MotifSPI1.H12CORE.0.P.B
Gene (human)SPI1
(GeneCards)
Gene synonyms (human)
Gene (mouse)Spi1
Gene synonyms (mouse)Sfpi-1, Sfpi1
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length14
ConsensusvRRWGRGGAAGTGv
GC content48.22%
Information content (bits; total / per base)16.092 / 1.149
Data sourcesChIP-Seq
Aligned words1001

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 94 (173) 0.971 0.993 0.946 0.982 0.973 0.995 5.632 7.593 556.569 996.602
Mouse 158 (286) 0.978 0.995 0.957 0.991 0.98 0.996 5.705 7.506 582.672 940.131

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Non-Methyl HT-SELEX, 2 experiments median 0.597 0.593 0.541 0.548 0.518 0.527
best 0.628 0.624 0.558 0.565 0.527 0.537

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 4.979 194.168 0.385 0.292
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classTryptophan cluster factors {3.5} (TFClass)
TF familyEts-related {3.5.2} (TFClass)
TF subfamilySPI-like {3.5.2.5} (TFClass)
TFClass IDTFClass: 3.5.2.5.1
HGNCHGNC:11241
MGIMGI:98282
EntrezGene (human)GeneID:6688
(SSTAR profile)
EntrezGene (mouse)GeneID:20375
(SSTAR profile)
UniProt ID (human)SPI1_HUMAN
UniProt ID (mouse)SPI1_MOUSE
UniProt AC (human)P17947
(TFClass)
UniProt AC (mouse)P17433
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 94 human, 158 mouse
HT-SELEX 2
Methyl-HT-SELEX 0
PCM
ACGT
01430.0133.0338.0100.0
02689.048.0159.0105.0
03648.049.0225.079.0
04673.07.0111.0210.0
0596.066.0826.013.0
06722.066.0208.05.0
0741.00.0960.00.0
080.01.01000.00.0
091000.01.00.00.0
101000.00.00.01.0
1115.0146.0840.00.0
1244.030.06.0921.0
1311.0144.0836.010.0
14342.0251.0306.0102.0
PFM
ACGT
010.430.1330.3380.1
020.6880.0480.1590.105
030.6470.0490.2250.079
040.6720.0070.1110.21
050.0960.0660.8250.013
060.7210.0660.2080.005
070.0410.00.9590.0
080.00.0010.9990.0
090.9990.0010.00.0
100.9990.00.00.001
110.0150.1460.8390.0
120.0440.030.0060.92
130.0110.1440.8350.01
140.3420.2510.3060.102
PWM
ACGT
010.538-0.6260.299-0.907
021.008-1.623-0.45-0.859
030.947-1.603-0.106-1.138
040.985-3.363-0.804-0.174
05-0.947-1.3141.189-2.84
061.055-1.314-0.184-3.623
07-1.775-4.9831.339-4.983
08-4.983-4.5261.38-4.983
091.38-4.526-4.983-4.983
101.38-4.983-4.983-4.526
11-2.712-0.5341.206-4.983
12-1.707-2.072-3.4851.298
13-2.986-0.5481.201-3.067
140.3110.0030.2-0.888
Standard thresholds
P-value Threshold
0.001 1.91901
0.0005 3.31486
0.0001 6.18871