SPI1.H12CORE.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	SPI1.H12CORE.0.P.B
Gene (human)	SPI1 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Spi1
Gene synonyms (mouse)	Sfpi-1, Sfpi1
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	14
Consensus	vRRWGRGGAAGTGv
GC content	48.22%
Information content (bits; total / per base)	16.092 / 1.149
Data sources	ChIP-Seq
Aligned words	1001

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	94 (173)	0.971	0.993	0.946	0.982	0.973	0.995	5.632	7.593	556.569	996.602
Mouse	158 (286)	0.978	0.995	0.957	0.991	0.98	0.996	5.705	7.506	582.672	940.131

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 2 experiments	median	0.597	0.593	0.541	0.548	0.518	0.527
Non-Methyl HT-SELEX, 2 experiments	best	0.628	0.624	0.558	0.565	0.527	0.537

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	4.979	194.168	0.385	0.292

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Tryptophan cluster factors {3.5} (TFClass)
TF family	Ets-related {3.5.2} (TFClass)
TF subfamily	SPI-like {3.5.2.5} (TFClass)
TFClass ID	TFClass: 3.5.2.5.1
HGNC	HGNC:11241
MGI	MGI:98282
EntrezGene (human)	GeneID:6688 (SSTAR profile)
EntrezGene (mouse)	GeneID:20375 (SSTAR profile)
UniProt ID (human)	SPI1_HUMAN
UniProt ID (mouse)	SPI1_MOUSE
UniProt AC (human)	P17947 (TFClass)
UniProt AC (mouse)	P17433 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	94 human, 158 mouse
HT-SELEX	2
Methyl-HT-SELEX	0

PCM	SPI1.H12CORE.0.P.B.pcm
PWM	SPI1.H12CORE.0.P.B.pwm
PFM	SPI1.H12CORE.0.P.B.pfm
Alignment	SPI1.H12CORE.0.P.B.words.tsv
Threshold to P-value map	SPI1.H12CORE.0.P.B.thr
Motif in other formats
JASPAR format	SPI1.H12CORE.0.P.B_jaspar_format.txt
MEME format	SPI1.H12CORE.0.P.B_meme_format.meme
Transfac format	SPI1.H12CORE.0.P.B_transfac_format.txt
Homer format	SPI1.H12CORE.0.P.B_homer_format_0.001.txt SPI1.H12CORE.0.P.B_homer_format_0.0005.txt SPI1.H12CORE.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	430.0	133.0	338.0	100.0
02	689.0	48.0	159.0	105.0
03	648.0	49.0	225.0	79.0
04	673.0	7.0	111.0	210.0
05	96.0	66.0	826.0	13.0
06	722.0	66.0	208.0	5.0
07	41.0	0.0	960.0	0.0
08	0.0	1.0	1000.0	0.0
09	1000.0	1.0	0.0	0.0
10	1000.0	0.0	0.0	1.0
11	15.0	146.0	840.0	0.0
12	44.0	30.0	6.0	921.0
13	11.0	144.0	836.0	10.0
14	342.0	251.0	306.0	102.0

PFM

	A	C	G	T
01	0.43	0.133	0.338	0.1
02	0.688	0.048	0.159	0.105
03	0.647	0.049	0.225	0.079
04	0.672	0.007	0.111	0.21
05	0.096	0.066	0.825	0.013
06	0.721	0.066	0.208	0.005
07	0.041	0.0	0.959	0.0
08	0.0	0.001	0.999	0.0
09	0.999	0.001	0.0	0.0
10	0.999	0.0	0.0	0.001
11	0.015	0.146	0.839	0.0
12	0.044	0.03	0.006	0.92
13	0.011	0.144	0.835	0.01
14	0.342	0.251	0.306	0.102

PWM

	A	C	G	T
01	0.538	-0.626	0.299	-0.907
02	1.008	-1.623	-0.45	-0.859
03	0.947	-1.603	-0.106	-1.138
04	0.985	-3.363	-0.804	-0.174
05	-0.947	-1.314	1.189	-2.84
06	1.055	-1.314	-0.184	-3.623
07	-1.775	-4.983	1.339	-4.983
08	-4.983	-4.526	1.38	-4.983
09	1.38	-4.526	-4.983	-4.983
10	1.38	-4.983	-4.983	-4.526
11	-2.712	-0.534	1.206	-4.983
12	-1.707	-2.072	-3.485	1.298
13	-2.986	-0.548	1.201	-3.067
14	0.311	0.003	0.2	-0.888

Standard thresholds

P-value	Threshold
0.001	1.91901
0.0005	3.31486
0.0001	6.18871