MotifSPI1.H12CORE.1.S.B
Gene (human)SPI1
(GeneCards)
Gene synonyms (human)
Gene (mouse)Spi1
Gene synonyms (mouse)Sfpi-1, Sfpi1
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length12
ConsensusdddvGGAAGKdn
GC content52.45%
Information content (bits; total / per base)9.835 / 0.82
Data sourcesHT-SELEX
Aligned words2311

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 94 (173) 0.932 0.966 0.862 0.929 0.915 0.957 3.593 4.116 412.824 743.0
Mouse 158 (286) 0.93 0.958 0.864 0.938 0.92 0.956 3.617 4.182 425.456 715.469

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Non-Methyl HT-SELEX, 2 experiments median 0.614 0.602 0.548 0.553 0.512 0.527
best 0.648 0.635 0.569 0.573 0.524 0.539

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 2.723 83.672 0.311 0.214
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classTryptophan cluster factors {3.5} (TFClass)
TF familyEts-related {3.5.2} (TFClass)
TF subfamilySPI-like {3.5.2.5} (TFClass)
TFClass IDTFClass: 3.5.2.5.1
HGNCHGNC:11241
MGIMGI:98282
EntrezGene (human)GeneID:6688
(SSTAR profile)
EntrezGene (mouse)GeneID:20375
(SSTAR profile)
UniProt ID (human)SPI1_HUMAN
UniProt ID (mouse)SPI1_MOUSE
UniProt AC (human)P17947
(TFClass)
UniProt AC (mouse)P17433
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 94 human, 158 mouse
HT-SELEX 2
Methyl-HT-SELEX 0
PCM
ACGT
01907.5262.5635.5505.5
02761.0200.0633.0717.0
03348.0248.01277.0438.0
04453.0654.01111.093.0
0512.080.02216.03.0
061.00.02307.03.0
072300.00.011.00.0
082228.03.069.011.0
09153.0218.01862.078.0
10284.0271.0337.01419.0
11775.5292.5714.5528.5
12656.5485.5657.5511.5
PFM
ACGT
010.3930.1140.2750.219
020.3290.0870.2740.31
030.1510.1070.5530.19
040.1960.2830.4810.04
050.0050.0350.9590.001
060.00.00.9980.001
070.9950.00.0050.0
080.9640.0010.030.005
090.0660.0940.8060.034
100.1230.1170.1460.614
110.3360.1270.3090.229
120.2840.210.2850.221
PWM
ACGT
010.45-0.7850.095-0.133
020.275-1.0550.0910.215
03-0.505-0.8410.791-0.276
04-0.2420.1240.652-1.809
05-3.728-1.9571.342-4.766
06-5.285-5.7021.382-4.766
071.379-5.702-3.802-5.702
081.347-4.766-2.101-3.802
09-1.319-0.9691.168-1.981
10-0.707-0.753-0.5370.897
110.294-0.6770.212-0.089
120.127-0.1730.129-0.121
Standard thresholds
P-value Threshold
0.001 4.959365
0.0005 5.88601
0.0001 7.496895