MotifSPIB.H12CORE.2.SM.B
Gene (human)SPIB
(GeneCards)
Gene synonyms (human)
Gene (mouse)Spib
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype2
Quality
B
Motif length16
ConsensusvvdAAWGAGGAAGTdn
GC content44.17%
Information content (bits; total / per base)19.408 / 1.213
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words8860

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 4 (26) 0.929 0.941 0.904 0.912 0.945 0.952 5.185 5.389 510.414 635.481
Mouse 1 (5) 0.848 0.863 0.816 0.826 0.88 0.894 4.392 4.457 380.699 415.032

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 7 experiments median 0.991 0.985 0.96 0.957 0.843 0.835
best 1.0 1.0 0.999 0.999 0.991 0.99
Methyl HT-SELEX, 3 experiments median 0.991 0.985 0.978 0.968 0.908 0.899
best 1.0 1.0 0.999 0.999 0.991 0.99
Non-Methyl HT-SELEX, 4 experiments median 0.99 0.984 0.955 0.945 0.802 0.817
best 0.999 0.998 0.997 0.996 0.983 0.979

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.945 0.764 0.925 0.603
batch 2 0.757 0.473 0.794 0.608
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classTryptophan cluster factors {3.5} (TFClass)
TF familyEts-related {3.5.2} (TFClass)
TF subfamilySPI-like {3.5.2.5} (TFClass)
TFClass IDTFClass: 3.5.2.5.2
HGNCHGNC:11242
MGIMGI:892986
EntrezGene (human)GeneID:6689
(SSTAR profile)
EntrezGene (mouse)GeneID:272382
(SSTAR profile)
UniProt ID (human)SPIB_HUMAN
UniProt ID (mouse)SPIB_MOUSE
UniProt AC (human)Q01892
(TFClass)
UniProt AC (mouse)O35906
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 4 human, 1 mouse
HT-SELEX 4
Methyl-HT-SELEX 3
PCM
ACGT
011860.52176.53504.51318.5
021818.01717.04241.01084.0
033706.0483.03851.0820.0
047201.089.0640.0930.0
057799.013.066.0982.0
063689.041.0108.05022.0
07171.0150.08488.051.0
087468.080.01305.07.0
090.00.08858.02.0
100.01.08859.00.0
118860.00.00.00.0
128858.01.00.01.0
130.025.08835.00.0
147.022.011.08820.0
153656.0233.03342.01629.0
161953.02440.03038.01429.0
PFM
ACGT
010.210.2460.3960.149
020.2050.1940.4790.122
030.4180.0550.4350.093
040.8130.010.0720.105
050.880.0010.0070.111
060.4160.0050.0120.567
070.0190.0170.9580.006
080.8430.0090.1470.001
090.00.01.00.0
100.00.01.00.0
111.00.00.00.0
121.00.00.00.0
130.00.0030.9970.0
140.0010.0020.0010.995
150.4130.0260.3770.184
160.220.2750.3430.161
PWM
ACGT
01-0.174-0.0180.458-0.518
02-0.197-0.2540.649-0.714
030.514-1.5190.553-0.992
041.178-3.19-1.239-0.866
051.258-4.978-3.481-0.812
060.51-3.937-3.0010.818
07-2.549-2.6781.343-3.729
081.215-3.294-0.528-5.477
09-6.883-6.8831.385-6.252
10-6.883-6.5191.385-6.883
111.386-6.883-6.883-6.883
121.385-6.519-6.883-6.519
13-6.883-4.3981.383-6.883
14-5.477-4.515-5.1181.381
150.501-2.2430.411-0.307
16-0.1260.0970.316-0.438
Standard thresholds
P-value Threshold
0.001 -3.44629
0.0005 -1.39874
0.0001 2.88066