MotifSPIB.H12INVITRO.1.S.C
Gene (human)SPIB
(GeneCards)
Gene synonyms (human)
Gene (mouse)Spib
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
C
Motif length13
ConsensusRAAAGMGGAAGTd
GC content39.82%
Information content (bits; total / per base)18.914 / 1.455
Data sourcesHT-SELEX
Aligned words8799

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 4 (26) 0.949 0.958 0.91 0.925 0.94 0.949 4.802 5.091 494.088 646.796
Mouse 1 (5) 0.883 0.891 0.836 0.841 0.883 0.895 4.199 4.264 389.377 401.456

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 7 experiments median 0.991 0.985 0.973 0.96 0.868 0.86
best 1.0 0.999 0.999 0.999 0.993 0.992
Methyl HT-SELEX, 3 experiments median 0.991 0.985 0.973 0.96 0.919 0.904
best 1.0 0.999 0.999 0.999 0.993 0.992
Non-Methyl HT-SELEX, 4 experiments median 0.993 0.989 0.97 0.962 0.828 0.84
best 1.0 0.999 0.999 0.998 0.991 0.989

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.952 0.779 0.932 0.595
batch 2 0.751 0.49 0.8 0.62
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classTryptophan cluster factors {3.5} (TFClass)
TF familyEts-related {3.5.2} (TFClass)
TF subfamilySPI-like {3.5.2.5} (TFClass)
TFClass IDTFClass: 3.5.2.5.2
HGNCHGNC:11242
MGIMGI:892986
EntrezGene (human)GeneID:6689
(SSTAR profile)
EntrezGene (mouse)GeneID:272382
(SSTAR profile)
UniProt ID (human)SPIB_HUMAN
UniProt ID (mouse)SPIB_MOUSE
UniProt AC (human)Q01892
(TFClass)
UniProt AC (mouse)O35906
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 4 human, 1 mouse
HT-SELEX 4
Methyl-HT-SELEX 3
PCM
ACGT
016443.25466.251117.25772.25
027796.25167.25277.25558.25
038013.038.079.0669.0
046478.050.049.02222.0
05235.0210.08349.05.0
063196.05510.093.00.0
073.00.08796.00.0
080.00.08799.00.0
098799.00.00.00.0
108799.00.00.00.0
116.0413.08379.01.0
12128.0165.056.08450.0
133821.5753.51782.52441.5
PFM
ACGT
010.7320.0530.1270.088
020.8860.0190.0320.063
030.9110.0040.0090.076
040.7360.0060.0060.253
050.0270.0240.9490.001
060.3630.6260.0110.0
070.00.01.00.0
080.00.01.00.0
091.00.00.00.0
101.00.00.00.0
110.0010.0470.9520.0
120.0150.0190.0060.96
130.4340.0860.2030.277
PWM
ACGT
011.074-1.548-0.676-1.045
021.265-2.564-2.064-1.368
031.292-4.002-3.299-1.188
041.079-3.741-3.760.01
05-2.228-2.3391.333-5.713
060.3730.918-3.14-6.877
07-6.035-6.8771.385-6.877
08-6.877-6.8771.386-6.877
091.386-6.877-6.877-6.877
101.386-6.877-6.877-6.877
11-5.584-1.6681.337-6.512
12-2.828-2.578-3.6321.345
130.552-1.069-0.210.104
Standard thresholds
P-value Threshold
0.001 -2.23183
0.0005 -0.26409
0.0001 3.78753