SP9.H12INVIVO.1.S.C motif - HOmo sapiens COmprehensive MOdel COllection

Motif	SP9.H12INVIVO.1.S.C
Gene (human)	SP9 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Sp9
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	C

Motif length	16
Consensus	bddddRKGGGCGTGdn
GC content	69.15%
Information content (bits; total / per base)	15.346 / 0.959
Data sources	HT-SELEX
Aligned words	2025

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Mouse	2 (14)	0.518	0.543	0.369	0.399	0.552	0.577	1.463	1.638	0.0	0.658

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 1 experiments	median	0.936	0.891	0.894	0.85	0.774	0.758
Non-Methyl HT-SELEX, 1 experiments	best	0.936	0.891	0.894	0.85	0.774	0.758

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 2	0.513	0.023	0.07	-0.053

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	Three-zinc finger Kruppel-related {2.3.1} (TFClass)
TF subfamily	Sp1-like {2.3.1.1} (TFClass)
TFClass ID	TFClass: 2.3.1.1.9
HGNC	HGNC:30690
MGI	MGI:3574660
EntrezGene (human)	GeneID:100131390 (SSTAR profile)
EntrezGene (mouse)	GeneID:381373 (SSTAR profile)
UniProt ID (human)	SP9_HUMAN
UniProt ID (mouse)	SP9_MOUSE
UniProt AC (human)	P0CG40 (TFClass)
UniProt AC (mouse)	Q64HY3 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 2 mouse
HT-SELEX	1
Methyl-HT-SELEX	0

PCM	SP9.H12INVIVO.1.S.C.pcm
PWM	SP9.H12INVIVO.1.S.C.pwm
PFM	SP9.H12INVIVO.1.S.C.pfm
Alignment	SP9.H12INVIVO.1.S.C.words.tsv
Threshold to P-value map	SP9.H12INVIVO.1.S.C.thr
Motif in other formats
JASPAR format	SP9.H12INVIVO.1.S.C_jaspar_format.txt
MEME format	SP9.H12INVIVO.1.S.C_meme_format.meme
Transfac format	SP9.H12INVIVO.1.S.C_transfac_format.txt
Homer format	SP9.H12INVIVO.1.S.C_homer_format_0.001.txt SP9.H12INVIVO.1.S.C_homer_format_0.0005.txt SP9.H12INVIVO.1.S.C_homer_format_0.0001.txt

PCM

	A	C	G	T
01	309.5	312.5	999.5	403.5
02	304.25	258.25	1029.25	433.25
03	353.0	278.0	963.0	431.0
04	424.0	307.0	942.0	352.0
05	531.0	238.0	927.0	329.0
06	521.0	55.0	1296.0	153.0
07	331.0	14.0	797.0	883.0
08	71.0	0.0	1954.0	0.0
09	0.0	0.0	2025.0	0.0
10	0.0	0.0	2025.0	0.0
11	1.0	2024.0	0.0	0.0
12	0.0	0.0	2025.0	0.0
13	0.0	0.0	4.0	2021.0
14	241.0	15.0	1605.0	164.0
15	362.25	99.25	1148.25	415.25
16	326.5	428.5	636.5	633.5

PFM

	A	C	G	T
01	0.153	0.154	0.494	0.199
02	0.15	0.128	0.508	0.214
03	0.174	0.137	0.476	0.213
04	0.209	0.152	0.465	0.174
05	0.262	0.118	0.458	0.162
06	0.257	0.027	0.64	0.076
07	0.163	0.007	0.394	0.436
08	0.035	0.0	0.965	0.0
09	0.0	0.0	1.0	0.0
10	0.0	0.0	1.0	0.0
11	0.0	1.0	0.0	0.0
12	0.0	0.0	1.0	0.0
13	0.0	0.0	0.002	0.998
14	0.119	0.007	0.793	0.081
15	0.179	0.049	0.567	0.205
16	0.161	0.212	0.314	0.313

PWM

	A	C	G	T
01	-0.49	-0.48	0.678	-0.226
02	-0.507	-0.67	0.708	-0.155
03	-0.359	-0.596	0.641	-0.16
04	-0.177	-0.498	0.619	-0.362
05	0.048	-0.751	0.603	-0.429
06	0.029	-2.189	0.938	-1.188
07	-0.423	-3.464	0.452	0.555
08	-1.942	-5.587	1.348	-5.587
09	-5.587	-5.587	1.383	-5.587
10	-5.587	-5.587	1.383	-5.587
11	-5.165	1.383	-5.587	-5.587
12	-5.587	-5.587	1.383	-5.587
13	-5.587	-5.587	-4.455	1.382
14	-0.738	-3.403	1.151	-1.119
15	-0.333	-1.614	0.817	-0.197
16	-0.437	-0.166	0.228	0.223

Standard thresholds

P-value	Threshold
0.001	1.17426
0.0005	2.66256
0.0001	6.19636