SPIB.H12CORE.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	SPIB.H12CORE.0.P.B
Gene (human)	SPIB (GeneCards)
Gene synonyms (human)
Gene (mouse)	Spib
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	16
Consensus	RRWGRGGAAGTGRvdn
GC content	46.04%
Information content (bits; total / per base)	17.184 / 1.074
Data sources	ChIP-Seq
Aligned words	1003

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	4 (26)	0.987	0.991	0.972	0.98	0.989	0.993	6.542	6.932	656.09	896.921
Mouse	1 (5)	0.931	0.947	0.918	0.931	0.947	0.958	5.852	5.937	540.013	626.538

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 7 experiments	median	0.981	0.97	0.923	0.897	0.815	0.802
Overall, 7 experiments	best	0.998	0.998	0.992	0.989	0.967	0.96
Methyl HT-SELEX, 3 experiments	median	0.982	0.97	0.962	0.944	0.911	0.89
Methyl HT-SELEX, 3 experiments	best	0.998	0.998	0.992	0.989	0.967	0.96
Non-Methyl HT-SELEX, 4 experiments	median	0.969	0.953	0.909	0.888	0.771	0.774
Non-Methyl HT-SELEX, 4 experiments	best	0.994	0.99	0.984	0.977	0.958	0.945

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.885	0.467	0.86	0.573
batch 2	0.729	0.385	0.667	0.519

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Tryptophan cluster factors {3.5} (TFClass)
TF family	Ets-related {3.5.2} (TFClass)
TF subfamily	SPI-like {3.5.2.5} (TFClass)
TFClass ID	TFClass: 3.5.2.5.2
HGNC	HGNC:11242
MGI	MGI:892986
EntrezGene (human)	GeneID:6689 (SSTAR profile)
EntrezGene (mouse)	GeneID:272382 (SSTAR profile)
UniProt ID (human)	SPIB_HUMAN
UniProt ID (mouse)	SPIB_MOUSE
UniProt AC (human)	Q01892 (TFClass)
UniProt AC (mouse)	O35906 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	4 human, 1 mouse
HT-SELEX	4
Methyl-HT-SELEX	3

PCM	SPIB.H12CORE.0.P.B.pcm
PWM	SPIB.H12CORE.0.P.B.pwm
PFM	SPIB.H12CORE.0.P.B.pfm
Alignment	SPIB.H12CORE.0.P.B.words.tsv
Threshold to P-value map	SPIB.H12CORE.0.P.B.thr
Motif in other formats
JASPAR format	SPIB.H12CORE.0.P.B_jaspar_format.txt
MEME format	SPIB.H12CORE.0.P.B_meme_format.meme
Transfac format	SPIB.H12CORE.0.P.B_transfac_format.txt
Homer format	SPIB.H12CORE.0.P.B_homer_format_0.001.txt SPIB.H12CORE.0.P.B_homer_format_0.0005.txt SPIB.H12CORE.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	745.0	36.0	120.0	102.0
02	700.0	34.0	184.0	85.0
03	679.0	14.0	94.0	216.0
04	136.0	47.0	808.0	12.0
05	654.0	68.0	277.0	4.0
06	68.0	0.0	935.0	0.0
07	1.0	0.0	1002.0	0.0
08	1002.0	1.0	0.0	0.0
09	996.0	1.0	2.0	4.0
10	33.0	190.0	779.0	1.0
11	15.0	8.0	8.0	972.0
12	5.0	36.0	960.0	2.0
13	566.0	116.0	279.0	42.0
14	412.0	145.0	318.0	128.0
15	537.0	131.0	178.0	157.0
16	217.0	307.0	310.0	169.0

PFM

	A	C	G	T
01	0.743	0.036	0.12	0.102
02	0.698	0.034	0.183	0.085
03	0.677	0.014	0.094	0.215
04	0.136	0.047	0.806	0.012
05	0.652	0.068	0.276	0.004
06	0.068	0.0	0.932	0.0
07	0.001	0.0	0.999	0.0
08	0.999	0.001	0.0	0.0
09	0.993	0.001	0.002	0.004
10	0.033	0.189	0.777	0.001
11	0.015	0.008	0.008	0.969
12	0.005	0.036	0.957	0.002
13	0.564	0.116	0.278	0.042
14	0.411	0.145	0.317	0.128
15	0.535	0.131	0.177	0.157
16	0.216	0.306	0.309	0.168

PWM

	A	C	G	T
01	1.084	-1.901	-0.73	-0.89
02	1.022	-1.955	-0.307	-1.069
03	0.992	-2.776	-0.97	-0.148
04	-0.606	-1.645	1.165	-2.912
05	0.954	-1.287	0.099	-3.786
06	-1.287	-4.985	1.311	-4.985
07	-4.528	-4.985	1.38	-4.985
08	1.38	-4.528	-4.985	-4.985
09	1.374	-4.528	-4.216	-3.786
10	-1.984	-0.275	1.129	-4.528
11	-2.714	-3.256	-3.256	1.35
12	-3.625	-1.901	1.337	-4.216
13	0.81	-0.763	0.106	-1.753
14	0.494	-0.543	0.236	-0.666
15	0.758	-0.643	-0.34	-0.464
16	-0.143	0.201	0.211	-0.391

Standard thresholds

P-value	Threshold
0.001	1.32476
0.0005	2.75691
0.0001	5.73041