MotifSP8.H12CORE.0.SM.B
Gene (human)SP8
(GeneCards)
Gene synonyms (human)
Gene (mouse)Sp8
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length12
ConsensusdRKGGGCGTRdn
GC content68.47%
Information content (bits; total / per base)14.574 / 1.214
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words6915

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.755 0.727 0.727 0.7 0.697 0.672
best 0.953 0.923 0.941 0.905 0.907 0.869
Methyl HT-SELEX, 1 experiments median 0.923 0.875 0.907 0.855 0.866 0.816
best 0.923 0.875 0.907 0.855 0.866 0.816
Non-Methyl HT-SELEX, 3 experiments median 0.587 0.579 0.548 0.545 0.527 0.528
best 0.953 0.923 0.941 0.905 0.907 0.869
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classC2H2 zinc finger factors {2.3} (TFClass)
TF familyThree-zinc finger Kruppel-related {2.3.1} (TFClass)
TF subfamilySp1-like {2.3.1.1} (TFClass)
TFClass IDTFClass: 2.3.1.1.8
HGNCHGNC:19196
MGIMGI:2443471
EntrezGene (human)GeneID:221833
(SSTAR profile)
EntrezGene (mouse)GeneID:320145
(SSTAR profile)
UniProt ID (human)SP8_HUMAN
UniProt ID (mouse)SP8_MOUSE
UniProt AC (human)Q8IXZ3
(TFClass)
UniProt AC (mouse)Q8BMJ8
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
011911.5768.52643.51591.5
021675.5183.54319.5736.5
03824.00.01728.04363.0
04126.00.06789.00.0
050.00.06915.00.0
060.00.06915.00.0
070.06915.00.00.0
080.00.06915.00.0
090.00.025.06890.0
101105.060.05319.0431.0
111669.5221.53131.51892.5
121471.752059.751906.751476.75
PFM
ACGT
010.2760.1110.3820.23
020.2420.0270.6250.107
030.1190.00.250.631
040.0180.00.9820.0
050.00.01.00.0
060.00.01.00.0
070.01.00.00.0
080.00.01.00.0
090.00.00.0040.996
100.160.0090.7690.062
110.2410.0320.4530.274
120.2130.2980.2760.214
PWM
ACGT
010.1-0.8090.424-0.083
02-0.031-2.2320.915-0.852
03-0.74-6.663-0.00.925
04-2.603-6.6631.367-6.663
05-6.663-6.6631.385-6.663
06-6.663-6.6631.385-6.663
07-6.6631.385-6.663-6.663
08-6.663-6.6631.385-6.663
09-6.663-6.663-4.1531.382
10-0.447-3.3261.123-1.385
11-0.035-2.0460.5940.09
12-0.1610.1750.098-0.157
Standard thresholds
P-value Threshold
0.001 0.54402
0.0005 2.052015
0.0001 6.37928