| Motif | SP8.H12CORE.0.SM.B |
| Gene (human) | SP8 (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Sp8 |
| Gene synonyms (mouse) | |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | B |
| Motif | SP8.H12CORE.0.SM.B |
| Gene (human) | SP8 (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Sp8 |
| Gene synonyms (mouse) | |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | B |
| Motif length | 12 |
| Consensus | dRKGGGCGTRdn |
| GC content | 68.47% |
| Information content (bits; total / per base) | 14.574 / 1.214 |
| Data sources | HT-SELEX + Methyl-HT-SELEX |
| Aligned words | 6915 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 4 experiments | median | 0.755 | 0.727 | 0.727 | 0.7 | 0.697 | 0.672 |
| best | 0.953 | 0.923 | 0.941 | 0.905 | 0.907 | 0.869 | |
| Methyl HT-SELEX, 1 experiments | median | 0.923 | 0.875 | 0.907 | 0.855 | 0.866 | 0.816 |
| best | 0.923 | 0.875 | 0.907 | 0.855 | 0.866 | 0.816 | |
| Non-Methyl HT-SELEX, 3 experiments | median | 0.587 | 0.579 | 0.548 | 0.545 | 0.527 | 0.528 |
| best | 0.953 | 0.923 | 0.941 | 0.905 | 0.907 | 0.869 | |
| TF superclass | Zinc-coordinating DNA-binding domains {2} (TFClass) |
| TF class | C2H2 zinc finger factors {2.3} (TFClass) |
| TF family | Three-zinc finger Kruppel-related {2.3.1} (TFClass) |
| TF subfamily | Sp1-like {2.3.1.1} (TFClass) |
| TFClass ID | TFClass: 2.3.1.1.8 |
| HGNC | HGNC:19196 |
| MGI | MGI:2443471 |
| EntrezGene (human) | GeneID:221833 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:320145 (SSTAR profile) |
| UniProt ID (human) | SP8_HUMAN |
| UniProt ID (mouse) | SP8_MOUSE |
| UniProt AC (human) | Q8IXZ3 (TFClass) |
| UniProt AC (mouse) | Q8BMJ8 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 0 human, 0 mouse |
| HT-SELEX | 3 |
| Methyl-HT-SELEX | 1 |
| PCM | SP8.H12CORE.0.SM.B.pcm |
| PWM | SP8.H12CORE.0.SM.B.pwm |
| PFM | SP8.H12CORE.0.SM.B.pfm |
| Alignment | SP8.H12CORE.0.SM.B.words.tsv |
| Threshold to P-value map | SP8.H12CORE.0.SM.B.thr |
| Motif in other formats | |
| JASPAR format | SP8.H12CORE.0.SM.B_jaspar_format.txt |
| MEME format | SP8.H12CORE.0.SM.B_meme_format.meme |
| Transfac format | SP8.H12CORE.0.SM.B_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 1911.5 | 768.5 | 2643.5 | 1591.5 |
| 02 | 1675.5 | 183.5 | 4319.5 | 736.5 |
| 03 | 824.0 | 0.0 | 1728.0 | 4363.0 |
| 04 | 126.0 | 0.0 | 6789.0 | 0.0 |
| 05 | 0.0 | 0.0 | 6915.0 | 0.0 |
| 06 | 0.0 | 0.0 | 6915.0 | 0.0 |
| 07 | 0.0 | 6915.0 | 0.0 | 0.0 |
| 08 | 0.0 | 0.0 | 6915.0 | 0.0 |
| 09 | 0.0 | 0.0 | 25.0 | 6890.0 |
| 10 | 1105.0 | 60.0 | 5319.0 | 431.0 |
| 11 | 1669.5 | 221.5 | 3131.5 | 1892.5 |
| 12 | 1471.75 | 2059.75 | 1906.75 | 1476.75 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.276 | 0.111 | 0.382 | 0.23 |
| 02 | 0.242 | 0.027 | 0.625 | 0.107 |
| 03 | 0.119 | 0.0 | 0.25 | 0.631 |
| 04 | 0.018 | 0.0 | 0.982 | 0.0 |
| 05 | 0.0 | 0.0 | 1.0 | 0.0 |
| 06 | 0.0 | 0.0 | 1.0 | 0.0 |
| 07 | 0.0 | 1.0 | 0.0 | 0.0 |
| 08 | 0.0 | 0.0 | 1.0 | 0.0 |
| 09 | 0.0 | 0.0 | 0.004 | 0.996 |
| 10 | 0.16 | 0.009 | 0.769 | 0.062 |
| 11 | 0.241 | 0.032 | 0.453 | 0.274 |
| 12 | 0.213 | 0.298 | 0.276 | 0.214 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.1 | -0.809 | 0.424 | -0.083 |
| 02 | -0.031 | -2.232 | 0.915 | -0.852 |
| 03 | -0.74 | -6.663 | -0.0 | 0.925 |
| 04 | -2.603 | -6.663 | 1.367 | -6.663 |
| 05 | -6.663 | -6.663 | 1.385 | -6.663 |
| 06 | -6.663 | -6.663 | 1.385 | -6.663 |
| 07 | -6.663 | 1.385 | -6.663 | -6.663 |
| 08 | -6.663 | -6.663 | 1.385 | -6.663 |
| 09 | -6.663 | -6.663 | -4.153 | 1.382 |
| 10 | -0.447 | -3.326 | 1.123 | -1.385 |
| 11 | -0.035 | -2.046 | 0.594 | 0.09 |
| 12 | -0.161 | 0.175 | 0.098 | -0.157 |
| P-value | Threshold |
|---|---|
| 0.001 | 0.54402 |
| 0.0005 | 2.052015 |
| 0.0001 | 6.37928 |