SP5.H12CORE.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	SP5.H12CORE.0.P.B
Gene (human)	SP5 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Sp5
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	14
Consensus	nvKGGGMGGRGMnv
GC content	74.49%
Information content (bits; total / per base)	12.98 / 0.927
Data sources	ChIP-Seq
Aligned words	997

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	4 (25)	0.821	0.882	0.617	0.722	0.839	0.937	2.933	3.694	34.201	203.796
Mouse	1 (6)	0.882	0.887	0.769	0.779	0.867	0.872	3.208	3.281	148.105	158.444

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	Three-zinc finger Kruppel-related {2.3.1} (TFClass)
TF subfamily	Sp1-like {2.3.1.1} (TFClass)
TFClass ID	TFClass: 2.3.1.1.5
HGNC	HGNC:14529
MGI	MGI:1927715
EntrezGene (human)	GeneID:389058 (SSTAR profile)
EntrezGene (mouse)	GeneID:64406 (SSTAR profile)
UniProt ID (human)	SP5_HUMAN
UniProt ID (mouse)	SP5_MOUSE
UniProt AC (human)	Q6BEB4 (TFClass)
UniProt AC (mouse)	Q9JHX2 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	4 human, 1 mouse
HT-SELEX	0
Methyl-HT-SELEX	0

PCM	SP5.H12CORE.0.P.B.pcm
PWM	SP5.H12CORE.0.P.B.pwm
PFM	SP5.H12CORE.0.P.B.pfm
Alignment	SP5.H12CORE.0.P.B.words.tsv
Threshold to P-value map	SP5.H12CORE.0.P.B.thr
Motif in other formats
JASPAR format	SP5.H12CORE.0.P.B_jaspar_format.txt
MEME format	SP5.H12CORE.0.P.B_meme_format.meme
Transfac format	SP5.H12CORE.0.P.B_transfac_format.txt
Homer format	SP5.H12CORE.0.P.B_homer_format_0.001.txt SP5.H12CORE.0.P.B_homer_format_0.0005.txt SP5.H12CORE.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	366.0	161.0	287.0	183.0
02	212.0	133.0	579.0	73.0
03	148.0	27.0	526.0	296.0
04	154.0	2.0	839.0	2.0
05	3.0	1.0	987.0	6.0
06	2.0	9.0	982.0	4.0
07	278.0	593.0	2.0	124.0
08	21.0	3.0	965.0	8.0
09	1.0	1.0	948.0	47.0
10	356.0	13.0	599.0	29.0
11	81.0	38.0	834.0	44.0
12	244.0	616.0	55.0	82.0
13	363.0	226.0	213.0	195.0
14	144.0	208.0	550.0	95.0

PFM

	A	C	G	T
01	0.367	0.161	0.288	0.184
02	0.213	0.133	0.581	0.073
03	0.148	0.027	0.528	0.297
04	0.154	0.002	0.842	0.002
05	0.003	0.001	0.99	0.006
06	0.002	0.009	0.985	0.004
07	0.279	0.595	0.002	0.124
08	0.021	0.003	0.968	0.008
09	0.001	0.001	0.951	0.047
10	0.357	0.013	0.601	0.029
11	0.081	0.038	0.837	0.044
12	0.245	0.618	0.055	0.082
13	0.364	0.227	0.214	0.196
14	0.144	0.209	0.552	0.095

PWM

	A	C	G	T
01	0.382	-0.433	0.14	-0.306
02	-0.161	-0.622	0.839	-1.212
03	-0.517	-2.168	0.743	0.171
04	-0.477	-4.21	1.209	-4.21
05	-3.972	-4.522	1.371	-3.481
06	-4.21	-3.153	1.366	-3.78
07	0.108	0.863	-4.21	-0.691
08	-2.402	-3.972	1.349	-3.251
09	-4.522	-4.522	1.331	-1.639
10	0.354	-2.836	0.873	-2.1
11	-1.11	-1.843	1.203	-1.703
12	-0.021	0.901	-1.487	-1.098
13	0.374	-0.097	-0.156	-0.244
14	-0.544	-0.18	0.788	-0.953

Standard thresholds

P-value	Threshold
0.001	3.67256
0.0005	4.80661
0.0001	7.12611