SP5.H12CORE.1.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	SP5.H12CORE.1.P.B
Gene (human)	SP5 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Sp5
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	25
Consensus	vddRRvddRRvdRRGGGMGGRGvdv
GC content	66.2%
Information content (bits; total / per base)	16.003 / 0.64
Data sources	ChIP-Seq
Aligned words	994

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	4 (25)	0.736	0.871	0.554	0.73	0.81	0.941	3.196	5.228	22.337	76.886
Mouse	1 (6)	0.841	0.845	0.694	0.704	0.869	0.877	4.273	4.46	93.166	102.959

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	Three-zinc finger Kruppel-related {2.3.1} (TFClass)
TF subfamily	Sp1-like {2.3.1.1} (TFClass)
TFClass ID	TFClass: 2.3.1.1.5
HGNC	HGNC:14529
MGI	MGI:1927715
EntrezGene (human)	GeneID:389058 (SSTAR profile)
EntrezGene (mouse)	GeneID:64406 (SSTAR profile)
UniProt ID (human)	SP5_HUMAN
UniProt ID (mouse)	SP5_MOUSE
UniProt AC (human)	Q6BEB4 (TFClass)
UniProt AC (mouse)	Q9JHX2 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	4 human, 1 mouse
HT-SELEX	0
Methyl-HT-SELEX	0

PCM	SP5.H12CORE.1.P.B.pcm
PWM	SP5.H12CORE.1.P.B.pwm
PFM	SP5.H12CORE.1.P.B.pfm
Alignment	SP5.H12CORE.1.P.B.words.tsv
Threshold to P-value map	SP5.H12CORE.1.P.B.thr
Motif in other formats
JASPAR format	SP5.H12CORE.1.P.B_jaspar_format.txt
MEME format	SP5.H12CORE.1.P.B_meme_format.meme
Transfac format	SP5.H12CORE.1.P.B_transfac_format.txt
Homer format	SP5.H12CORE.1.P.B_homer_format_0.001.txt SP5.H12CORE.1.P.B_homer_format_0.0005.txt SP5.H12CORE.1.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	227.0	155.0	478.0	134.0
02	249.0	96.0	457.0	192.0
03	322.0	78.0	507.0	87.0
04	224.0	74.0	607.0	89.0
05	203.0	73.0	636.0	82.0
06	347.0	129.0	409.0	109.0
07	187.0	105.0	579.0	123.0
08	221.0	103.0	558.0	112.0
09	272.0	58.0	558.0	106.0
10	144.0	75.0	682.0	93.0
11	278.0	155.0	457.0	104.0
12	441.0	105.0	270.0	178.0
13	236.0	91.0	576.0	91.0
14	234.0	27.0	532.0	201.0
15	245.0	4.0	731.0	14.0
16	28.0	2.0	958.0	6.0
17	19.0	26.0	930.0	19.0
18	587.0	275.0	4.0	128.0
19	58.0	1.0	912.0	23.0
20	16.0	7.0	911.0	60.0
21	473.0	3.0	501.0	17.0
22	51.0	24.0	891.0	28.0
23	247.0	533.0	120.0	94.0
24	428.0	146.0	179.0	241.0
25	216.0	138.0	525.0	115.0

PFM

	A	C	G	T
01	0.228	0.156	0.481	0.135
02	0.251	0.097	0.46	0.193
03	0.324	0.078	0.51	0.088
04	0.225	0.074	0.611	0.09
05	0.204	0.073	0.64	0.082
06	0.349	0.13	0.411	0.11
07	0.188	0.106	0.582	0.124
08	0.222	0.104	0.561	0.113
09	0.274	0.058	0.561	0.107
10	0.145	0.075	0.686	0.094
11	0.28	0.156	0.46	0.105
12	0.444	0.106	0.272	0.179
13	0.237	0.092	0.579	0.092
14	0.235	0.027	0.535	0.202
15	0.246	0.004	0.735	0.014
16	0.028	0.002	0.964	0.006
17	0.019	0.026	0.936	0.019
18	0.591	0.277	0.004	0.129
19	0.058	0.001	0.918	0.023
20	0.016	0.007	0.916	0.06
21	0.476	0.003	0.504	0.017
22	0.051	0.024	0.896	0.028
23	0.248	0.536	0.121	0.095
24	0.431	0.147	0.18	0.242
25	0.217	0.139	0.528	0.116

PWM

	A	C	G	T
01	-0.09	-0.468	0.651	-0.612
02	0.002	-0.94	0.606	-0.256
03	0.258	-1.144	0.71	-1.037
04	-0.103	-1.195	0.889	-1.015
05	-0.201	-1.209	0.936	-1.095
06	0.332	-0.649	0.496	-0.815
07	-0.282	-0.852	0.842	-0.696
08	-0.116	-0.871	0.805	-0.789
09	0.09	-1.433	0.805	-0.843
10	-0.541	-1.182	1.005	-0.971
11	0.111	-0.468	0.606	-0.862
12	0.571	-0.852	0.082	-0.331
13	-0.051	-0.993	0.837	-0.993
14	-0.06	-2.165	0.758	-0.211
15	-0.014	-3.777	1.074	-2.767
16	-2.13	-4.207	1.344	-3.478
17	-2.491	-2.2	1.315	-2.491
18	0.856	0.101	-3.777	-0.657
19	-1.433	-4.52	1.295	-2.315
20	-2.647	-3.356	1.294	-1.4
21	0.64	-3.969	0.698	-2.592
22	-1.557	-2.275	1.272	-2.13
23	-0.006	0.759	-0.721	-0.961
24	0.541	-0.527	-0.325	-0.03
25	-0.139	-0.583	0.744	-0.763

Standard thresholds

P-value	Threshold
0.001	2.89286
0.0005	4.02146
0.0001	6.39271