SPI1.H12CORE.1.S.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	SPI1.H12CORE.1.S.B
Gene (human)	SPI1 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Spi1
Gene synonyms (mouse)	Sfpi-1, Sfpi1
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	12
Consensus	dddvGGAAGKdn
GC content	52.45%
Information content (bits; total / per base)	9.835 / 0.82
Data sources	HT-SELEX
Aligned words	2311

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	94 (173)	0.932	0.966	0.862	0.929	0.915	0.957	3.593	4.116	412.824	743.0
Mouse	158 (286)	0.93	0.958	0.864	0.938	0.92	0.956	3.617	4.182	425.456	715.469

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 2 experiments	median	0.614	0.602	0.548	0.553	0.512	0.527
Non-Methyl HT-SELEX, 2 experiments	best	0.648	0.635	0.569	0.573	0.524	0.539

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	2.723	83.672	0.311	0.214

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Tryptophan cluster factors {3.5} (TFClass)
TF family	Ets-related {3.5.2} (TFClass)
TF subfamily	SPI-like {3.5.2.5} (TFClass)
TFClass ID	TFClass: 3.5.2.5.1
HGNC	HGNC:11241
MGI	MGI:98282
EntrezGene (human)	GeneID:6688 (SSTAR profile)
EntrezGene (mouse)	GeneID:20375 (SSTAR profile)
UniProt ID (human)	SPI1_HUMAN
UniProt ID (mouse)	SPI1_MOUSE
UniProt AC (human)	P17947 (TFClass)
UniProt AC (mouse)	P17433 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	94 human, 158 mouse
HT-SELEX	2
Methyl-HT-SELEX	0

PCM	SPI1.H12CORE.1.S.B.pcm
PWM	SPI1.H12CORE.1.S.B.pwm
PFM	SPI1.H12CORE.1.S.B.pfm
Alignment	SPI1.H12CORE.1.S.B.words.tsv
Threshold to P-value map	SPI1.H12CORE.1.S.B.thr
Motif in other formats
JASPAR format	SPI1.H12CORE.1.S.B_jaspar_format.txt
MEME format	SPI1.H12CORE.1.S.B_meme_format.meme
Transfac format	SPI1.H12CORE.1.S.B_transfac_format.txt
Homer format	SPI1.H12CORE.1.S.B_homer_format_0.001.txt SPI1.H12CORE.1.S.B_homer_format_0.0005.txt SPI1.H12CORE.1.S.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	907.5	262.5	635.5	505.5
02	761.0	200.0	633.0	717.0
03	348.0	248.0	1277.0	438.0
04	453.0	654.0	1111.0	93.0
05	12.0	80.0	2216.0	3.0
06	1.0	0.0	2307.0	3.0
07	2300.0	0.0	11.0	0.0
08	2228.0	3.0	69.0	11.0
09	153.0	218.0	1862.0	78.0
10	284.0	271.0	337.0	1419.0
11	775.5	292.5	714.5	528.5
12	656.5	485.5	657.5	511.5

PFM

	A	C	G	T
01	0.393	0.114	0.275	0.219
02	0.329	0.087	0.274	0.31
03	0.151	0.107	0.553	0.19
04	0.196	0.283	0.481	0.04
05	0.005	0.035	0.959	0.001
06	0.0	0.0	0.998	0.001
07	0.995	0.0	0.005	0.0
08	0.964	0.001	0.03	0.005
09	0.066	0.094	0.806	0.034
10	0.123	0.117	0.146	0.614
11	0.336	0.127	0.309	0.229
12	0.284	0.21	0.285	0.221

PWM

	A	C	G	T
01	0.45	-0.785	0.095	-0.133
02	0.275	-1.055	0.091	0.215
03	-0.505	-0.841	0.791	-0.276
04	-0.242	0.124	0.652	-1.809
05	-3.728	-1.957	1.342	-4.766
06	-5.285	-5.702	1.382	-4.766
07	1.379	-5.702	-3.802	-5.702
08	1.347	-4.766	-2.101	-3.802
09	-1.319	-0.969	1.168	-1.981
10	-0.707	-0.753	-0.537	0.897
11	0.294	-0.677	0.212	-0.089
12	0.127	-0.173	0.129	-0.121

Standard thresholds

P-value	Threshold
0.001	4.959365
0.0005	5.88601
0.0001	7.496895