SP4.H12INVIVO.0.P.C motif - HOmo sapiens COmprehensive MOdel COllection

Motif	SP4.H12INVIVO.0.P.C
Gene (human)	SP4 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Sp4
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	C

Motif length	15
Consensus	vvKRGGCGKRRYbdv
GC content	71.77%
Information content (bits; total / per base)	9.653 / 0.644
Data sources	ChIP-Seq
Aligned words	868

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	2 (12)	0.755	0.855	0.607	0.69	0.797	0.888	3.178	3.521	27.101	59.187

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 2 experiments	median	0.547	0.546	0.52	0.523	0.511	0.514
Non-Methyl HT-SELEX, 2 experiments	best	0.551	0.552	0.522	0.526	0.512	0.515

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	Three-zinc finger Kruppel-related {2.3.1} (TFClass)
TF subfamily	Sp1-like {2.3.1.1} (TFClass)
TFClass ID	TFClass: 2.3.1.1.4
HGNC	HGNC:11209
MGI	MGI:107595
EntrezGene (human)	GeneID:6671 (SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)	SP4_HUMAN
UniProt ID (mouse)	SP4_MOUSE
UniProt AC (human)	Q02446 (TFClass)
UniProt AC (mouse)	Q62445 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	2 human, 0 mouse
HT-SELEX	2
Methyl-HT-SELEX	0

PCM	SP4.H12INVIVO.0.P.C.pcm
PWM	SP4.H12INVIVO.0.P.C.pwm
PFM	SP4.H12INVIVO.0.P.C.pfm
Alignment	SP4.H12INVIVO.0.P.C.words.tsv
Threshold to P-value map	SP4.H12INVIVO.0.P.C.thr
Motif in other formats
JASPAR format	SP4.H12INVIVO.0.P.C_jaspar_format.txt
MEME format	SP4.H12INVIVO.0.P.C_meme_format.meme
Transfac format	SP4.H12INVIVO.0.P.C_transfac_format.txt
Homer format	SP4.H12INVIVO.0.P.C_homer_format_0.001.txt SP4.H12INVIVO.0.P.C_homer_format_0.0005.txt SP4.H12INVIVO.0.P.C_homer_format_0.0001.txt

PCM

	A	C	G	T
01	347.0	167.0	252.0	102.0
02	267.0	116.0	431.0	54.0
03	142.0	42.0	526.0	158.0
04	162.0	50.0	569.0	87.0
05	33.0	60.0	758.0	17.0
06	108.0	28.0	723.0	9.0
07	103.0	703.0	9.0	53.0
08	47.0	5.0	781.0	35.0
09	33.0	23.0	659.0	153.0
10	241.0	41.0	516.0	70.0
11	154.0	54.0	587.0	73.0
12	96.0	531.0	101.0	140.0
13	86.0	494.0	123.0	165.0
14	195.0	100.0	284.0	289.0
15	135.0	183.0	429.0	121.0

PFM

	A	C	G	T
01	0.4	0.192	0.29	0.118
02	0.308	0.134	0.497	0.062
03	0.164	0.048	0.606	0.182
04	0.187	0.058	0.656	0.1
05	0.038	0.069	0.873	0.02
06	0.124	0.032	0.833	0.01
07	0.119	0.81	0.01	0.061
08	0.054	0.006	0.9	0.04
09	0.038	0.026	0.759	0.176
10	0.278	0.047	0.594	0.081
11	0.177	0.062	0.676	0.084
12	0.111	0.612	0.116	0.161
13	0.099	0.569	0.142	0.19
14	0.225	0.115	0.327	0.333
15	0.156	0.211	0.494	0.139

PWM

	A	C	G	T
01	0.467	-0.26	0.148	-0.746
02	0.206	-0.62	0.682	-1.368
03	-0.42	-1.611	0.881	-0.314
04	-0.29	-1.442	0.959	-0.902
05	-1.841	-1.266	1.245	-2.46
06	-0.69	-1.997	1.198	-3.018
07	-0.737	1.17	-3.018	-1.386
08	-1.502	-3.487	1.275	-1.785
09	-1.841	-2.181	1.106	-0.346
10	0.104	-1.634	0.862	-1.115
11	-0.34	-1.368	0.99	-1.074
12	-0.806	0.89	-0.756	-0.434
13	-0.914	0.818	-0.562	-0.272
14	-0.106	-0.766	0.267	0.285
15	-0.47	-0.169	0.678	-0.578

Standard thresholds

P-value	Threshold
0.001	4.74201
0.0005	5.51466
0.0001	7.12646