MotifSRBP1.H12CORE.0.P.B
Gene (human)SREBF1
(GeneCards)
Gene synonyms (human)BHLHD1, SREBP1
Gene (mouse)Srebf1
Gene synonyms (mouse)Srebp1
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length12
ConsensusRTCASGTGAYbb
GC content53.47%
Information content (bits; total / per base)12.222 / 1.019
Data sourcesChIP-Seq
Aligned words1000

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 3 (20) 0.866 0.935 0.807 0.897 0.861 0.936 4.185 5.495 107.016 489.959
Mouse 2 (14) 0.785 0.882 0.702 0.778 0.702 0.822 2.243 2.615 155.444 276.328

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.774 0.75 0.66 0.652 0.595 0.597
best 0.919 0.892 0.829 0.799 0.733 0.715
Methyl HT-SELEX, 1 experiments median 0.919 0.892 0.829 0.799 0.733 0.715
best 0.919 0.892 0.829 0.799 0.733 0.715
Non-Methyl HT-SELEX, 3 experiments median 0.77 0.728 0.626 0.645 0.561 0.583
best 0.777 0.773 0.694 0.659 0.628 0.611
TF superclassBasic domains {1} (TFClass)
TF classBasic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF familybHLH-ZIP {1.2.6} (TFClass)
TF subfamilySREBF {1.2.6.3} (TFClass)
TFClass IDTFClass: 1.2.6.3.1
HGNCHGNC:11289
MGIMGI:107606
EntrezGene (human)GeneID:6720
(SSTAR profile)
EntrezGene (mouse)GeneID:20787
(SSTAR profile)
UniProt ID (human)SRBP1_HUMAN
UniProt ID (mouse)SRBP1_MOUSE
UniProt AC (human)P36956
(TFClass)
UniProt AC (mouse)Q9WTN3
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 3 human, 2 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
01421.0151.0425.03.0
0238.030.029.0903.0
0315.0718.0263.04.0
04729.00.0244.027.0
0517.0339.0599.045.0
0619.044.0932.05.0
0731.016.06.0947.0
081.016.0982.01.0
09937.017.022.024.0
109.0324.0109.0558.0
11111.0449.0190.0250.0
12128.0369.0143.0360.0
PFM
ACGT
010.4210.1510.4250.003
020.0380.030.0290.903
030.0150.7180.2630.004
040.7290.00.2440.027
050.0170.3390.5990.045
060.0190.0440.9320.005
070.0310.0160.0060.947
080.0010.0160.9820.001
090.9370.0170.0220.024
100.0090.3240.1090.558
110.1110.4490.190.25
120.1280.3690.1430.36
PWM
ACGT
010.518-0.50.528-3.975
02-1.846-2.071-2.1031.279
03-2.7111.0510.05-3.783
041.066-4.982-0.024-2.171
05-2.5980.3030.87-1.684
06-2.497-1.7061.311-3.622
07-2.04-2.653-3.4841.327
08-4.525-2.6531.363-4.525
091.316-2.598-2.362-2.281
10-3.1560.258-0.8210.799
11-0.8030.583-0.2720.0
12-0.6630.387-0.5530.363
Standard thresholds
P-value Threshold
0.001 3.984825
0.0005 5.105915
0.0001 7.10493