SPI1.H12RSNP.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	SPI1.H12RSNP.0.P.B
Gene (human)	SPI1 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Spi1
Gene synonyms (mouse)	Sfpi-1, Sfpi1
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	14
Consensus	RRWGRGGAAGTGvn
GC content	49.74%
Information content (bits; total / per base)	16.757 / 1.197
Data sources	ChIP-Seq
Aligned words	999

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	94 (173)	0.97	0.993	0.94	0.982	0.97	0.995	5.353	7.231	552.553	980.658
Mouse	158 (286)	0.977	0.995	0.955	0.99	0.978	0.996	5.53	7.375	576.568	945.0

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 2 experiments	median	0.592	0.587	0.537	0.544	0.516	0.524
Non-Methyl HT-SELEX, 2 experiments	best	0.621	0.617	0.553	0.56	0.524	0.534

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	5.48	213.973	0.384	0.293

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Tryptophan cluster factors {3.5} (TFClass)
TF family	Ets-related {3.5.2} (TFClass)
TF subfamily	SPI-like {3.5.2.5} (TFClass)
TFClass ID	TFClass: 3.5.2.5.1
HGNC	HGNC:11241
MGI	MGI:98282
EntrezGene (human)	GeneID:6688 (SSTAR profile)
EntrezGene (mouse)	GeneID:20375 (SSTAR profile)
UniProt ID (human)	SPI1_HUMAN
UniProt ID (mouse)	SPI1_MOUSE
UniProt AC (human)	P17947 (TFClass)
UniProt AC (mouse)	P17433 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	94 human, 158 mouse
HT-SELEX	2
Methyl-HT-SELEX	0

PCM	SPI1.H12RSNP.0.P.B.pcm
PWM	SPI1.H12RSNP.0.P.B.pwm
PFM	SPI1.H12RSNP.0.P.B.pfm
Alignment	SPI1.H12RSNP.0.P.B.words.tsv
Threshold to P-value map	SPI1.H12RSNP.0.P.B.thr
Motif in other formats
JASPAR format	SPI1.H12RSNP.0.P.B_jaspar_format.txt
MEME format	SPI1.H12RSNP.0.P.B_meme_format.meme
Transfac format	SPI1.H12RSNP.0.P.B_transfac_format.txt
Homer format	SPI1.H12RSNP.0.P.B_homer_format_0.001.txt SPI1.H12RSNP.0.P.B_homer_format_0.0005.txt SPI1.H12RSNP.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	736.0	29.0	154.0	80.0
02	753.0	26.0	166.0	54.0
03	718.0	5.0	98.0	178.0
04	103.0	32.0	861.0	3.0
05	649.0	86.0	262.0	2.0
06	56.0	0.0	943.0	0.0
07	0.0	0.0	999.0	0.0
08	999.0	0.0	0.0	0.0
09	998.0	0.0	0.0	1.0
10	7.0	122.0	870.0	0.0
11	32.0	41.0	7.0	919.0
12	7.0	113.0	873.0	6.0
13	205.0	270.0	422.0	102.0
14	225.0	282.0	296.0	196.0

PFM

	A	C	G	T
01	0.737	0.029	0.154	0.08
02	0.754	0.026	0.166	0.054
03	0.719	0.005	0.098	0.178
04	0.103	0.032	0.862	0.003
05	0.65	0.086	0.262	0.002
06	0.056	0.0	0.944	0.0
07	0.0	0.0	1.0	0.0
08	1.0	0.0	0.0	0.0
09	0.999	0.0	0.0	0.001
10	0.007	0.122	0.871	0.0
11	0.032	0.041	0.007	0.92
12	0.007	0.113	0.874	0.006
13	0.205	0.27	0.422	0.102
14	0.225	0.282	0.296	0.196

PWM

	A	C	G	T
01	1.076	-2.102	-0.479	-1.124
02	1.099	-2.205	-0.405	-1.507
03	1.052	-3.621	-0.925	-0.336
04	-0.876	-2.009	1.233	-3.974
05	0.951	-1.053	0.048	-4.212
06	-1.472	-4.981	1.324	-4.981
07	-4.981	-4.981	1.381	-4.981
08	1.381	-4.981	-4.981	-4.981
09	1.38	-4.981	-4.981	-4.524
10	-3.361	-0.709	1.243	-4.981
11	-2.009	-1.773	-3.361	1.298
12	-3.361	-0.785	1.247	-3.483
13	-0.196	0.077	0.522	-0.886
14	-0.104	0.121	0.169	-0.24

Standard thresholds

P-value	Threshold
0.001	1.40801
0.0005	2.86176
0.0001	5.87061