SP8.H12INVIVO.0.SM.D motif - HOmo sapiens COmprehensive MOdel COllection

Motif	SP8.H12INVIVO.0.SM.D
Gene (human)	SP8 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Sp8
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	D

Motif length	12
Consensus	dRKGGGCGTRdn
GC content	68.47%
Information content (bits; total / per base)	14.574 / 1.214
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	6915

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.755	0.727	0.727	0.7	0.697	0.672
Overall, 4 experiments	best	0.953	0.923	0.941	0.905	0.907	0.869
Methyl HT-SELEX, 1 experiments	median	0.923	0.875	0.907	0.855	0.866	0.816
Methyl HT-SELEX, 1 experiments	best	0.923	0.875	0.907	0.855	0.866	0.816
Non-Methyl HT-SELEX, 3 experiments	median	0.587	0.579	0.548	0.545	0.527	0.528
Non-Methyl HT-SELEX, 3 experiments	best	0.953	0.923	0.941	0.905	0.907	0.869

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	Three-zinc finger Kruppel-related {2.3.1} (TFClass)
TF subfamily	Sp1-like {2.3.1.1} (TFClass)
TFClass ID	TFClass: 2.3.1.1.8
HGNC	HGNC:19196
MGI	MGI:2443471
EntrezGene (human)	GeneID:221833 (SSTAR profile)
EntrezGene (mouse)	GeneID:320145 (SSTAR profile)
UniProt ID (human)	SP8_HUMAN
UniProt ID (mouse)	SP8_MOUSE
UniProt AC (human)	Q8IXZ3 (TFClass)
UniProt AC (mouse)	Q8BMJ8 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	3
Methyl-HT-SELEX	1

PCM	SP8.H12INVIVO.0.SM.D.pcm
PWM	SP8.H12INVIVO.0.SM.D.pwm
PFM	SP8.H12INVIVO.0.SM.D.pfm
Alignment	SP8.H12INVIVO.0.SM.D.words.tsv
Threshold to P-value map	SP8.H12INVIVO.0.SM.D.thr
Motif in other formats
JASPAR format	SP8.H12INVIVO.0.SM.D_jaspar_format.txt
MEME format	SP8.H12INVIVO.0.SM.D_meme_format.meme
Transfac format	SP8.H12INVIVO.0.SM.D_transfac_format.txt
Homer format	SP8.H12INVIVO.0.SM.D_homer_format_0.001.txt SP8.H12INVIVO.0.SM.D_homer_format_0.0005.txt SP8.H12INVIVO.0.SM.D_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1911.5	768.5	2643.5	1591.5
02	1675.5	183.5	4319.5	736.5
03	824.0	0.0	1728.0	4363.0
04	126.0	0.0	6789.0	0.0
05	0.0	0.0	6915.0	0.0
06	0.0	0.0	6915.0	0.0
07	0.0	6915.0	0.0	0.0
08	0.0	0.0	6915.0	0.0
09	0.0	0.0	25.0	6890.0
10	1105.0	60.0	5319.0	431.0
11	1669.5	221.5	3131.5	1892.5
12	1471.75	2059.75	1906.75	1476.75

PFM

	A	C	G	T
01	0.276	0.111	0.382	0.23
02	0.242	0.027	0.625	0.107
03	0.119	0.0	0.25	0.631
04	0.018	0.0	0.982	0.0
05	0.0	0.0	1.0	0.0
06	0.0	0.0	1.0	0.0
07	0.0	1.0	0.0	0.0
08	0.0	0.0	1.0	0.0
09	0.0	0.0	0.004	0.996
10	0.16	0.009	0.769	0.062
11	0.241	0.032	0.453	0.274
12	0.213	0.298	0.276	0.214

PWM

	A	C	G	T
01	0.1	-0.809	0.424	-0.083
02	-0.031	-2.232	0.915	-0.852
03	-0.74	-6.663	-0.0	0.925
04	-2.603	-6.663	1.367	-6.663
05	-6.663	-6.663	1.385	-6.663
06	-6.663	-6.663	1.385	-6.663
07	-6.663	1.385	-6.663	-6.663
08	-6.663	-6.663	1.385	-6.663
09	-6.663	-6.663	-4.153	1.382
10	-0.447	-3.326	1.123	-1.385
11	-0.035	-2.046	0.594	0.09
12	-0.161	0.175	0.098	-0.157

Standard thresholds

P-value	Threshold
0.001	0.54402
0.0005	2.052015
0.0001	6.37928