouse)Srebp1
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
C
Motif length12
ConsensusbdWSRCGTGAbv
GC content58.12%
Information content (bits; total / per base)11.18 / 0.932
Data sourcesHT-SELEX
Aligned words1327

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 3 (20) 0.838 0.895 0.76 0.841 0.83 0.896 3.169 4.689 103.858 433.796
Mouse 2 (14) 0.727 0.752 0.587 0.627 0.634 0.655 1.55 1.886 96.879 141.959

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.783 0.757 0.686 0.667 0.625 0.614
best 0.835 0.772 0.761 0.712 0.687 0.656
Methyl HT-SELEX, 1 experiments median 0.835 0.772 0.761 0.712 0.687 0.656
best 0.835 0.772 0.761 0.712 0.687 0.656
Non-Methyl HT-SELEX, 3 experiments median 0.758 0.757 0.641 0.646 0.581 0.59
best 0.807 0.757 0.73 0.688 0.668 0.639
TF superclassBasic domains {1} (TFClass)
TF classBasic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF familybHLH-ZIP {1.2.6} (TFClass)
TF subfamilySREBF {1.2.6.3} (TFClass)
TFClass IDTFClass: 1.2.6.3.1
HGNCHGNC:11289
MGIMGI:107606
EntrezGene (human)GeneID:6720
(SSTAR profile)
EntrezGene (mouse)GeneID:20787
(SSTAR profile)
UniProt ID (human)SRBP1_HUMAN
UniProt ID (mouse)SRBP1_MOUSE
UniProt AC (human)P36956
(TFClass)
UniProt AC (mouse)Q9WTN3
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 3 human, 2 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
01197.0299.0515.0316.0
02456.75174.75477.75217.75
03299.023.0255.0750.0
04200.0832.0205.090.0
05566.00.0753.08.0
060.01233.094.00.0
070.00.01327.00.0
080.00.00.01327.0
0918.00.01277.032.0
101101.011.0199.016.0
1181.0307.0344.0595.0
12246.5310.5617.5152.5
PFM
ACGT
010.1480.2250.3880.238
020.3440.1320.360.164
030.2250.0170.1920.565
040.1510.6270.1540.068
050.4270.00.5670.006
060.00.9290.0710.0
070.00.01.00.0
080.00.00.01.0
090.0140.00.9620.024
100.830.0080.150.012
110.0610.2310.2590.448
120.1860.2340.4650.115
PWM
ACGT
01-0.517-0.1030.438-0.048
020.318-0.6360.363-0.418
03-0.103-2.599-0.2610.813
04-0.5030.916-0.478-1.29
050.532-5.2230.817-3.528
06-5.2231.309-1.248-5.223
07-5.223-5.2231.382-5.223
08-5.223-5.223-5.2231.382
09-2.824-5.2231.344-2.289
101.196-3.261-0.507-2.931
11-1.393-0.0770.0360.582
12-0.295-0.0660.619-0.771
Standard thresholds
P-value Threshold
0.001 4.34316
0.0005 5.54052
0.0001 7.599915